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Medicine

D-Index
144
Citations
81142
World Ranking
1439
National Ranking
840

Research.com Recognitions

  • 2011 - Distinguished Fellowship Award, American College of Cardiology (ACC)

Overview

Charles Antzelevitch is affiliated with the Lankenau Institute for Medical Research in the United States. Their research primarily focuses on cardiac electrophysiology and arrhythmias, with extensive work in ion channel regulation and function. The main fields of study encompass Medicine and Biochemistry, Genetics, and Molecular Biology, with a particular emphasis on cardiology and cardiovascular medicine as well as molecular biology.

Antzelevitch has contributed significantly to topics such as:

  • Cardiac electrophysiology and arrhythmias
  • Ion channel regulation and function
  • Cardiac arrhythmias and treatments
  • Atrial fibrillation management and outcomes
  • ECG monitoring and analysis
  • RNA and protein synthesis mechanisms
  • Cardiomyopathy and myosin studies

The frequent publication venues for Antzelevitch include:

  • Heart Rhythm
  • Circulation
  • EBioMedicine
  • Nature Genetics
  • PLoS ONE

Some of the recent papers authored or co-authored by Antzelevitch are:

  • Inherited cardiac arrhythmias, 2020, Nature Reviews Disease Primers
  • Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome, 2020, Circulation
  • Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility, 2022, Nature Genetics
  • Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls, 2020, Genetics in Medicine
  • 2020, Institutional Repository University of Antwerp (University of Antwerp)

Frequent co-authors collaborating with Antzelevitch include:

  • Héctor Barajas-Martínez
  • Dan Hu
  • Alexander Burashnikov
  • Zhonghe Zhang
  • José M. Di Diego

Their research has been recognized with the Distinguished Fellowship Award from the American College of Cardiology in 2011.

Best Publications

  • Contemporary Definitions and Classification of the Cardiomyopathies An American Heart Association Scientific Statement From the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention

    Barry J. Maron;Jeffrey A. Towbin;Gaetano Thiene;Charles Antzelevitch

  • Brugada Syndrome: Report of the Second Consensus Conference Endorsed by the Heart Rhythm Society and the European Heart Rhythm Association

    Charles Antzelevitch;Pedro Brugada;Martin Borggrefe;Josep Brugada

  • Genetic basis and molecular mechanism for idiopathic ventricular fibrillation

    Qiuyun Chen;Glenn E. Kirsch;Danmei Zhang;Ramon Brugada

  • Proposed diagnostic criteria for the Brugada syndrome: consensus report.

    Arthur A.M. Wilde;Charles Antzelevitch;Martin Borggrefe;Josep Brugada

  • Cellular Basis for the Brugada Syndrome and Other Mechanisms of Arrhythmogenesis Associated With ST-Segment Elevation

    Gan-Xin Yan;Charles Antzelevitch

  • Cellular Basis for the Normal T Wave and the Electrocardiographic Manifestations of the Long-QT Syndrome

    Gan-Xin Yan;Charles Antzelevitch

  • Loss-of-Function Mutations in the Cardiac Calcium Channel Underlie a New Clinical Entity Characterized by ST-Segment Elevation, Short QT Intervals, and Sudden Cardiac Death

    Charles Antzelevitch;Guido D. Pollevick;Jonathan M. Cordeiro;Oscar Casis

  • Cellular Basis for the Electrocardiographic J Wave

    Gan-Xin Yan;Charles Antzelevitch

  • Sudden death associated with short-QT syndrome linked to mutations in HERG.

    Ramon Brugada;Kui Hong;Robert Dumaine;Jonathan Cordeiro

  • Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells.

    C. Antzelevitch;S. Sicouri;S. H. Litovsky;A. Lukas

  • Sodium Channel Blockers Identify Risk for Sudden Death in Patients With ST-Segment Elevation and Right Bundle Branch Block but Structurally Normal Hearts

    Ramon Brugada;Josep Brugada;Charles Antzelevitch;Glenn E. Kirsch

  • Long-Term Follow-Up of Individuals With the Electrocardiographic Pattern of Right Bundle-Branch Block and ST-Segment Elevation in Precordial Leads V1 to V3

    Josep Brugada;Ramon Brugada;Charles Antzelevitch;Jeffrey Towbin

  • Characteristics of the Delayed Rectifier Current (IKr and IKs) in Canine Ventricular Epicardial, Midmyocardial, and Endocardial Myocytes A Weaker IKs Contributes to the Longer Action Potential of the M Cell

    Da-Wei Liu;Charles Antzelevitch

  • Brugada syndrome: report of the second consensus conference

    Charles Antzelevitch;Pedro Brugada;Martin Borggrefe;Josep Brugada

  • An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing.

    Jamie D. Kapplinger;David J. Tester;Marielle Alders;Begoña Benito

  • Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties.

    Charles Antzelevitch;Luiz Belardinelli;Andrew C. Zygmunt;Alexander Burashnikov

  • Sodium Channel Block With Mexiletine Is Effective in Reducing Dispersion of Repolarization and Preventing Torsade de Pointes in LQT2 and LQT3 Models of the Long-QT Syndrome

    Wataru Shimizu;Charles Antzelevitch

  • J Wave Syndromes

    Charles Antzelevitch;Gan-Xin Yan;Gan-Xin Yan

  • J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge.

    Charles Antzelevitch;Gan Xin Yan;Michael J. Ackerman;Martin Borggrefe

  • The M cell: its contribution to the ECG and to normal and abnormal electrical function of the heart.

    C Antzelevitch;W Shimizu;G X Yan;S Sicouri

Frequent Co-Authors

Luiz Belardinelli
Luiz Belardinelli University of Florida
Josep Brugada
Josep Brugada University of Barcelona
Wataru Shimizu
Wataru Shimizu Nippon Medical School
Pedro Brugada
Pedro Brugada Vrije Universiteit Brussel
Arthur A.M. Wilde
Arthur A.M. Wilde University of Amsterdam
Ramon Brugada
Ramon Brugada University of Girona
Peter J. Schwartz
Peter J. Schwartz Istituto Auxologico Italiano
Domenico Corrado
Domenico Corrado University of Padua
José Jalife
José Jalife University of Michigan–Ann Arbor

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