Huck-Hui Ng

Research.com Recognitions

• 2024 - Research.com Genetics and Molecular Biology in Singapore Leader Award
• 2022 - Research.com Genetics and Molecular Biology in Singapore Leader Award

Overview

Best Publications

• Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

  Xinsheng Nan;Huck-Hui Ng;Colin A. Johnson;Carol D. Laherty

  4240
  Citations

• Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

  Xi Chen;Han Xu;Ping Yuan;Fang Fang;Fang Fang

  3049
  Citations

• The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells.

  Yuin Han Loh;Qiang Wu;Joon Lin Chew;Joon Lin Chew;Vinsensius B. Vega

  2998
  Citations

• Transcriptional regulation of nanog by OCT4 and SOX2.

  David J. Rodda;Joon-Lin Chew;Joon-Lin Chew;Leng-Hiong Lim;Yuin-Han Loh;Yuin-Han Loh

  1470
  Citations

• Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

  Yi Zhang;Huck-Hui Ng;Hediye Erdjument-Bromage;Paul Tempst

  1467
  Citations

• A global map of p53 transcription-factor binding sites in the human genome.

  Chia-Lin Wei;Qiang Wu;Vinsensius B. Vega;Kuo Ping Chiu

  1459
  Citations

• Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs.

  Simon Cawley;Stefan Bekiranov;Huck H Ng;Huck H Ng;Huck H Ng;Philipp Kapranov

  1448
  Citations

• Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity

  Huck Hui Ng;François Robert;Richard A. Young;Kevin Struhl

  1402
  Citations

• Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

  Linda S.-H. Chuang;Hang-In Ian;Tong-Wey Koh;Huck-Hui Ng

  1192
  Citations

• MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex.

  Huck-Hui Ng;Yi Zhang;Brian Hendrich;Colin A Johnson

  1169
  Citations

• Methylation of H3-Lysine 79 Is Mediated by a New Family of HMTases without a SET Domain

  Qin Feng;Hengbin Wang;Huck Hui Ng;Hediye Erdjument-Bromage

  1014
  Citations

• Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells.

  Joon-Lin Chew;Yuin-Han Loh;Yuin-Han Loh;Wensheng Zhang;Xi Chen;Xi Chen

  896
  Citations

• A core Klf circuitry regulates self-renewal of embryonic stem cells

  Jianming Jiang;Yun-Shen Chan;Yun-Shen Chan;Yuin-Han Loh;Yuin-Han Loh;Jun Cai

  880
  Citations

• Transposable elements have rewired the core regulatory network of human embryonic stem cells

  Galih Kunarso;Na-Yu Chia;Na-Yu Chia;Justin Jeyakani;Catalina Hwang;Catalina Hwang

  862
  Citations

• Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons

  Junghyun Jo;Yixin Xiao;Alfred Xuyang Sun;Engin Cukuroglu

  848
  Citations

• DNA methylation and chromatin modification.

  Ng Hh;Bird A

  837
  Citations

• The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

  Brian Hendrich;Ulrike Hardeland;Huck-Hui Ng;Josef Jiricny

  766
  Citations

• Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells.

  Xiao Dong Zhao;Xu Han;Joon Lin Chew;Joon Lin Chew;Jun Liu

  687
  Citations

• Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

  Huck Hui Ng;Qin Feng;Hengbin Wang;Hediye Erdjument-Bromage

  663
  Citations

• Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1.

  Jinqiu Zhang;Wai-Leong Tam;Wai-Leong Tam;Guo Qing Tong;Qiang Wu

  655
  Citations