D-Index & Metrics Best Publications
Genetics and Molecular Biology
Singapore
2022

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 74 Citations 40,346 139 World Ranking 738 National Ranking 4

Research.com Recognitions

Awards & Achievements

2022 - Research.com Genetics and Molecular Biology in Singapore Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Gene expression

Huck-Hui Ng mainly investigates Cell biology, SOX2, Chromatin immunoprecipitation, Genetics and Transcription factor. His research in Cell biology focuses on subjects like Embryonic stem cell, which are connected to Molecular biology. His SOX2 research is multidisciplinary, relying on both Reprogramming and Homeobox protein NANOG.

As a part of the same scientific family, he mostly works in the field of Chromatin immunoprecipitation, focusing on Nanog Homeobox Protein and, on occasion, Octamer Transcription Factor-3. As part of his studies on Transcription factor, he often connects relevant subjects like Rex1. The various areas that Huck-Hui Ng examines in his Stem cell study include Induced stem cells and Embryoid body.

His most cited work include:

  • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex (2870 citations)
  • Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells (2126 citations)
  • Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells (2126 citations)

What are the main themes of his work throughout his whole career to date?

Cell biology, Embryonic stem cell, Induced pluripotent stem cell, Genetics and Molecular biology are his primary areas of study. His study in Cell biology is interdisciplinary in nature, drawing from both Cell potency, Regulation of gene expression, Transcription factor and Epigenetics. His study explores the link between Transcription factor and topics such as Chromatin immunoprecipitation that cross with problems in Binding site.

His Induced pluripotent stem cell study which covers Reprogramming that intersects with Induced stem cells and Somatic cell. In his research, RNA interference and Bioinformatics is intimately related to Computational biology, which falls under the overarching field of Genetics. His Homeobox protein NANOG research incorporates elements of SOX2, Nanog Homeobox Protein, Enhancer and Rex1.

He most often published in these fields:

  • Cell biology (60.82%)
  • Embryonic stem cell (54.39%)
  • Induced pluripotent stem cell (45.61%)

What were the highlights of his more recent work (between 2015-2020)?

  • Cell biology (60.82%)
  • Induced pluripotent stem cell (45.61%)
  • Organoid (5.85%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Induced pluripotent stem cell, Organoid, Neuroscience and Embryonic stem cell. His Cell biology study combines topics from a wide range of disciplines, such as Transcriptome and Pathology. His Induced pluripotent stem cell research includes themes of Alkaline phosphatase, Parkinson's disease, Anatomy and Neuroepithelial cell.

His work carried out in the field of Embryonic stem cell brings together such families of science as Cellular differentiation, Cholangiocyte and Transfection. His studies deal with areas such as Clinical trial, Homeobox protein NANOG, Inner cell mass and Disease as well as Cellular differentiation. He has included themes like Molecular biology and Reprogramming in his Chromatin study.

Between 2015 and 2020, his most popular works were:

  • Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons (301 citations)
  • The metabolic programming of stem cells. (104 citations)
  • Outbreak of Zika virus infection in Singapore: an epidemiological, entomological, virological, and clinical analysis (89 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Gene expression

Huck-Hui Ng mostly deals with Neuroscience, Genetics, Human genome, Genome and Alternative splicing. His research integrates issues of Transplantation and Neural stem cell in his study of Neuroscience. His Neural stem cell study combines topics in areas such as Induced pluripotent stem cell and Anatomy.

His studies in Induced pluripotent stem cell integrate themes in fields like Substantia nigra, Cellular differentiation and Organoid. The concepts of his Anatomy study are interwoven with issues in Embryonic stem cell, Synapse, Neuromelanin and Cell biology. His work is connected to Gene, Endogenous retrovirus, Retrotransposon, Regulation of gene expression and Gene silencing, as a part of Genetics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

Xinsheng Nan;Huck-Hui Ng;Colin A. Johnson;Carol D. Laherty.
Nature (1998)

4083 Citations

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells.

Yuin Han Loh;Qiang Wu;Joon Lin Chew;Joon Lin Chew;Vinsensius B. Vega.
Nature Genetics (2006)

2870 Citations

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

Xi Chen;Han Xu;Ping Yuan;Fang Fang;Fang Fang.
Cell (2008)

2807 Citations

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

Yi Zhang;Huck-Hui Ng;Hediye Erdjument-Bromage;Paul Tempst.
Genes & Development (1999)

1430 Citations

A global map of p53 transcription-factor binding sites in the human genome.

Chia-Lin Wei;Qiang Wu;Vinsensius B. Vega;Kuo Ping Chiu.
Cell (2006)

1392 Citations

Transcriptional regulation of nanog by OCT4 and SOX2.

David J. Rodda;Joon-Lin Chew;Joon-Lin Chew;Leng-Hiong Lim;Yuin-Han Loh;Yuin-Han Loh.
Journal of Biological Chemistry (2005)

1372 Citations

Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity

Huck Hui Ng;François Robert;Richard A. Young;Kevin Struhl.
Molecular Cell (2003)

1338 Citations

Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

Linda S.-H. Chuang;Hang-In Ian;Tong-Wey Koh;Huck-Hui Ng.
Science (1997)

1172 Citations

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex.

Huck-Hui Ng;Yi Zhang;Brian Hendrich;Colin A Johnson.
Nature Genetics (1999)

1141 Citations

Methylation of H3-Lysine 79 Is Mediated by a New Family of HMTases without a SET Domain

Qin Feng;Hengbin Wang;Huck Hui Ng;Hediye Erdjument-Bromage.
Current Biology (2002)

935 Citations

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