2022 - Research.com Genetics and Molecular Biology in Singapore Leader Award
Huck-Hui Ng mainly investigates Cell biology, SOX2, Chromatin immunoprecipitation, Genetics and Transcription factor. His research in Cell biology focuses on subjects like Embryonic stem cell, which are connected to Molecular biology. His SOX2 research is multidisciplinary, relying on both Reprogramming and Homeobox protein NANOG.
As a part of the same scientific family, he mostly works in the field of Chromatin immunoprecipitation, focusing on Nanog Homeobox Protein and, on occasion, Octamer Transcription Factor-3. As part of his studies on Transcription factor, he often connects relevant subjects like Rex1. The various areas that Huck-Hui Ng examines in his Stem cell study include Induced stem cells and Embryoid body.
Cell biology, Embryonic stem cell, Induced pluripotent stem cell, Genetics and Molecular biology are his primary areas of study. His study in Cell biology is interdisciplinary in nature, drawing from both Cell potency, Regulation of gene expression, Transcription factor and Epigenetics. His study explores the link between Transcription factor and topics such as Chromatin immunoprecipitation that cross with problems in Binding site.
His Induced pluripotent stem cell study which covers Reprogramming that intersects with Induced stem cells and Somatic cell. In his research, RNA interference and Bioinformatics is intimately related to Computational biology, which falls under the overarching field of Genetics. His Homeobox protein NANOG research incorporates elements of SOX2, Nanog Homeobox Protein, Enhancer and Rex1.
His scientific interests lie mostly in Cell biology, Induced pluripotent stem cell, Organoid, Neuroscience and Embryonic stem cell. His Cell biology study combines topics from a wide range of disciplines, such as Transcriptome and Pathology. His Induced pluripotent stem cell research includes themes of Alkaline phosphatase, Parkinson's disease, Anatomy and Neuroepithelial cell.
His work carried out in the field of Embryonic stem cell brings together such families of science as Cellular differentiation, Cholangiocyte and Transfection. His studies deal with areas such as Clinical trial, Homeobox protein NANOG, Inner cell mass and Disease as well as Cellular differentiation. He has included themes like Molecular biology and Reprogramming in his Chromatin study.
Huck-Hui Ng mostly deals with Neuroscience, Genetics, Human genome, Genome and Alternative splicing. His research integrates issues of Transplantation and Neural stem cell in his study of Neuroscience. His Neural stem cell study combines topics in areas such as Induced pluripotent stem cell and Anatomy.
His studies in Induced pluripotent stem cell integrate themes in fields like Substantia nigra, Cellular differentiation and Organoid. The concepts of his Anatomy study are interwoven with issues in Embryonic stem cell, Synapse, Neuromelanin and Cell biology. His work is connected to Gene, Endogenous retrovirus, Retrotransposon, Regulation of gene expression and Gene silencing, as a part of Genetics.
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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
Xinsheng Nan;Huck-Hui Ng;Colin A. Johnson;Carol D. Laherty.
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells.
Yuin Han Loh;Qiang Wu;Joon Lin Chew;Joon Lin Chew;Vinsensius B. Vega.
Nature Genetics (2006)
Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells
Xi Chen;Han Xu;Ping Yuan;Fang Fang;Fang Fang.
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
Yi Zhang;Huck-Hui Ng;Hediye Erdjument-Bromage;Paul Tempst.
Genes & Development (1999)
A global map of p53 transcription-factor binding sites in the human genome.
Chia-Lin Wei;Qiang Wu;Vinsensius B. Vega;Kuo Ping Chiu.
Transcriptional regulation of nanog by OCT4 and SOX2.
David J. Rodda;Joon-Lin Chew;Joon-Lin Chew;Leng-Hiong Lim;Yuin-Han Loh;Yuin-Han Loh.
Journal of Biological Chemistry (2005)
Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity
Huck Hui Ng;François Robert;Richard A. Young;Kevin Struhl.
Molecular Cell (2003)
Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1
Linda S.-H. Chuang;Hang-In Ian;Tong-Wey Koh;Huck-Hui Ng.
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex.
Huck-Hui Ng;Yi Zhang;Brian Hendrich;Colin A Johnson.
Nature Genetics (1999)
Methylation of H3-Lysine 79 Is Mediated by a New Family of HMTases without a SET Domain
Qin Feng;Hengbin Wang;Huck Hui Ng;Hediye Erdjument-Bromage.
Current Biology (2002)
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