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Douglas E. Williams

Douglas E. Williams

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
15672
World Ranking
14817
National Ranking
6198

Overview

Douglas E. Williams is affiliated with Codiak BioSciences in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a particular emphasis on molecular biology and immunology. Their work encompasses various subfields including pulmonary and respiratory medicine, immunology and allergy, and cancer research.

The main topics explored in their publications include extracellular vesicles in disease, cell adhesion molecules research, microRNA in disease regulation, interferon and immune responses, inflammasome and immune disorders, immunotherapy and immune responses, and RNA interference and gene delivery.

Among their recent papers are the following:

  • A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties, 2021, Molecular Therapy
  • ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance, 2021, Communications Biology
  • Exosome Surface Display of IL12 Results in Tumor-Retained Pharmacology with Superior Potency and Limited Systemic Exposure Compared with Recombinant IL12, 2020, Molecular Cancer Therapeutics
  • In vivo tracking of [89Zr]Zr-labeled engineered extracellular vesicles by PET reveals organ-specific biodistribution based upon the route of administration, 2022, Nuclear Medicine and Biology
  • 709 Exosome surface display of IL-12 results in tumor-retained pharmacology with superior potency and limited systemic exposure, 2020, Regular and Young Investigator Award Abstracts

Frequent publication venues for Douglas E. Williams include:

  • Molecular Therapy
  • Communications Biology
  • Molecular Cancer Therapeutics
  • Nuclear Medicine and Biology
  • Regular and Young Investigator Award Abstracts

Frequent co-authors collaborating with them are:

  • Kevin Dooley
  • Su Chul Jang
  • Kyriakos D. Economides
  • Nuruddeen D. Lewis
  • Chang Ling Sia

Best Publications

  • Identification of a ligand for the c-kit proto-oncogene.

    Douglas E. Williams;June Eisenman;Allison Baird;Charles Rauch

  • Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms.

    Dirk M. Anderson;Stewart D. Lyman;Allison Baird;Janis M. Wignall

  • Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles.

    Neal G. Copeland;Debra J. Gilbert;Brian C. Cho;Peter J. Donovan

  • Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells

    Stewart D. Lyman;Laura James;Tim Vanden Bos;Peter de Vries

  • The suppressive influences of human tumor necrosis factors on bone marrow hematopoietic progenitor cells from normal donors and patients with leukemia: synergism of tumor necrosis factor and interferon-gamma.

    H E Broxmeyer;D E Williams;L Lu;S Cooper

  • Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice

    Tsvee Lapidot;Francoise Pflumio;Monica Doedens;Barbara Murdoch

  • Requirement for mast cell growth factor for primordial germ cell survival in culture

    Susanna Dolci;Douglas E. Williams;Mary K. Ernst;James L. Resnick

  • A thymic stromal cell line supports in vitro development of surface IgM+ B cells and produces a novel growth factor affecting B and T lineage cells

    Friend Sl;Hosier S;Nelson A;Foxworthe D

  • Pleiotropic effects of the CD30 ligand on CD30-expressing cells and lymphoma cell lines

    Hans-JOrgen Gruss;Norman Boiani;Douglas E. Williams;Richard J. Armitage

  • Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains.

    Camilynn I. Brannan;Stewart D. Lyman;Douglas E. Williams;June Eisenman

  • Hematologic effects of flt3 ligand in vivo in mice.

    Kenneth Brasel;Hilary J. McKenna;Philip J. Morrissey;Keith Charrier

  • Molecular Cloning and Biological Characterization of a Novel Murine Lymphoid Growth Factor

    John E. Sims;Douglas E. Williams;Philip J. Morrissey;Kirsten Garka

  • Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase.

    A.D. Reith;C. Ellis;S.D. Lyman;D.M. Anderson

  • Altered metabolism of mast-cell growth factor (c-kit ligand) in cutaneous mastocytosis.

    B. J. Longley;G. S. Morganroth;L. Tyrrell;Tie Gang Ding

  • The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor.

    R Rottapel;M Reedijk;D E Williams;S D Lyman

  • Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells.

    Hal E. Broxmeyer;Scott Cooper;Li Lu;Giao Hangoc

  • The Steel factor.

    Douglas E. Williams;Peter de Vries;Anthony E. Namen;Michael B. Widmer

  • Characterization of thymic stromal-derived lymphopoietin (TSLP) in murine B cell development in vitro

    Robert J. Ray;Caren Furlonger;Douglas E. Williams;Christopher J. Paige

  • The effect of recombinant mast cell growth factor on purified murine hematopoietic stem cells.

    P de Vries;K A Brasel;J R Eisenman;A R Alpert

  • Enhanced hematopoietic activity of a human granulocyte/macrophage colony-stimulating factor-interleukin 3 fusion protein.

    Benson M. Curtis;Benson M. Curtis;Douglas E. Williams;Hal E. Broxmeyer;Joseph Dunn

Frequent Co-Authors

Hal E. Broxmeyer
Hal E. Broxmeyer Indiana University
Scott Cooper
Scott Cooper Indiana University
Stewart D. Lyman
Stewart D. Lyman Lyman BioPharma Consulting, LLC
Giao Hangoc
Giao Hangoc Indiana University
David Cosman
David Cosman Amgen (United States)
Thomas J. MacVittie
Thomas J. MacVittie University of Maryland, Baltimore
Dirk M. Anderson
Dirk M. Anderson Washington University in St. Louis
Paolo Arosio
Paolo Arosio ETH Zurich
John W. Belmont
John W. Belmont Baylor College of Medicine
Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center

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