The scientist’s investigation covers issues in Virology, Hepatitis C virus, NS5A, Viral replication and Virus. Mark Harris interconnects Mutation, Myristoylation and Biochemistry in the investigation of issues within Virology. As a part of the same scientific study, Mark Harris usually deals with the Hepatitis C virus, concentrating on In vitro and frequently concerns with Amantadine.
His biological study spans a wide range of topics, including Cancer research, NS5B, PI3K/AKT/mTOR pathway, Phosphoinositide 3-kinase and Molecular biology. Mark Harris has included themes like RNA, Signal transduction and AP-1 transcription factor in his Molecular biology study. His research in Virus tackles topics such as Replicon which are related to areas like Intracellular, Bafilomycin and Interferon.
Virology, Virus, Hepatitis C virus, Viral replication and NS5A are his primary areas of study. His Virology research incorporates themes from Molecular biology, Replicon and Subgenomic mRNA. The concepts of his Virus study are interwoven with issues in Gene and Cell biology.
His research on Hepatitis C virus also deals with topics like
His primary areas of study are Virology, Virus, Replicon, Hepatitis C virus and Viral replication. In the subject of general Virology, his work in Viral entry is often linked to Context, thereby combining diverse domains of study. His Virus research is multidisciplinary, relying on both RNA and Gene.
The Replicon study combines topics in areas such as RNA-dependent RNA polymerase and Foot-and-mouth disease virus. His work on NS5A as part of general Hepatitis C virus study is frequently linked to Antiviral therapy, therefore connecting diverse disciplines of science. His Viral replication study deals with In vitro intersecting with Anthranilic acid, Zika virus and RNA silencing.
Mark Harris spends much of his time researching Virology, Virus, Replicon, Embolization and Viral replication. His Virology research includes elements of Luciferase and Pathogen. His research in Replicon intersects with topics in Internal ribosome entry site and Foot-and-mouth disease virus, Aphthovirus.
His study in Viral replication is interdisciplinary in nature, drawing from both RNA and Hepatitis C virus. While the research belongs to areas of RNA, Mark Harris spends his time largely on the problem of Cell biology, intersecting his research to questions surrounding NS5A. His work carried out in the field of Hepatitis C virus brings together such families of science as Phenotype and Molecular biology.
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The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine.
Stephen D.C. Griffin;Lucy P. Beales;Dean S. Clarke;Oliver Worsfold.
FEBS Letters (2003)
Hepatitis C virus NS5A: tales of a promiscuous protein.
Andrew Macdonald;Mark Harris.
Journal of General Virology (2004)
The Hepatitis C Virus NS5A Protein Activates a Phosphoinositide 3-Kinase-dependent Survival Signaling Cascade
Andrew Street;Andrew Macdonald;Katherine Crowder;Mark Harris.
Journal of Biological Chemistry (2004)
A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondria.
Stephen D. C. Griffin;Ruth Harvey;Dean S. Clarke;Wendy S. Barclay.
Journal of General Virology (2004)
Intracellular Proton Conductance of the Hepatitis C Virus p7 Protein and Its Contribution to Infectious Virus Production
Ann L. Wozniak;Stephen Griffin;Stephen Griffin;David Rowlands;Mark Harris.
PLOS Pathogens (2010)
Physical and Functional Interaction of Nef with Lck HIV-1 Nef-INDUCED T-CELL SIGNALING DEFECTS
Y. Collette;H. Dutartre;A. Benziane;F. Ramos-Morales.
Journal of Biological Chemistry (1996)
Identification of the Nef-associated kinase as p21-activated kinase 2.
G.Herma Renkema;Aki Manninen;Derek A. Mann;Mark Harris.
Current Biology (1999)
Construction of genetically engineered baculovirus insecticides containing the Bacillus thuringiensis subsp. kurstaki HD-73 delta endotoxin.
Alison T. Merryweather;Ulrike Weyer;Mark P. G. Harris;Mark Hirst.
Journal of General Virology (1990)
The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signaling
Andrew Macdonald;Katherine Crowder;Andrew Street;Christopher McCormick.
Journal of Biological Chemistry (2003)
HIV-1 Nef Induces the Release of Inflammatory Factors from Human Monocyte/Macrophages: Involvement of Nef Endocytotic Signals and NF-κB Activation
Eleonora Olivetta;Zulema Percario;Gianna Fiorucci;Gianfranco Mattia;Gianfranco Mattia.
Journal of Immunology (2003)
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