Kalle Saksela

Overview

Best Publications

• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

  Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  10661
  Citations

• Crystal Structure of the Conserved Core of HIV-1 Nef Complexed with a Src Family SH3 Domain

  Chi-Hon Lee;Kalle Saksela;Urooj A Mirza;Brian T Chait

  572
  Citations

• A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein

  Chi Hon Lee;Benjamin Leung;Mark A. Lemmon;Jie Zheng

  368
  Citations

• SH3 domain ligand binding: What's the consensus and where's the specificity?

  Kalle Saksela;Perttu Permi

  270
  Citations

• Harnessing Endogenous miRNAs to Control Virus Tissue Tropism as a Strategy for Developing Attenuated Virus Vaccines

  Dwight Barnes;Mark Kunitomi;Marco Vignuzzi;Kalle Saksela

  217
  Citations

• The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signaling

  Andrew Macdonald;Katherine Crowder;Andrew Street;Christopher McCormick

  197
  Citations

• High-throughput phosphotyrosine profiling using SH2 domains.

  Kazuya Machida;Christopher M. Thompson;Kevin Dierck;Karl Jablonowski

  197
  Citations

• Generation of a Conditionally Replicating Adenovirus Based on Targeted Destruction of E1A mRNA by a Cell Type-Specific MicroRNA

  Erkko Ylösmäki;Tanja Hakkarainen;Akseli Hemminki;Tapio Visakorpi

  194
  Citations

• myc oncogenes: activation and amplification

  Kari Alitalo;Päivi Koskinen;Tomi P. Mäkelä;Kalle Saksela

  193
  Citations

• Identification of the Nef-associated kinase as p21-activated kinase 2.

  G.Herma Renkema;Aki Manninen;Derek A. Mann;Mark Harris

  186
  Citations

• SH3 Domain-Mediated Recruitment of Host Cell Amphiphysins by Alphavirus nsP3 Promotes Viral RNA Replication

  Maarit Neuvonen;Arunas Kazlauskas;Miika Martikainen;Ari Hinkkanen

  179
  Citations

• Identification of preferred protein interactions by phage‐display of the human Src homology‐3 proteome

  Satu Kärkkäinen;Marita Hiipakka;Jing-Huan Wang;Iivari Kleino

  169
  Citations

• Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling.

  Leena S. Heikkinen;Arunas Kazlauskas;Krister Melén;Ralf Wagner

  148
  Citations

• Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation.

  Didier F. Vingadassalom;Arunas Kazlauskas;Brian M. Skehan;Hui-Chun Cheng

  144
  Citations

• SH3-Domain Binding Function of HIV-1 Nef Is Required for Association with a PAK-Related Kinase

  Aki Manninen;Marita Hiipakka;Mauno Vihinen;Wange Lu

  140
  Citations

• T cell circuits that sense antigen density with an ultrasensitive threshold

  Rogelio A. Hernandez-Lopez;Wei Yu;Katelyn A. Cabral;Olivia A. Creasey

  134
  Citations

• Acute myelogenous leukaemia with c-myc amplification and double minute chromosomes.

  Kari Alitalo;Robert Winqvist;Jorma Keski-Oja;Mirja Ilvonen

  124
  Citations

• Primary cutaneous T-cell lymphomas show a deletion or translocation affecting NAV3, the human UNC-53 homologue.

  Leena Karenko;Sonja Hahtola;Suvi Päivinen;Ritva Karhu

  122
  Citations

• Heat shock protects WEHI‐164 target cells from the cytolysis by tumor necrosis factors α and β

  Marja Jäättelä;Kalle Saksela;Eero Saksela

  114
  Citations

• HIV Nef, Paxillin, and Pak1/2 Regulate Activation and Secretion of TACE/ADAM10 Proteases

  Jung Hyun Lee;Sebastian Wittki;Tanja Bräu;Florian S. Dreyer

  108
  Citations