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Microbiology

D-Index
50
Citations
9427
World Ranking
4436
National Ranking
1715

Overview

Benjamin M. Segal is affiliated with The Ohio State University in the United States. Their research primarily focuses on the fields of Medicine and Neuroscience, with a notable emphasis on subfields such as Neurology, Immunology, Pathology and Forensic Medicine, Molecular Biology, and Rheumatology.

The main topics of Segal's work include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Multiple Sclerosis Research Studies
  • Systemic Lupus Erythematosus Research
  • Immunotherapy and Immune Responses
  • Neurogenesis and neuroplasticity mechanisms
  • Nerve injury and regeneration
  • S100 Proteins and Annexins

Benjamin M. Segal has contributed to multiple research papers published in various scientific journals. Some recent papers include:

  • "A new neutrophil subset promotes CNS neuron survival and axon regeneration," 2020, Nature Immunology
  • "Ageing and multiple sclerosis," 2022, The Lancet Neurology
  • "Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement," 2020, eLife
  • "Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα-mediated lipid metabolism," 2020, Journal of Clinical Investigation
  • "Chemokine receptor CXCR3 is required for lethal brain pathology but not pathogen clearance during cryptococcal meningoencephalitis," 2020, Science Advances

Frequent co-authors collaborating with Segal include:

  • Jeffrey Atkinson
  • Andrew Sas
  • Andrew Jerome
  • Tirisham Gyang
  • Kevin Carbajal

Segal has published often in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • SSRN Electronic Journal
  • The Journal of Immunology
  • Frontiers in Immunology
  • Nature Immunology

Best Publications

  • An Interleukin (IL)-10/IL-12 Immunoregulatory Circuit Controls Susceptibility to Autoimmune Disease

    Benjamin M. Segal;Bonnie K. Dwyer;Ethan M. Shevach

  • IL-12– and IL-23–modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition

    Mark A. Kroenke;Thaddeus J. Carlson;Anuska V. Andjelkovic;Benjamin M. Segal

  • Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease

    Irah L. King;Travis L. Dickendesher;Benjamin M. Segal

  • Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study

    Benjamin M Segal;Cris S Constantinescu;Aparna Raychaudhuri;Lilianne Kim

  • The Th17-ELR+ CXC Chemokine Pathway Is Essential for the Development of Central Nervous System Autoimmune Disease

    Thaddeus Carlson;Mark Kroenke;Praveen Rao;Thomas E. Lane

  • Neutrophil-related factors as biomarkers in EAE and MS

    Julie M. Rumble;Amanda K. Huber;Gurumoorthy Krishnamoorthy;Ashok Srinivasan

  • IL-12 unmasks latent autoimmune disease in resistant mice.

    Benjamin M. Segal;Ethan M. Shevach

  • Increased rejection of primary tumors in mice lacking B cells: Inhibition of anti‐tumor CTL and TH1 cytokine responses by B cells

    Sangeeta Shah;Anagha A. Divekar;Shannon P. Hilchey;Hyun Mi Cho

  • GM-CSF–dependent, CD103+ dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization

    Irah L. King;Mark A. Kroenke;Benjamin M. Segal

  • Microbial products induce autoimmune disease by an IL-12-dependent pathway.

    Benjamin M. Segal;Dennis M. Klinman;Ethan M. Shevach

  • A new neutrophil subset promotes CNS neuron survival and axon regeneration

    Andrew R. Sas;Andrew R. Sas;Andrew R. Sas;Kevin S. Carbajal;Andrew D. Jerome;Andrew D. Jerome;Rajasree Menon

  • CpG Oligonucleotides Are Potent Adjuvants for the Activation of Autoreactive Encephalitogenic T Cells In Vivo

    Benjamin M. Segal;John T. Chang;John T. Chang;Ethan M. Shevach

  • Ageing and multiple sclerosis

    Unknown

  • The costimulatory effect of IL-18 on the induction of antigen-specific IFN-γ production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor β2 subunit

    John T. Chang;Benjamin M. Segal;Kenji Nakanishi;Haruki Okamura

  • Activation of APCs through CD40 or Toll-like receptor 9 overcomes tolerance and precipitates autoimmune disease.

    Hiroshi T. Ichikawa;Lucas P. Williams;Benjamin M. Segal

  • Neuroinflammation triggered by β-glucan/dectin-1 signaling enables CNS axon regeneration

    Katherine T. Baldwin;Kevin S. Carbajal;Benjamin M. Segal;Roman J. Giger

  • T(H)17 cytokines in autoimmune neuro-inflammation.

    Burkhard Becher;Benjamin M Segal

  • Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.

    Ashley L Kalinski;Choya Yoon;Lucas D Huffman;Patrick C Duncker

  • Experimental autoimmune encephalomyelitis.

    Praveen Rao;Benjamin M Segal

  • CXC Chemokine Ligand 13 Plays a Role in Experimental Autoimmune Encephalomyelitis

    Ludmila V. Bagaeva;Praveen Rao;James M. Powers;Benjamin M. Segal

  • Regulation of Interleukin (IL)-12 Receptor β2 Subunit Expression by Endogenous IL-12: A Critical Step in the Differentiation of Pathogenic Autoreactive T Cells

    John T. Chang;Ethan M. Shevach;Benjamin M. Segal

  • Th17 cells in autoimmune demyelinating disease

    Benjamin Matthew Segal

Frequent Co-Authors

Ethan M. Shevach
Ethan M. Shevach National Institute of Allergy and Infectious Diseases
Ronald D. Chervin
Ronald D. Chervin University of Michigan–Ann Arbor
Olaf Stüve
Olaf Stüve The University of Texas Southwestern Medical Center
Roman J. Giger
Roman J. Giger University of Michigan–Ann Arbor
John T. Chang
John T. Chang University of California, San Diego
Joseph D. Rosenblatt
Joseph D. Rosenblatt University of Miami
Thomas E. Lane
Thomas E. Lane University of California, Irvine
Paul E. Sawchenko
Paul E. Sawchenko Salk Institute for Biological Studies
Daniel H. Geschwind
Daniel H. Geschwind University of California, Los Angeles
Philip L. De Jager
Philip L. De Jager Columbia University

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