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Immunology

D-Index
55
Citations
12555
World Ranking
3792
National Ranking
334

Overview

Bruno Gran is affiliated with the University of Nottingham in the United Kingdom and has a research focus primarily within the field of Medicine, contributing to 53 publications. Their subfields include Pathology and Forensic Medicine, Immunology, Oncology, Genetics, and Physiology.

The main topics of Bruno Gran's research work include:

  • Multiple Sclerosis Research Studies
  • Polyomavirus and related diseases
  • Viral-associated cancers and disorders
  • T-cell and B-cell Immunology
  • Dementia and Cognitive Impairment Research
  • Alzheimer's disease research and treatments
  • Parasites and Host Interactions

Bruno Gran has collaborated frequently with several co-authors, notably:

  • Radu Tănăsescu
  • Cris S. Constantinescu
  • Nanci Frakich
  • Emma Tallantyre
  • Helen Ford

Their recent papers cover a range of topics related to neurological and immunological research. These include:

  • "Hookworm Treatment for Relapsing Multiple Sclerosis," 2020, JAMA Neurology
  • "The Potential for EBV Vaccines to Prevent Multiple Sclerosis," 2022, Frontiers in Neurology
  • "CCN3 is dynamically regulated by treatment and disease state in multiple sclerosis," 2020, Journal of Neuroinflammation
  • "PAF-R on activated T cells: Role in the IL-23/Th17 pathway and relevance to multiple sclerosis," 2020, Immunobiology
  • "Increased IL-2 and Reduced TGF-β Upon T-Cell Stimulation are Associated with GM-CSF Upregulation in Multiple Immune Cell Types in Multiple Sclerosis," 2020, Biomedicines

Bruno Gran's work has been published in multiple venues, with several publications appearing particularly in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Diabetes
  • Frontiers in Neurology
  • Practical Neurology
  • Alzheimer's & Dementia

Best Publications

  • Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

    Cris S Constantinescu;Nasr Farooqi;Kate O'Brien;Bruno Gran

  • Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand.

    Bibiana Bielekova;Bonnie Goodwin;Nancy Richert;Irene Cortese

  • Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27–stimulated T cells

    Denise C Fitzgerald;Guang-Xian Zhang;Mohamed El-Behi;Zoë Fonseca-Kelly

  • IL-12p35-Deficient Mice Are Susceptible to Experimental Autoimmune Encephalomyelitis: Evidence for Redundancy in the IL-12 System in the Induction of Central Nervous System Autoimmune Demyelination

    Bruno Gran;Guang-Xian Zhang;Shuo Yu;Jifen Li

  • Induction of Experimental Autoimmune Encephalomyelitis in IL-12 Receptor-β2-Deficient Mice: IL-12 Responsiveness Is Not Required in the Pathogenesis of Inflammatory Demyelination in the Central Nervous System

    Guang-Xian Zhang;Bruno Gran;Shuo Yu;Jifen Li

  • Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase of experimental autoimmune encephalomyelitis.

    Denise C. Fitzgerald;Bogoljub Ciric;Tarik Touil;Heather Harle

  • IDO upregulates regulatory T cells via tryptophan catabolite and suppresses encephalitogenic T cell responses in experimental autoimmune encephalomyelitis

    Yaping Yan;Guang Xian Zhang;Bruno Gran;Francesca Fallarino

  • Fatigue in multiple sclerosis — A brief review

    Isuru Induruwa;Cris S. Constantinescu;Bruno Gran

  • Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease.

    Bernhard Hemmer;Bruno Gran;Yingdong Zhao;Adriana Marques

  • Mechanisms of immunomodulation by glatiramer acetate.

    B. Gran;L. R. Tranquill;M. Chen;B. Bielekova

  • TLR2 stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function.

    Mukanthu H. Nyirenda;Lara Sanvito;Peter J. Darlington;Kate O’Brien

  • Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia

    Yonghai Li;Niansheng Chu;Aihua Hu;Bruno Gran

  • Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells

    Felix J. Hartmann;Mohsen Khademi;Jehan Aram;Sandra Ammann

  • Cutting Edge: Predictable TCR Antigen Recognition Based on Peptide Scans Leads to the Identification of Agonist Ligands with No Sequence Homology

    Bernhard Hemmer;Marco Vergelli;Bruno Gran;Nick Ling

  • Cutting edge: TLR3 stimulation suppresses experimental autoimmune encephalomyelitis by inducing endogenous IFN-β

    Tarik Touil;Denise Fitzgerald;Guang-Xian Zhang;Abdoiniobaniad Rostami

  • EAE : imperfect but useful models of multiple sclerosis

    Bert A. ’t Hart;Bruno Gran;Robert Weissert

  • Molecular mimicry and multiple sclerosis: degenerate T-cell recognition and the induction of autoimmunity.

    Bruno Gran;Bernhard Hemmer;Marco Vergelli;Henry F. McFarland

  • Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders.

    Paolo A. Muraro;Klaus Peter Wandinger;Bibiana Bielekova;Bruno Gran

  • Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells.

    L. Jean-Gilles;M. Braitch;M. L. Latif;J. Aram

  • Glatiramer acetate induces a Th2-biased response and crossreactivity with myelin basic protein in patients with MS.

    M Chen;B Gran;K Costello;K Johnson

  • Exploring immunological specificity using synthetic peptide combinatorial libraries

    Clemencia Pinilla;Roland Martin;Bruno Gran;Jon R. Appel

Frequent Co-Authors

Abdolmohamad Rostami
Abdolmohamad Rostami Thomas Jefferson University
Roland Martin
Roland Martin University of Zurich
Bernhard Hemmer
Bernhard Hemmer Technical University of Munich
Henry F. McFarland
Henry F. McFarland National Institutes of Health
Bert A. 't Hart
Bert A. 't Hart University of Amsterdam
Clemencia Pinilla
Clemencia Pinilla Florida International University
Malek Kamoun
Malek Kamoun University of Pennsylvania
Amit Bar-Or
Amit Bar-Or University of Pennsylvania
Richard A. Houghten
Richard A. Houghten Florida International University
Francesca Fallarino
Francesca Fallarino University of Perugia

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