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Biology and Biochemistry

D-Index
55
Citations
8836
World Ranking
15250
National Ranking
6371

Overview

Malek Kamoun is affiliated with the University of Pennsylvania in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a focus on subfields such as Immunology, Transplantation, Surgery, Hematology, and Epidemiology.

Kamoun's work extensively covers topics related to transplantation and immunology. Main topics of their research include:

  • Renal Transplantation Outcomes and Treatments
  • T-cell and B-cell Immunology
  • Transplantation: Methods and Outcomes
  • Immune Cell Function and Interaction
  • Mechanical Circulatory Support Devices
  • Immunotherapy and Immune Responses
  • Hematopoietic Stem Cell Transplantation

They have contributed to frequent publication venues including:

  • Human Immunology
  • The Journal of Heart and Lung Transplantation
  • Transplantation and Cellular Therapy
  • American Journal of Transplantation
  • Transplant Immunology

Kamoun's recent papers demonstrate the scope of their research interests and findings. These publications include:

  • "Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes," 2020, American Journal of Transplantation
  • "BLyS neutralization results in selective anti-HLA alloantibody depletion without successful desensitization," 2021, Transplant Immunology
  • "The impact of HLA-DR mismatch status on retransplant-free survival and bronchiolitis obliterans syndrome-free survival among sensitized lung transplant recipients," 2020, The Journal of Heart and Lung Transplantation
  • "Deceased-Donor Acute Kidney Injury and Acute Rejection in Kidney Transplant Recipients: A Multicenter Cohort," 2022, American Journal of Kidney Diseases
  • "Genetics of HLA Peptide Presentation and Impact on Outcomes in HLA-Matched Allogeneic Hematopoietic Cell Transplantation," 2021, Transplantation and Cellular Therapy

The scientist collaborates regularly with several coauthors, prominently including:

  • Nicholas K. Brown
  • Ryan J. Urbanowicz
  • Loren Gragert
  • Jane Kearns
  • Andrew Courtwright

Best Publications

  • IL-12p35-Deficient Mice Are Susceptible to Experimental Autoimmune Encephalomyelitis: Evidence for Redundancy in the IL-12 System in the Induction of Central Nervous System Autoimmune Demyelination

    Bruno Gran;Guang-Xian Zhang;Shuo Yu;Jifen Li

  • Identification of a human T lymphocyte surface protein associated with the E-rosette receptor.

    M Kamoun;P J Martin;J A Hansen;M A Brown

  • Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells.

    Marek Kubin;Malek Kamoun;Giorgio Trinchieri

  • Induction of Experimental Autoimmune Encephalomyelitis in IL-12 Receptor-β2-Deficient Mice: IL-12 Responsiveness Is Not Required in the Pathogenesis of Inflammatory Demyelination in the Central Nervous System

    Guang-Xian Zhang;Bruno Gran;Shuo Yu;Jifen Li

  • Erythrophagocytic Tγ Lymphoma

    Marshall E. Kadin;Malek Kamoun;John Lamberg

  • Race and electronically measured adherence to immunosuppressive medications after deceased donor renal transplantation.

    Francis L. Weng;Ajay K. Israni;Marshall M. Joffe;Tracey Hoy

  • Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells.

    U Siebenlist;D B Durand;P Bressler;N J Holbrook

  • Antibody and B7/BB1-mediated ligation of the CD28 receptor induces tyrosine phosphorylation in human T cells.

    Peter Vandenberghe;Gordon J. Freeman;Lee M. Nadler;Mary C. Fletcher

  • Stimulation of Fc gamma RIIIA results in phospholipase C-gamma 1 tyrosine phosphorylation and p56lck activation.

    L Azzoni;M Kamoun;T W Salcedo;P Kanakaraj

  • A novel human T cell antigen preferentially expressed on mature T cells and shared by both well and poorly differentiated B cell leukemias and lymphomas.

    M Kamoun;M E Kadin;P J Martin;J Nettleton

  • Arginine at positions 13 or 70-71 in pocket 4 of HLA-DRB1 alleles is associated with susceptibility to tuberculoid leprosy.

    L. Zerva;B. Cizman;N. K. Mehra;S. K. Alahari

  • Role of IL-12 Receptor β1 in Regulation of T Cell Response by APC in Experimental Autoimmune Encephalomyelitis

    Guang-Xian Zhang;Shuo Yu;Bruno Gran;Jifen Li

  • Differential expression and regulation of IL-23 and IL-12 subunits and receptors in adult mouse microglia.

    Jifen Li;Bruno Gran;Guang Xian Zhang;Elvira S Ventura

  • Phosphatidylinositol-3 kinase activation induced upon Fc gamma RIIIA-ligand interaction.

    P Kanakaraj;B Duckworth;L Azzoni;M Kamoun

  • Improvement in β-Cell Secretory Capacity After Human Islet Transplantation According to the CIT07 Protocol

    Michael R. Rickels;Chengyang Liu;Richard D. Shlansky-Goldberg;Scott A. Soleimanpour

  • IL-27 subunits and its receptor (WSX-1) mRNAs are markedly up-regulated in inflammatory cells in the CNS during experimental autoimmune encephalomyelitis

    Jifen Li;Bruno Gran;Guang-Xian Zhang;Abdolmohamad Rostami

  • Cyclosporine augments receptor-mediated cellular Ca2+ fluxes in isolated hepatocytes.

    C V Nicchitta;M Kamoun;J R Williamson

  • Improving the antibody-based evaluation of autoimmune encephalitis.

    Lindsey McCracken;Junxian Zhang;Maxwell Greene;Anne Crivaro

  • Educating medical students in laboratory medicine: a proposed curriculum.

    Brian R. Smith;Maria Aguero-Rosenfeld;John Anastasi;Beverly Baron

  • C4d and C3d staining in biopsies of ABO- and HLA-incompatible renal allografts: correlation with histologic findings.

    Malek Kamoun

Frequent Co-Authors

Dimitri S. Monos
Dimitri S. Monos Children's Hospital of Philadelphia
Ali Naji
Ali Naji University of Pennsylvania
Eline T. Luning Prak
Eline T. Luning Prak University of Pennsylvania
Abdolmohamad Rostami
Abdolmohamad Rostami Thomas Jefferson University
James F. Markmann
James F. Markmann Harvard University
Ajay K. Israni
Ajay K. Israni University of Minnesota
Bruno Gran
Bruno Gran University of Nottingham
Howard M. Gebel
Howard M. Gebel Emory University
Harold I. Feldman
Harold I. Feldman University of Pennsylvania
John C. Reed
John C. Reed Johnson & Johnson (United States)

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