World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
72
Citations
17779
World Ranking
6328
National Ranking
2964

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Barbara E. Bierer is affiliated with Brigham and Women's Hospital in the United States. Their research primarily spans the field of Medicine, with a focused interest in Public Health, Environmental and Occupational Health, General Health Professions, Economics and Econometrics, Physiology, and Statistics, Probability and Uncertainty.

Their work concentrates on several main topics, including:

  • Ethics in Clinical Research
  • Health Systems, Economic Evaluations, Quality of Life
  • Biomedical Ethics and Regulation
  • Health and Medical Research Impacts
  • Ethics in Medical Practice
  • Meta-analysis and Systematic Reviews
  • Patient-Provider Communication in Healthcare

Barbara E. Bierer has published extensively in notable venues such as The American Journal of Bioethics, The Journal of Law Medicine & Ethics, Science, Journal of Clinical and Translational Science, and JAMA. The publication counts in these venues include seven papers each in The American Journal of Bioethics and The Journal of Law Medicine & Ethics, five in Science, four in Journal of Clinical and Translational Science, and four in JAMA.

Frequent collaborators in their work include Luke Gelinas, Sarah White, Sylvia Baedorf Kassis, Mark Barnes, and David H. Strauss, each contributing to multiple joint publications.

Several recent papers highlight contemporary research interests:

  • "Advancing the inclusion of underrepresented women in clinical research," 2022, Cell Reports Medicine
  • "Excluding People With Disabilities From Clinical Research: Eligibility Criteria Lack Clarity And Justification," 2022, Health Affairs
  • "IRBs and the Protection-Inclusion Dilemma: Finding a Balance," 2022, The American Journal of Bioethics
  • "Disruptive and avoidable: GDPR challenges to secondary research uses of data," 2020, European Journal of Human Genetics
  • "Time for NIH to lead on data sharing," 2020, Science

Notably, their research addresses ethical considerations in clinical research and health policy, including regulatory challenges and inclusivity in research populations.

Barbara E. Bierer has been recognized as a member of the Association of American Physicians.

Best Publications

  • Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A.

    David A. Fruman;Claude B. Klee;Barbara E. Bierer;Steven J. Burakoff

  • Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin.

    B E Bierer;P S Mattila;R F Standaert;L A Herzenberg

  • Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

    Daniel J. Price;J. Russell Grove;Victor Calvo;Joseph Avruch

  • Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations.

    Luke Gelinas;Robin Pierce;Sabune Winkler;I. Glenn Cohen

  • The Biologic Roles of CD2, CD4, and CD8 in T-Cell Activation

    B E Bierer;B P Sleckman;S E Ratnofsky;S J Burakoff

  • Probing immunosuppressant action with a nonnatural immunophilin ligand

    Barbara E. Bierer;Patricia K. Somers;Thomas J. Wandless;Steven J. Burakoff

  • Eb1 Proteins Regulate Microtubule Dynamics, Cell Polarity, and Chromosome Stability

    Jennifer S. Tirnauer;Barbara E. Bierer

  • Yeast Bim1p promotes the G1-specific dynamics of microtubules.

    Jennifer S. Tirnauer;Eileen O'Toole;Lisbeth Berrueta;Barbara E. Bierer

  • Immunophilins in protein folding and immunosuppression.

    David A. Fruman;Steven J. Burakoff;Barbara E. Bierer

  • CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1

    Yvonne Rosenstein;John K. Park;William C. Hahn;Fred S. Rosen

  • Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells

    Wen Chen Yeh;Barbara E. Bierer;Steven L. McKnight

  • CD28/CTLA-4 and CD80/CD86 families: signaling and function.

    Jacqueline M. Slavik;Jill E. Hutchcroft;Barbara E. Bierer

  • The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules

    Lisbeth Berrueta;Stine Katherine Kraeft;Jennifer S. Tirnauer;Scott C. Schuyler

  • Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology

    Barbara E. Bierer;Georg Holländer;David Fruman;Steven J. Burakoff

  • Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor.

    B E Bierer;A Peterson;J C Gorga;S H Herrmann

  • Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13.

    Yong-Jiu Jin;Mark W. Albers;William S. Lane;Barbara E. Bierer

  • Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin.

    Victor Calvo;Craig M. Crews;Terry A. Vik;Barbara E. Bierer

  • Rapamycin and FK506 binding proteins (immunophilins)

    Heinz Fretz;Mark W. Albers;Andrzej Galat;Robert F. Standaert

  • The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain.

    Lisbeth Berrueta;Jennifer S. Tirnauer;Scott C. Schuyler;David Pellman

  • Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation.

    S. J. Mentzer;E. Remold-O'donnell;M. A. V. Crimmins;B. E. Bierer

Frequent Co-Authors

Steven J. Burakoff
Steven J. Burakoff Icahn School of Medicine at Mount Sinai
David A. Fruman
David A. Fruman University of California, Irvine
William C. Hahn
William C. Hahn Dana-Farber Cancer Institute
I. Glenn Cohen
I. Glenn Cohen Harvard University
Joseph H. Antin
Joseph H. Antin Dana-Farber Cancer Institute
David E. Golan
David E. Golan Harvard Medical School
Stuart L. Schreiber
Stuart L. Schreiber Harvard University
Sung-Yun Pai
Sung-Yun Pai National Institutes of Health
Howard J. Weinstein
Howard J. Weinstein Harvard University
David Pellman
David Pellman Howard Hughes Medical Institute

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