World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
56
Citations
12970
World Ranking
3698
National Ranking
1703

Overview

Sung-Yun Pai is affiliated with the National Institutes of Health in the United States. Their research focuses primarily on medicine, immunology and microbiology, and biochemistry, genetics and molecular biology. Within these disciplines, Pai has contributed extensively to subfields such as immunology, genetics, epidemiology, hematology, and oncology.

The scientist's work centers on several main research topics, which include:

  • Immunodeficiency and Autoimmune Disorders
  • Cytomegalovirus and herpesvirus research
  • CAR-T cell therapy research
  • Virus-based gene therapy research
  • Hematopoietic Stem Cell Transplantation
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Blood disorders and treatments

The following frequent co-authors have collaborated with Pai in their scientific publications:

  • Luigi D. Notarangelo
  • Christopher C. Dvorak
  • Michael A. Pulsipher
  • Donald B. Kohn
  • Élie Haddad

Pai has published extensively across several notable scientific venues. The most frequent publication outlets include:

  • Blood
  • Transplantation and Cellular Therapy
  • Journal of Allergy and Clinical Immunology
  • Clinical Immunology
  • Blood Advances

Some of the recent papers authored or co-authored by Pai are:

  • Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease, 2020, New England Journal of Medicine
  • Lentiviral gene therapy for X-linked chronic granulomatous disease, 2020, Nature Medicine
  • Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report, 2020, Blood
  • The diagnosis of severe combined immunodeficiency (SCID): The Primary Immune Deficiency Treatment Consortium (PIDTC) 2022 Definitions, 2022, Journal of Allergy and Clinical Immunology
  • Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium, 2023, The Lancet

Best Publications

  • Transplantation Outcomes for Severe Combined Immunodeficiency, 2000–2009

    Sung Yun Pai;Brent R. Logan;Linda M. Griffith;Rebecca H. Buckley

  • Newborn Screening for Severe Combined Immunodeficiency in 11 Screening Programs in the United States

    Antonia Kwan;Roshini S. Abraham;Robert Currier;Amy Brower

  • Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation

    Ann M. Leen;Catherine M. Bollard;Adam M. Mendizabal;Elizabeth J. Shpall

  • GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation.

    I-Cheng Ho;Tzong-Shyuan Tai;Sung-Yun Pai

  • GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

    Sung-Yun Pai;Morgan L. Truitt;I-Cheng Ho

  • A Modified γ-Retrovirus Vector for X-Linked Severe Combined Immunodeficiency

    Salima Hacein-Bey-Abina;Sung Yun Pai;H. Bobby Gaspar;Myriam Armant

  • GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

    Hosein Kouros-Mehr;Seth K. Bechis;Euan M. Slorach;Laurie E. Littlepage

  • Critical Roles for Transcription Factor GATA-3 in Thymocyte Development

    Sung-Yun Pai;Morgan L Truitt;Chao-Nan Ting;Jeffrey M Leiden

  • Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease

    Erica B. Esrick;Leslie E. Lehmann;Alessandra Biffi;Maureen Achebe

  • Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study

    Daniele Moratto;Silvia Giliani;Carmem Bonfim;Evelina Mazzolari

  • Establishing diagnostic criteria for severe combined immunodeficiency disease (SCID), leaky SCID, and Omenn syndrome: The Primary Immune Deficiency Treatment Consortium experience

    William T. Shearer;Elizabeth Dunn;Luigi D. Notarangelo;Christopher C. Dvorak

  • DOCK8 Deficiency: Clinical and Immunological Phenotype and Treatment Options - a Review of 136 Patients

    Susanne E. Aydin;Sara Sebnem Kilic;Caner Aytekin;Ashish Kumar

  • Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study

    Federica Barzaghi;Laura Cristina Amaya Hernandez;Benedicte Neven;Silvia Ricci

  • Immune reconstitution and survival of 100 SCID patients post-hematopoietic cell transplant: a PIDTC natural history study.

    Jennifer Heimall;Brent R. Logan;Morton J. Cowan;Luigi D. Notarangelo

  • Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia

    Bertrand Boisson;Emmanuel Laplantine;Kerry Dobbs;Aurélie Cobat

  • Lentiviral gene therapy for X-linked chronic granulomatous disease.

    Donald B. Kohn;Claire Booth;Elizabeth M. Kang;Sung-Yun Pai

  • Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies

    Jodie Ouahed;Elizabeth Spencer;Daniel Kotlarz;Dror S Shouval

  • The syndrome of hemophagocytic lymphohistiocytosis in primary immunodeficiencies: implications for differential diagnosis and pathogenesis

    Sebastian Fn Bode;Sandra Ammann;Waleed Al-Herz;Mihaela Bataneant

  • Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis

    Hidenori Hattori;Kulandayan K. Subramanian;Jiro Sakai;Yonghui Jia

  • GATA-3 Regulates the Development and Function of Invariant NKT Cells

    Peter J. Kim;Sung-Yun Pai;Manfred Brigl;Manfred Brigl;Gurdyal S. Besra

  • Whole-exome sequencing identifies tetratricopeptide repeat domain 7A (TTC7A) mutations for combined immunodeficiency with intestinal atresias

    Rui Chen;Silvia Giliani;Gaetana Lanzi;George I. Mias

  • Human HOIP and LUBAC de!ciency underlies autoin"ammation, immunode!ciency, amylopectinosis, and lymphangiectasia

    Bertrand Boisson;Emmanuel Laplantine;Kerry Dobbs;Aurélie Cobat

Frequent Co-Authors

Luigi D. Notarangelo
Luigi D. Notarangelo National Institutes of Health
Morton J. Cowan
Morton J. Cowan University of California, San Francisco
Raif S. Geha
Raif S. Geha Boston Children's Hospital
Jennifer M. Puck
Jennifer M. Puck University of California, San Francisco
Donald B. Kohn
Donald B. Kohn University of California, Los Angeles
Jolan E. Walter
Jolan E. Walter University of South Florida
Waleed Al-Herz
Waleed Al-Herz Kuwait University
Elie Haddad
Elie Haddad University of Montreal
Andrew R. Gennery
Andrew R. Gennery Newcastle University
I-Cheng Ho
I-Cheng Ho Brigham and Women's Hospital

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