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Molecular Biology

D-Index
66
Citations
13037
World Ranking
1632
National Ranking
34

Overview

Claudio Sette is affiliated with the Catholic University of the Sacred Heart in Italy. Their research spans several fields within biochemistry, genetics, molecular biology, and medicine, with a primary focus on molecular biology and oncology.

The scholar's work encompasses a broad range of specialized subfields, including:

  • Molecular Biology
  • Oncology
  • Cancer Research
  • Genetics
  • Immunology

Main research topics include:

  • RNA Research and Splicing
  • RNA Modifications and Cancer
  • Pancreatic and Hepatic Oncology Research
  • Cancer Genomics and Diagnostics
  • Cancer-related Gene Regulation
  • RNA and Protein Synthesis Mechanisms
  • Cancer Cells and Metastasis

Claudio Sette has published extensively, with notable recent papers such as:

  • Intratumoral injection of TLR9 agonist promotes an immunopermissive microenvironment transition and causes cooperative antitumor activity in combination with anti-PD1 in pancreatic cancer, 2021, Journal for ImmunoTherapy of Cancer
  • Splicing regulation in brain and testis: common themes for highly specialized organs, 2021, Cell Cycle
  • The DNA/RNA helicase DHX9 contributes to the transcriptional program of the androgen receptor in prostate cancer, 2022, Journal of Experimental & Clinical Cancer Research
  • Oncogenic dysregulation of pre-mRNA processing by protein kinases: challenges and therapeutic opportunities, 2021, FEBS Journal
  • Patient-derived organoids and high grade serous ovarian cancer: from disease modeling to personalized medicine, 2021, Journal of Experimental & Clinical Cancer Research

Frequent co-authors working alongside Claudio Sette include:

  • Chiara Naro
  • Eleonora Cesari
  • Gabriele Capurso
  • Valentina Panzeri
  • Paolo Giorgio Arcidiacono

Publications by Claudio Sette appear regularly in established journals, notably:

  • Pancreatology
  • Journal of Experimental & Clinical Cancer Research
  • Cells
  • Nucleic Acids Research
  • Cellular and Molecular Life Sciences

Best Publications

  • Phosphorylation and Activation of a cAMP-specific Phosphodiesterase by the cAMP-dependent Protein Kinase INVOLVEMENT OF SERINE 54 IN THE ENZYME ACTIVATION

    Claudio Sette;Marco Conti

  • Recent Progress in Understanding the Hormonal Regulation of Phosphodiesterases

    Marco Conti;Georges Nemoz;Claudio Sette;Elena Vicini

  • The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x

    Maria Paola Paronetto;Tilman Achsel;Autumn Massiello;Autumn Massiello;Charles E. Chalfant;Charles E. Chalfant

  • EMT and stemness: flexible processes tuned by alternative splicing in development and cancer progression.

    Davide Pradella;Chiara Naro;Claudio Sette;Claudia Ghigna

  • Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition

    Jing Chen;Collin Melton;Nayoung Suh;Jeong Su Oh

  • The short-term activation of a rolipram-sensitive, cAMP-specific phosphodiesterase by thyroid-stimulating hormone in thyroid FRTL-5 cells is mediated by a cAMP-dependent phosphorylation.

    C Sette;S Iona;M Conti

  • Parthenogenetic activation of mouse eggs by microinjection of a truncated c-kit tyrosine kinase present in spermatozoa.

    Claudio Sette;Arturo Bevilacqua;Andrea Bianchini;Franco Mangia

  • Denervation-activated STAT3–IL-6 signalling in fibro-adipogenic progenitors promotes myofibres atrophy and fibrosis

    Luca Madaro;Magda Passafaro;David Sala;Usue Etxaniz

  • Role of c-kit in mammalian spermatogenesis.

    P. Rossi;C. Sette;S. Dolci;R. Geremia

  • Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound

    Maria Loiarro;Federica Capolunghi;Nicola Fantò;Grazia Gallo

  • Peptide-mediated Interference of TIR Domain Dimerization in MyD88 Inhibits Interleukin-1-dependent Activation of NF-κB *

    Maria Loiarro;Claudio Sette;Grazia Gallo;Andrea Ciacci

  • Modulation of PKM alternative splicing by PTBP1 promotes gemcitabine resistance in pancreatic cancer cells

    S Calabretta;S Calabretta;P Bielli;I Passacantilli;I Passacantilli;E Pilozzi

  • The role of stem cell factor and of alternative c-kit gene products in the establishment, maintenance and function of germ cells

    Claudio Sette;Susanna Dolci;Raffaele Geremia;Pellegrino Rossi

  • The RNA-binding protein Sam68 contributes to proliferation and survival of human prostate cancer cells

    R Busà;M P Paronetto;D Farini;E Pierantozzi

  • Sam68 regulates EMT through alternative splicing-activated nonsense-mediated mRNA decay of the SF2/ASF proto-oncogene.

    Cristina Valacca;Serena Bonomi;Emanuele Buratti;Simona Pedrotti

  • Dynamic Regulation of Histone H3 Methylation at Lysine 4 in Mammalian Spermatogenesis

    Maren Godmann;Veronik Auger;Vivian Ferraroni-Aguiar;Annarita Di Sauro

  • The RNA-binding protein Sam68 is a multifunctional player in human cancer

    Pamela Bielli;Roberta Busà;Maria Paola Paronetto;Claudio Sette

  • Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68.

    Maria Paola Paronetto;Manuela Cappellari;Roberta Busà;Simona Pedrotti

  • ACTIVATION AND SELECTIVE INHIBITION OF A CYCLIC AMP-SPECIFIC PHOSPHODIESTERASE, PDE-4D3

    R Alvarez;C Sette;D Yang;R M Eglen

  • The ratPDE3/IVd phosphodiesterase gene codes for multiple proteins differentially activated by cAMP-dependent protein kinase.

    Claudio Sette;Elena Vicini;Marco Conti

Frequent Co-Authors

Raffaele Geremia
Raffaele Geremia University of Rome Tor Vergata
Luca Battistini
Luca Battistini Albert Einstein College of Medicine
David J. Elliott
David J. Elliott Newcastle University
Rita Carsetti
Rita Carsetti Bambino Gesù Children's Hospital
Michel Lagarde
Michel Lagarde Institut National des Sciences Appliquées de Lyon
Gian Maria Fimia
Gian Maria Fimia Sapienza University of Rome
Renato Franco
Renato Franco University of Campania "Luigi Vanvitelli"
Monica Fedele
Monica Fedele National Research Council (CNR)
Diego Centonze
Diego Centonze University of Rome Tor Vergata
Alfredo Fusco
Alfredo Fusco University of Naples Federico II

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