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Biology and Biochemistry

D-Index
70
Citations
16038
World Ranking
7075
National Ranking
228

Overview

Michel Lagarde is affiliated with the Institut National des Sciences Appliquées de Lyon in France. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a focus on several interconnected subfields including Biochemistry, Nutrition and Dietetics, Molecular Biology, Surgery, and Pharmacology.

The body of work produced by Michel Lagarde extensively covers topics related to fatty acids, lipid metabolism, and their impact on health. Their main research interests can be grouped into the following topics:

  • Fatty Acid Research and Health
  • Lipid metabolism and biosynthesis
  • Eicosanoids and Hypertension Pharmacology
  • Neurological Disease Mechanisms and Treatments
  • Cancer, Lipids, and Metabolism
  • Cholesterol and Lipid Metabolism
  • Lipid Membrane Structure and Behavior

Michel Lagarde's recent publications include five notable papers published between 2020 and 2024, reflecting ongoing research into the relationship between lipids and brain health, inflammation, and metabolic processes. These papers are:

  • "Brain targeting with docosahexaenoic acid as a prospective therapy for neurodegenerative diseases and its passage across blood brain barrier," 2020, Biochimie
  • "Docosahexaenoic Acid (DHA) Bioavailability in Humans after Oral Intake of DHA-Containing Triacylglycerol or the Structured Phospholipid AceDoPC®," 2020, Nutrients
  • "Ischemic Brain Injury: Involvement of Lipids in the Pathophysiology of Stroke and Therapeutic Strategies," 2024, Antioxidants
  • "Anti-inflammatory and anti-virus potential of poxytrins, especially protectin DX," 2020, Biochimie
  • "Esterification of Docosahexaenoic Acid Enhances Its Transport to the Brain and Its Potential Therapeutic Use in Brain Diseases," 2022, Nutrients

The frequent collaborators working with Michel Lagarde include Nathalie Bernoud-Hubac, Amanda Lo Van, Mayssa Hachem, Mounir Belkouch, and Madeleine Picq. These collaborations indicate a multidisciplinary approach combining expertise in biochemistry, nutrition, and molecular biology to explore lipid-related mechanisms and therapies.

Michel Lagarde's work has been published in a range of scientific venues, with repeated contributions to journals such as Biochimie and Nutrients. Other publication venues include Antioxidants, the International Journal of Molecular Sciences, and Prostaglandins Leukotrienes and Essential Fatty Acids, showing a consistent focus on biochemistry and lipid research across various respected platforms.

Best Publications

  • Small, Dense High-Density Lipoprotein-3 Particles Are Enriched in Negatively Charged Phospholipids Relevance to Cellular Cholesterol Efflux, Antioxidative, Antithrombotic, Anti-Inflammatory, and Antiapoptotic Functionalities

    Laurent Camont;Marie Lhomme;Fabiana Rached;Wilfried Le Goff

  • Characterization of plasma unsaturated lysophosphatidylcholines in human and rat.

    Martine Croset;Nicole Brossard;Anne Polette;Michel Lagarde

  • Reaction of Metformin with Dicarbonyl Compounds. Possible Implication in the Inhibition of Advanced Glycation End Product Formation

    Daniel Ruggiero-Lopez;Marc Lecomte;Gérard Moinet;Gérard Patereau

  • Fatty Acid Substrate Specificities of Human Prostaglandin-endoperoxide H Synthase-1 and −2 FORMATION OF 12-HYDROXY-(9Z,13E/Z,15Z)-OCTADECATRIENOIC ACIDS FROM α-LINOLENIC ACID

    Odette Laneuville;Debra K. Breuer;Naxing Xu;Z.H. Huang

  • Lysophosphatidylcholine as a preferred carrier form of docosahexaenoic acid to the brain

    Michel Lagarde;Nathalie Bernoud;Nicole Brossard;Dominique Lemaitre-Delaunay

  • 13-Hydroxyoctadecadienoic acid is the vessel wall chemorepellant factor, LOX.

    M R Buchanan;T A Haas;M Lagarde;M Guichardant

  • Effects of oxidative stress on adiponectin secretion and lactate production in 3T3-L1 adipocytes.

    A.F. Soares;M. Guichardant;D. Cozzone;N. Bernoud-Hubac

  • A simple and efficient method for platelet isolation from their plasma

    M. Lagarde;P.A. Bryon;M. Guichardant;M. Dechavanne

  • Retroconversion and metabolism of [13C]22:6n-3 in humans and rats after intake of a single dose of [13C]22:6n-3-triacylglycerols

    N Brossard;M Croset;C Pachiaudi;J P Riou

  • Dietary oxidized n-3 PUFA induce oxidative stress and inflammation: role of intestinal absorption of 4-HHE and reactivity in intestinal cells

    Manar Awada;Manar Awada;Christophe O. Soulage;Anne Meynier;Cyrille Debard

  • Lipidomics is emerging.

    Michel Lagarde;Alain Géloën;Michel Record;Dennis Vance

  • Advanced glycation end-products induce apoptosis of bovine retinal pericytes in culture: involvement of diacylglycerol/ceramide production and oxidative stress induction

    Ulriche Denis;Marc Lecomte;Clarisse Paget;Daniel Ruggiero

  • Blood compartmental metabolism of docosahexaenoic acid (DHA) in humans after ingestion of a single dose of [13C]DHA in phosphatidylcholine

    Dominique Lemaitre-Delaunay;Christiane Pachiaudi;Martine Laville;Jérome Pousin

  • Increasing intakes of the long-chain ω-3 docosahexaenoic acid: effects on platelet functions and redox status in healthy men

    Nicolas Guillot;Emilie Caillet;Martine Laville;Catherine Calzada

  • Stereospecific inhibition of PGH2-induced platelet aggregation by lipoxygenase products of icosaenoic acids

    M. Croset;M. Lagarde

  • Editorial: What is lipidomics?

    Friedrich Spener;Michel Lagarde;Alain Géloên;Michel Record

  • Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation.

    Nadia Meskini;Georges Némoz;Ismahan Okyayuz-Baklouti;Michel Lagarde

  • Covalent modifications of aminophospholipids by 4-hydroxynonenal

    Michel Guichardant;Pascale Taibi-Tronche;Laurent B. Fay;Michel Lagarde

  • Activation of P38 mitogen-activated protein kinase/cytosolic phospholipase A2 cascade in hydroperoxide-stressed platelets

    Laurent Coulon;Catherine Calzada;Philippe Moulin;Evelyne Véricel

  • Diabetic patients without vascular complications display enhanced basal platelet activation and decreased antioxidant status.

    Evelyne Véricel;Caroline Januel;Martine Carreras;Philippe Moulin

Frequent Co-Authors

Romain A. Colas
Romain A. Colas Brigham and Women's Hospital
Hubert Vidal
Hubert Vidal Claude Bernard University Lyon 1
Toshihide Kobayashi
Toshihide Kobayashi University of Strasbourg
Yves Berthier
Yves Berthier Institut National des Sciences Appliquées de Lyon
Claudio Sette
Claudio Sette Catholic University of the Sacred Heart
Thierry Durand
Thierry Durand University of Montpellier
Leena Mykkänen
Leena Mykkänen The University of Texas Health Science Center at San Antonio
Ralph B. D'Agostino
Ralph B. D'Agostino Wake Forest University
Roméo Cecchelli
Roméo Cecchelli Artois University
Laurent B. Fay
Laurent B. Fay Nestlé (Switzerland)

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