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Neuroscience

D-Index
75
Citations
18153
World Ranking
2036
National Ranking
66

Overview

Sophie Layé is affiliated with the University of Bordeaux in France and has contributed significantly to research in Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology. Their work spans critical subfields such as Nutrition and Dietetics, Physiology, Molecular Biology, Neurology, and Biological Psychiatry.

Their research primarily focuses on topics including Fatty Acid Research and Health, Diet and Metabolism Studies, Neuroinflammation and Neurodegeneration Mechanisms, Tryptophan and Brain Disorders, Gut Microbiota and Health, Neuroscience and Neuropharmacology Research, and Receptor Mechanisms and Signaling.

Sophie Layé's recent papers reflect a wide range of interests and contributions in these areas. Key publications include:

  • "Microbiota-derived metabolites as drivers of gut-brain communication," 2022, Gut Microbes
  • "Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain," 2020, Nature Communications
  • "Perinatal Dietary Polyunsaturated Fatty Acids in Brain Development, Role in Neurodevelopmental Disorders," 2021, Nutrients
  • "Chronic Supplementation with a Mix of Salvia officinalis and Salvia lavandulaefolia Improves Morris Water Maze Learning in Normal Adult C57Bl/6J Mice," 2020, Nutrients
  • "Circulating Triglycerides Gate Dopamine-Associated Behaviors through DRD2-Expressing Neurons," 2020, Cell Metabolism

Their frequent publication venues provide insight into their active academic dissemination channels, including Nutrients, Brain Behavior and Immunity, bioRxiv (Cold Spring Harbor Laboratory), Nutrition Clinique et Métabolisme, and Cell Metabolism.

Sophie Layé collaborates regularly with a number of coauthors, including Corinne Joffre, Quentin Leyrolle, Anne-Laure Dinel, Xavier Fioramonti, and Véronique Pallet. These collaborations have contributed to advancing research within their shared fields of interest.

Best Publications

  • Polyunsaturated fatty acids and their metabolites in brain function and disease

    Richard P. Bazinet;Sophie Layé

  • Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice

    Sophie Layé;Patricia Parnet;Emmanuelle Goujon;Robert Dantzer

  • Microbiota-derived metabolites as drivers of gut–brain communication

    Unknown

  • Lipopolysaccharide induces sickness behaviour in rats by a vagal mediated mechanism.

    R. M. Bluthe;V. Walter;P. Parnet;S. Laye

  • Subdiaphragmatic vagotomy blocks induction of IL-1 beta mRNA in mice brain in response to peripheral LPS.

    S. Laye;R. M. Bluthe;S. Kent;C. Combe

  • Anti-Inflammatory Effects of Omega-3 Fatty Acids in the Brain: Physiological Mechanisms and Relevance to Pharmacology

    Sophie Layé;Agnès Nadjar;Corinne Joffre;Richard P. Bazinet

  • Chronic Low-Grade Inflammation in Elderly Persons Is Associated with Altered Tryptophan and Tyrosine Metabolism: Role in Neuropsychiatric Symptoms

    Lucile Capuron;Sebastian Schroecksnadel;Catherine Féart;Agnès Aubert

  • Cytokines and sickness behavior

    Robert Dantzer;Rose Marie Bluthé;Sophie Layé;Jean Luc Bret-Dibat

  • The neuroimmune basis of fatigue

    Robert Dantzer;Cobi Jacoba Johanna Heijnen;Annemieke Kavelaars;Sophie Laye

  • Impairment of hippocampal-dependent memory induced by juvenile high-fat diet intake is associated with enhanced hippocampal inflammation in rats.

    Chloé Boitard;Amandine Cavaroc;Julie Sauvant;Agnès Aubert

  • Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions

    Mathieu Lafourcade;Thomas Larrieu;Thomas Larrieu;Susana Mato;Anais Duffaud;Anais Duffaud

  • Role of interleukin‐1β and tumour necrosis factor‐α in lipopolysaccharide‐induced sickness behaviour: a study with interleukin‐1 type I receptor‐deficient mice

    Rose Marie Bluthé;Sophie Layé;Bruno Michaud;Chantal Combe

  • Molecular Basis of Sickness Behaviora

    Robert Dantzer;Rose Marie Bluthé;Gilles Gheusi;Sandrine Cremona

  • Cognitive and Emotional Alterations Are Related to Hippocampal Inflammation in a Mouse Model of Metabolic Syndrome

    Anne-Laure Dinel;Caroline André;Caroline André;Agnès Aubert;Agnès Aubert;Guillaume Ferreira;Guillaume Ferreira

  • Food for Mood: Relevance of Nutritional Omega-3 Fatty Acids for Depression and Anxiety.

    Thomas Larrieu;Sophie Layé

  • Diet-induced obesity progressively alters cognition, anxiety-like behavior and lipopolysaccharide-induced depressive-like behavior: focus on brain indoleamine 2,3-dioxygenase activation

    Caroline André;Anne-Laure Dinel;Guillaume Ferreira;Sophie Layé

  • Juvenile, but not adult exposure to high‐fat diet impairs relational memory and hippocampal neurogenesis in mice

    Chloe Boitard;Nicole Etchamendy;Nicole Etchamendy;Julie Sauvant;Julie Sauvant;Agnes Aubert;Agnes Aubert

  • Endogenous brain IL-1 mediates LPS-induced anorexia and hypothalamic cytokine expression

    Sophie Layé;Gilles Gheusi;Sandrine Cremona;Chantal Combe

  • Food for thought: how nutrition impacts cognition and emotion

    Sarah J. Spencer;Aniko Korosi;Sophie Layé;Barbara Shukitt-Hale

  • Short-Term Long Chain Omega3 Diet Protects from Neuroinflammatory Processes and Memory Impairment in Aged Mice

    Virginie F. Labrousse;Agnès Nadjar;Agnès Nadjar;Corinne Joffre;Corinne Joffre;Laurence Costes;Laurence Costes

  • Docosahexaenoic acid prevents lipopolysaccharide-induced cytokine production in microglial cells by inhibiting lipopolysaccharide receptor presentation but not its membrane subdomain localization.

    Véronique De Smedt-Peyrusse;Françoise Sargueil;Aurélie Moranis;Hedi Harizi

Frequent Co-Authors

Guillaume Ferreira
Guillaume Ferreira University of Bordeaux
Nathalie Castanon
Nathalie Castanon University of Bordeaux
Laurent Gautron
Laurent Gautron The University of Texas Southwestern Medical Center
Olivier J. Manzoni
Olivier J. Manzoni Aix-Marseille University
Frédéric Calon
Frédéric Calon Université Laval
Etienne Coutureau
Etienne Coutureau Centre national de la recherche scientifique, CNRS
Marie-Ève Tremblay
Marie-Ève Tremblay University of Victoria
Martine Cador
Martine Cador University of Bordeaux
Amanda Sierra
Amanda Sierra University of the Basque Country
Yves Desjardins
Yves Desjardins Université Laval

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