World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
108
Citations
47563
World Ranking
5958
National Ranking
3186

Research.com Recognitions

  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Keith W. Kelley is affiliated with the University of Illinois at Urbana-Champaign in the United States. Their research spans several interconnected fields primarily focused on neuroscience and medicine, with significant contributions to behavioral neuroscience, biological psychiatry, psychiatry and mental health, immunology, and molecular biology.

Their work frequently appears in scientific venues such as Brain Behavior and Immunity Integrative, Brain Behavior and Immunity, Brain Behavior & Immunity - Health, Annals of Allergy Asthma & Immunology, and Cell Metabolism. These publications highlight their focus on the interface between psychological processes and immune function.

Recent published papers by or associated with Keith W. Kelley include:

  • The Legacy of Sickness Behaviors, 2020, Frontiers in Psychiatry
  • Cancer and stress: NextGen strategies, 2020, Brain Behavior and Immunity
  • Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis, 2024, Cell Metabolism
  • Pyrroline-5-carboxylate reductase 1 reprograms proline metabolism to drive breast cancer stemness under psychological stress, 2023, Cell Death and Disease
  • Association of Persistent Symptoms after Lyme Neuroborreliosis and Increased Levels of Interferon-α in Blood, 2023, Emerging Infectious Diseases

Frequent collaborators include Quentin Liu, Jinxin Lü, Huandong Luo, Keyu Su, and Bai Cui. Strong research partnerships often accompany their studies, contributing to advancing knowledge in stress response, immune function, and psychiatric illness.

Their research themes include:

  • Stress Responses and Cortisol
  • Tryptophan and brain disorders
  • Cancer, Stress, Anesthesia, and Immune Response
  • Immune Cell Function and Interaction
  • Histone Deacetylase Inhibitors Research
  • Sirtuins and Resveratrol in Medicine
  • Optimism, Hope, and Well-being

Keith W. Kelley has authored or contributed to academic books, including the Textbook of Immunopsychiatry published by Cambridge University Press in 2021.

In 2011, they were recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • From inflammation to sickness and depression: when the immune system subjugates the brain

    Robert Dantzer;Jason C. O'Connor;Gregory G. Freund;Rodney W. Johnson

  • Twenty years of research on cytokine-induced sickness behavior

    Robert Dantzer;Keith W. Kelley

  • Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

    Jason O'Connor;M. A. Lawson;C. André;M. Moreau

  • Sickness behavior as a new target for drug development

    Stephen Kent;Rose Marie Bluthé;Keith W. Kelley;Robert Dantzer

  • Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system

    J. P. Godbout;J. Chen;J. Abraham;A. F. Richwine

  • Cytokine-induced sickness behavior

    Keith W. Kelley;Rose Marie Bluthé;Robert Dantzer;Jian Hua Zhou

  • Inflammation-associated depression: From serotonin to kynurenine

    Robert Dantzer;Jason C. O’Connor;Marcus A. Lawson;Keith W. Kelley

  • Stress and immunity: an integrated view of relationships between the brain and the immune system.

    Robert Dantzer;Keith W. Kelley

  • CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-α: relationship to CNS immune responses and depression

    Charles L. Raison;Robert Dantzer;Keith W. Kelley;Marcus A. Lawson

  • Interferon-γ and Tumor Necrosis Factor-α Mediate the Upregulation of Indoleamine 2,3-Dioxygenase and the Induction of Depressive-Like Behavior in Mice in Response to Bacillus Calmette-Guérin

    Jason C. O'Connor;Caroline André;Yunxia Wang;Marcus A. Lawson

  • Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior

    François Frenois;Maïté Moreau;Jason O’Connor;Marc Lawson

  • Interleukin-10 in the brain.

    Klemen Strle;Jian Hua Zhou;Wen Hong Shen;Suzanne R. Broussard

  • Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent?

    Robert Dantzer;Jan Pieter Konsman;Rose Marie Bluthé;Keith W. Kelley

  • Immune–neural connections: how the immune system’s response to infectious agents influences behavior

    Robert H. McCusker;Keith W. Kelley

  • Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1

    Saebyeol Jang;Keith W. Kelley;Rodney W. Johnson

  • NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice

    Adam K Walker;David P Budac;Stephanie Bisulco;Anna W Lee

  • Stress and immune function: a bibliographic review.

    K W Kelley

  • Lipopolysaccharide induces sickness behaviour in rats by a vagal mediated mechanism.

    R. M. Bluthe;V. Walter;P. Parnet;S. Laye

  • Subdiaphragmatic vagotomy blocks induction of IL-1 beta mRNA in mice brain in response to peripheral LPS.

    S. Laye;R. M. Bluthe;S. Kent;C. Combe

  • Effects of interleukin-1 receptor antagonist on the behavioral effects of lipopolysaccharide in rat.

    Rose Marie Bluthé;Robert Dantzer;Keith W. Kelley

Frequent Co-Authors

Robert Dantzer
Robert Dantzer The University of Texas MD Anderson Cancer Center
Rodney W. Johnson
Rodney W. Johnson University of Illinois at Urbana-Champaign
Nathalie Castanon
Nathalie Castanon University of Bordeaux
Sophie Layé
Sophie Layé University of Bordeaux
Justin S. Rhodes
Justin S. Rhodes University of Illinois at Urbana-Champaign
Annemieke Kavelaars
Annemieke Kavelaars The University of Texas MD Anderson Cancer Center
Sandra L. Rodriguez-Zas
Sandra L. Rodriguez-Zas University of Illinois at Urbana-Champaign
Stanley E. Curtis
Stanley E. Curtis University of Illinois at Urbana-Champaign
Cobi Jacoba Johanna Heijnen
Cobi Jacoba Johanna Heijnen The University of Texas MD Anderson Cancer Center
Jonathan P. Godbout
Jonathan P. Godbout The Ohio State University

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