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Neuroscience
Italy
2026

D-Index & Metrics

Neuroscience

D-Index
112
Citations
39180
World Ranking
513
National Ranking
11

Medicine

D-Index
112
Citations
39214
World Ranking
5197
National Ranking
164

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Italy Leader Award

Overview

Diego Centonze is affiliated with the University of Rome Tor Vergata in Italy, focusing on research primarily within the field of Medicine. Their work encompasses several subfields including Pathology and Forensic Medicine, Neurology, Molecular Biology, Oncology, and Immunology.

Their research output prominently includes studies on multiple sclerosis, with other notable areas of investigation covering polyomavirus and related diseases, peripheral neuropathies, neuroinflammation, neurodegeneration mechanisms, SARS-CoV-2 and COVID-19, systemic lupus erythematosus, and sleep and wakefulness research.

Notable recent publications by Diego Centonze include:

  • Myasthenia Gravis Associated With SARS-CoV-2 Infection, 2020, Annals of Internal Medicine
  • Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease, 2022, JAMA Neurology
  • Early use of high-efficacy disease-modifying therapies makes the difference in people with multiple sclerosis: an expert opinion, 2022, Journal of Neurology
  • COVID-19 in Patients with Multiple Sclerosis: Associations with Disease-Modifying Therapies, 2021, CNS Drugs
  • Comparison of switching to 6-week dosing of natalizumab versus continuing with 4-week dosing in patients with relapsing-remitting multiple sclerosis (NOVA): a randomised, controlled, open-label, phase 3b trial, 2022, The Lancet Neurology

Diego Centonze frequently collaborates with several co-authors, including:

  • Fabio Buttari
  • Mario Stampanoni Bassi
  • Ettore Dolcetti
  • Antonio Bruno
  • Luana Gilio

Their work is regularly published in a variety of academic venues, with frequent appearances in:

  • Frontiers in Neurology
  • Journal of Neurology
  • Multiple Sclerosis and Related Disorders
  • Multiple Sclerosis Journal
  • Therapeutic Advances in Neurological Disorders

Best Publications

  • Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression

    Giovanna Borsellino;Markus Kleinewietfeld;Diletta Di Mitri;Alexander Sternjak

  • Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

    Unknown

  • Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia

    Barbara Picconi;Diego Centonze;Kerstin Håkansson;Giorgio Bernardi

  • Acetylcholine-mediated modulation of striatal function.

    Paolo Calabresi;Diego Centonze;Paolo Gubellini;Antonio Pisani

  • Dopaminergic control of synaptic plasticity in the dorsal striatum

    Diego Centonze;Barbara Picconi;Paolo Gubellini;Giorgio Bernardi

  • Dopamine and cAMP-Regulated Phosphoprotein 32 kDa Controls Both Striatal Long-Term Depression and Long-Term Potentiation, Opposing Forms of Synaptic Plasticity

    Paolo Calabresi;Paolo Gubellini;Diego Centonze;Barbara Picconi

  • Inflammation Triggers Synaptic Alteration and Degeneration in Experimental Autoimmune Encephalomyelitis

    Diego Centonze;Luca Muzio;Silvia Rossi;Francesca Cavasinni

  • Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission.

    Paolo Gubellini;Barbara Picconi;Monica Bari;Natalia Battista

  • Abnormal Synaptic Plasticity in the Striatum of Mice Lacking Dopamine D2 Receptors

    Paolo Calabresi;Adolfo Saiardi;Antonio Pisani;Ja Hyun Baik

  • Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons

    A Pisani;P Gubellini;P Bonsi;F Conquet

  • Synaptic transmission in the striatum: from plasticity to neurodegeneration.

    P Calabresi;D Centonze;P Gubellini;G A Marfia

  • Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum

    Mauro Maccarrone;Silvia Rossi;Monica Bari;Valentina De Chiara

  • Distinct Roles of D1 and D5 Dopamine Receptors in Motor Activity and Striatal Synaptic Plasticity

    Diego Centonze;Cristina Grande;Emilia Saulle;Ana B. Martín

  • Effects of Anodal Transcranial Direct Current Stimulation on Chronic Neuropathic Pain in Patients With Multiple Sclerosis

    Francesco Mori;Claudia Codecà;Hajime Kusayanagi;Fabrizia Monteleone

  • Synaptopathy connects inflammation and neurodegeneration in multiple sclerosis

    Georgia Mandolesi;Antonietta Gentile;Alessandra Musella;Diego Fresegna

  • Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease.

    Giuseppe Filomeni;Ilaria Graziani;Daniela De Zio;Luciana Dini

  • Receptor Subtypes Involved in the Presynaptic and Postsynaptic Actions of Dopamine on Striatal Interneurons

    Diego Centonze;Cristina Grande;Alessandro Usiello;Paolo Gubellini

  • A Critical Role of the Nitric Oxide/cGMP Pathway in Corticostriatal Long-Term Depression

    Paolo Calabresi;Paolo Gubellini;Diego Centonze;Giuseppe Sancesario

  • Unilateral Dopamine Denervation Blocks Corticostriatal LTP

    Diego Centonze;Paolo Gubellini;Barbara Picconi;Paolo Calabresi

  • Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones

    Antonio Pisani;Paolo Calabresi;Diego Centonze;Giorgio Bernardi

  • The endocannabinoid system in targeting inflammatory neurodegenerative diseases

    Diego Centonze;Alessandro Finazzi-Agrò;Giorgio Bernardi;Mauro Maccarrone

  • The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis.

    Diego Centonze;Monica Bari;Silvia Rossi;Chiara Prosperetti

Frequent Co-Authors

Giorgio Bernardi
Giorgio Bernardi University of Rome Tor Vergata
Paolo Calabresi
Paolo Calabresi Catholic University of the Sacred Heart
Alessandra Musella
Alessandra Musella Università Telematica San Raffaele Roma
Silvia Rossi
Silvia Rossi Chiesi (Italy)
Antonio Pisani
Antonio Pisani University of Pavia
Mauro Maccarrone
Mauro Maccarrone University of L'Aquila
Paolo Gubellini
Paolo Gubellini Aix-Marseille University
Caterina Motta
Caterina Motta University of Rome Tor Vergata
Gianvito Martino
Gianvito Martino Vita-Salute San Raffaele University
Barbara Picconi
Barbara Picconi University of Rome Tor Vergata

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