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Jan Ceuppens

Jan Ceuppens

D-Index & Metrics

Immunology

D-Index
84
Citations
22424
World Ranking
1397
National Ranking
16

Medicine

D-Index
84
Citations
22515
World Ranking
15244
National Ranking
194

Overview

Jan Ceuppens is affiliated with KU Leuven in Belgium and has contributed extensively to the fields of Medicine, Immunology, and Microbiology. Their research primarily focuses on Immunology, Surgery, and Physiology, with additional work intersecting Food Science and Molecular Biology.

The scientist's research topics cover a range of immunological and microbiological themes. Key topics include:

  • IL-33, ST2, and ILC Pathways
  • Eosinophilic Esophagitis
  • Asthma and respiratory diseases
  • Immune Cell Function and Interaction
  • Probiotics and Fermented Foods
  • Gut microbiota and health
  • Immune Response and Inflammation

Jan Ceuppens has published in multiple scientific venues, frequently contributing to Frontiers in Immunology, where three publications are recorded. Other notable publication venues include the Journal of Crohn's and Colitis, Gut Microbes, Immunity Inflammation and Disease, and The Journal of Immunology.

Selected recent papers illustrate their research focus and include the following:

  • Lactobacillus rhamnosus probiotic prevents airway function deterioration and promotes gut microbiome resilience in a murine asthma model (2020, Gut Microbes)
  • Biological Therapy in Inflammatory Bowel Disease Patients Partly Restores Intestinal Innate Lymphoid Cell Subtype Equilibrium (2020, Frontiers in Immunology)
  • Innate Lymphoid Cells Are Required to Induce Airway Hyperreactivity in a Murine Neutrophilic Asthma Model (2022, Frontiers in Immunology)
  • Fibrogenesis in chronic murine colitis is independent of innate lymphoid cells (2020, Immunity Inflammation and Disease)
  • Peribronchial Inflammation Resulting from Regulatory T Cell Deficiency Damages the Respiratory Epithelium and Disturbs Barrier Function (2022, The Journal of Immunology)

Throughout their career, Jan Ceuppens has collaborated closely with several researchers. Frequent co-authors include Christine Breynaert, Jonathan Cremer, Sven Seys, Jeroen Vanoirbeek, and Brecht Creyns.

Best Publications

  • Regulation of the immune response by prostaglandins

    James S. Goodwin;Jan Ceuppens

  • IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?

    Dominique M A Bullens;Els Truyen;Liesbeth Coteur;Ellen Dilissen

  • Sub-Lingual Immunotherapy: World Allergy Organization Position Paper 2009

    G Walter Canonica;Jean Bousquet;Thomas Casale;Richard F Lockey

  • Sub-lingual immunotherapy: World Allergy Organization Position Paper 2009.

    Canonica Gw;Bousquet J;Casale T;Lockey Rf

  • Interleukin-17 Orchestrates the Granulocyte Influx into Airways after Allergen Inhalation in a Mouse Model of Allergic Asthma

    Peter W. Hellings;Ahmad Kasran;Zhanju Liu;Philippe Vandekerckhove

  • Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease

    Peter Suenaert;Veerle Bulteel;Liesbeth Lemmens;Maja Noman

  • CD80, CD86 and CD40 provide accessory signals in a multiple-step T-cell activation model.

    Stefaan W. Van Gool;Peter Vandenberghe;Mark de Boer;Jan L. Ceuppens

  • Impaired barrier function in patients with house dust mite-induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression.

    Brecht Steelant;Ricard Farré;Paulina Wawrzyniak;Jochen Belmans

  • Adalimumab induces apoptosis of human monocytes: a comparative study with infliximab and etanercept.

    Chong Shen;G Assche;Steven Colpaert;P Maerten

  • Infliximab induces potent anti-inflammatory and local immunomodulatory activity but no systemic immune suppression in patients with Crohn's disease.

    F. Cornillie;D. Shealy;G. D'Haens;K. Geboes

  • IL-15 is highly expressed in inflammatory bowel disease and regulates local T cell-dependent cytokine production.

    Zhanju Liu;Karel Geboes;Stefaan Colpaert;Geert R. D’Haens

  • Evaluation of airway inflammation by quantitative Th1/Th2 cytokine mRNA measurement in sputum of asthma patients

    Els Truyen;Liesbeth Coteur;Ellen Dilissen;Lut Overbergh

  • Flow cytometric measurement of cytoplasmic free calcium in human peripheral blood T lymphocytes with fluo-3, a new fluorescent calcium indicator.

    Peter A. Vandenberghe;Jan L. Ceuppens

  • Human T cell activation with phytohemagglutinin. The function of IL-6 as an accessory signal.

    J L Ceuppens;M L Baroja;K Lorre;J Van Damme

  • Haptoglobin directly affects T cells and suppresses T helper cell type 2 cytokine release

    M. Arredouani;P. Matthijs;E. Van Hoeyveld;A. Kasran

  • Histamine and T helper cytokine–driven epithelial barrier dysfunction in allergic rhinitis

    Brecht Steelant;Sven S.F. Seys;Laura Van Gerven;Matthias Van Woensel

  • Ligation of B7 with CD28/CTLA-4 on T cells results in CD40 ligand expression, interleukin-4 secretion and efficient help for antibody production by B cells.

    Mark de Boer;Ahmad Kasran;Jaap Kwekkeboom;Hugo Walter

  • Immune dysfunction in patients with functional gastrointestinal disorders

    S. Kindt;L. Van Oudenhove;D. Broekaert;A. Kasran

  • Measurement of serum cytokine levels in patients with myelodysplastic syndromes.

    G. E. G. Verhoef;P. De Schouwer;J. L. Ceuppens;J. Van Damme

  • Hyperexpression of CD40 Ligand (CD154) in Inflammatory Bowel Disease and Its Contribution to Pathogenic Cytokine Production

    Z Liu;Stefaan Colpaert;G R D'Haens;Ahmad Kasran

  • Identification of haptoglobin as an alternative ligand for CD11b/CD18.

    S. M. El Ghmati;E. M. Van Hoeyveld;J. A. G. Van Strijp;J. L. Ceuppens

Frequent Co-Authors

Sven Seys
Sven Seys KU Leuven
Louis Boon
Louis Boon University of Amsterdam
Lieven Dupont
Lieven Dupont KU Leuven
Karel Geboes
Karel Geboes Ghent University Hospital
Sarah Lebeer
Sarah Lebeer University of Antwerp

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