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Immunology

D-Index
94
Citations
29293
World Ranking
937
National Ranking
35

Medicine

D-Index
94
Citations
29399
World Ranking
10561
National Ranking
418

Overview

Louis Boon is affiliated with the University of Amsterdam in the Netherlands. Their research primarily focuses on immunology, microbiology, and medicine, with a particular emphasis on subfields including immunology, oncology, molecular biology, infectious diseases, and neurology.

The main topics of Boon's work include:

  • Immune Cell Function and Interaction
  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • Immunotherapy and Immune Responses
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • IL-33, ST2, and ILC Pathways

Boon has authored numerous papers with prominent venues including bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, SSRN Electronic Journal, Journal for ImmunoTherapy of Cancer, and Cell Reports. The paper publication counts show a significant presence especially in bioRxiv and Frontiers in Immunology.

Some of their recent published works include:

  • The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes (2020, Cancer Cell)
  • Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells (2020, Immunity)
  • Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy (2021, Journal for ImmunoTherapy of Cancer)
  • Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication (2022, Immunity)
  • IL1β Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D (2020, Cancer Immunology Research)

Boon frequently collaborates with other researchers in their field. Regular co-authors include:

  • Judith E. Allen
  • Isaure Vanmeerbeek
  • Abhishek D. Garg
  • Niels Vandamme
  • Bart N. Lambrecht

The research work of Louis Boon revolves significantly around cancer immunotherapy and immune system mechanisms, especially focusing on the regulation and function of various immune cell types, immune checkpoints, and inflammatory pathways. Their studies contribute to understanding both the immune responses in cancer and autoimmune conditions, often intersecting with therapeutic strategies.

Best Publications

  • Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis

    Leslie van der Fits;Sabine Mourits;Jane S. A. Voerman;Marius Kant

  • Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

    Maria T Pallotta;Ciriana Orabona;Claudia Volpi;Carmine Vacca

  • Aryl hydrocarbon receptor control of a disease tolerance defence pathway

    Alban Bessede;Alban Bessede;Marco Gargaro;Maria T. Pallotta;Davide Matino

  • The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes

    Floris Dammeijer;Mandy van Gulijk;Evalyn E. Mulder;Melanie Lukkes

  • Transfer of Central Nervous System Autoantigens and Presentation in Secondary Lymphoid Organs

    Alex F. de Vos;Marjan van Meurs;Herbert P. Brok;Leonie A. Boven

  • Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy.

    Ursula Grohmann;Claudia Volpi;Francesca Fallarino;Silvia Bozza

  • Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis

    Dirk Lievens;Dirk Lievens;Alma Zernecke;Tom Seijkens;Oliver Soehnlein

  • Infection with a helminth parasite attenuates autoimmunity through TGF-β-mediated suppression of Th17 and Th1 responses.

    Kevin P. Walsh;Miriam T. Brady;Conor M. Finlay;Louis Boon

  • Gaucher cells demonstrate a distinct macrophage phenotype and resemble alternatively activated macrophages.

    Leonie A. Boven;Marjan van Meurs;Rolf G. Boot;Atul Mehta

  • Dendritic cell vaccines based on immunogenic cell death elicit danger signals and T cell–driven rejection of high-grade glioma

    Abhishek D. Garg;Lien Vandenberk;Carolien Koks;Tina Verschuere

  • CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice

    Christian Weber;Svenja Meiler;Yvonne Döring;Miriam Koch

  • A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

    Mourad Matmati;Peggy Jacques;Jonathan Maelfait;Jonathan Maelfait;Eveline Verheugen

  • CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo.

    Oliver M. Grauer;Stefan Nierkens;Erik Bennink;Liza W.J. Toonen

  • Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

    Esther Lutgens;Esther Lutgens;Dirk Lievens;Dirk Lievens;Linda Beckers;Erwin Wijnands

  • The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity.

    Damya Laoui;Jiri Keirsse;Yannick Morias;Eva Van Overmeire

  • Sialic acid blockade suppresses tumor growth by enhancing T cell-mediated tumor immunity

    Christian Büll;Thomas J Boltje;Natasja Balneger;Sarah M Weischer

  • Newcastle disease virotherapy induces long-term survival and tumor-specific immune memory in orthotopic glioma through the induction of immunogenic cell death.

    Carolien A. Koks;Abhishek D. Garg;Michael Ehrhardt;Matteo Riva

  • Natural killer T cells in adipose tissue prevent insulin resistance

    Henk S Schipper;Maryam Rakhshandehroo;Stan F J van de Graaf;Koen Venken

  • Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells That Promote Pathogenic T Cells

    Aoife M. McGinley;Caroline E. Sutton;Sarah C. Edwards;Charlotte M. Leane

  • Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation

    Natalia B. Pikor;Jillian L. Astarita;Jillian L. Astarita;Leslie Summers-Deluca;Georgina Galicia

  • An Anti-Inflammatory Role for Plasmacytoid Dendritic Cells in Allergic Airway Inflammation

    Mirjam Kool;Menno van Nimwegen;Monique A. M. Willart;Femke Muskens

  • Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells

    Ronald Backer;Timo Schwandt;Mascha Greuter;Marije Oosting

Frequent Co-Authors

Bart N. Lambrecht
Bart N. Lambrecht Ghent University
Jan Ceuppens
Jan Ceuppens KU Leuven
Esther Lutgens
Esther Lutgens Ludwig-Maximilians-Universität München
Christian Weber
Christian Weber Ludwig-Maximilians-Universität München
Johan Garssen
Johan Garssen Utrecht University
Erik A.L. Biessen
Erik A.L. Biessen Maastricht University
Raymond Pieters
Raymond Pieters Utrecht University
Jon D. Laman
Jon D. Laman University Medical Center Groningen
Marion J.J. Gijbels
Marion J.J. Gijbels Maastricht University
Paolo Puccetti
Paolo Puccetti University of Perugia

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Related Online Degrees & Career Pathways

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Career salaries can vary widely depending on specialization and location. Referencing data on DNP salary by specialty offers insight on financial prospects in advanced immunology-related nursing roles across different states.

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