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Marion J.J. Gijbels

Marion J.J. Gijbels

D-Index & Metrics

Molecular Biology

D-Index
55
Citations
12077
World Ranking
2267
National Ranking
52

Overview

Marion J.J. Gijbels is affiliated with Maastricht University in the Netherlands and has a research focus primarily situated in medicine, biochemistry, genetics, and molecular biology, as well as immunology and microbiology. Their body of work spans multiple interconnected fields and subfields of study, with notable emphasis on immunology, molecular biology, surgery, epidemiology, and cancer research.

The scientific output of Marion J.J. Gijbels includes numerous publications in prominent journals, reflecting engagement with both fundamental and applied biomedical research. Some recent papers include:

  • Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques, 2020, Nature Communications
  • Integrative multiomics analysis of human atherosclerosis reveals a serum response factor-driven network associated with intraplaque hemorrhage, 2021, Clinical and Translational Medicine
  • CARMN Loss Regulates Smooth Muscle Cells and Accelerates Atherosclerosis in Mice, 2021, Circulation Research
  • Protective role of chaperone-mediated autophagy against atherosclerosis, 2022, Proceedings of the National Academy of Sciences
  • Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2, 2021, EMBO Reports

Marion's research often investigates cardiovascular disease mechanisms, particularly atherosclerosis, and the immune system's role in disease development and progression. The main topics covered in their work include:

  • Atherosclerosis and cardiovascular diseases
  • Immune cells in cancer
  • Liver disease diagnosis and treatment
  • Cancer, hypoxia, and metabolism
  • Cholesterol and lipid metabolism
  • Circular RNAs in diseases
  • Single-cell and spatial transcriptomics

The publishing venues where Marion J.J. Gijbels frequently disseminates research findings include:

  • Frontiers in Immunology
  • Atherosclerosis
  • Cardiovascular Research
  • Clinical and Translational Medicine
  • Frontiers in Cardiovascular Medicine

Frequent co-authors collaborating with Marion include:

  • Erik A.L. Biessen
  • Judith C. Sluimer
  • Kim van Kuijk
  • Menno P.J. de Winther
  • Barend Mees

Their research integrates multiple specialized domains, combining molecular and cellular biology approaches with clinical insights to address complex diseases, especially atherosclerosis and cancer. The work demonstrates involvement in exploring cellular metabolism, immune responses, and disease pathophysiology, contributing to the understanding of cardiovascular and oncological disorders.

Best Publications

  • Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo

    Nadine Jetten;Sanne Verbruggen;Marion J. Gijbels;Mark J. Post

  • Distribution of macrophage polarization markers in human atherosclerosis

    J. Lauran Stöger;Marion J.J. Gijbels;Marion J.J. Gijbels;Saskia van der Velden;Marco Manca

  • Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis.

    Ralph Gareus;Elena Kotsaki;Sofia Xanthoulea;Ingeborg van der Made

  • Transforming growth factor-beta mediates balance between inflammation and fibrosis during plaque progression.

    Esther Lutgens;Marion Gijbels;Marjan Smook;Peter Heeringa

  • Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice.

    B. J. M. Van Vlijmen;A. M. J. M. Van Den Maagdenberg;M. J. J. Gijbels;H. Van Der Boom

  • Myeloid Type I Interferon Signaling Promotes Atherosclerosis by Stimulating Macrophage Recruitment to Lesions

    Pieter Goossens;Marion J.J. Gijbels;Alma Zernecke;Wouter Eijgelaar

  • Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR−/− Mice

    Marcella van Leeuwen;Marion J. J. Gijbels;Adriaan Duijvestijn;Marjan Smook

  • Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis

    Tom T.P. Seijkens;Claudia M. van Tiel;Pascal J.H. Kusters;Dorothee Atzler

  • Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis

    Anouk A.J. Hamers;Mariska Vos;Fadi Rassam;Goran Marinković

  • Hematopoietic miR155 Deficiency Enhances Atherosclerosis and Decreases Plaque Stability in Hyperlipidemic Mice

    Marjo M. P. C. Donners;Ine M. J. Wolfs;Lauran J. Stöger;Emiel P. C. van der Vorst

  • Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

    Antonios Chatzigeorgiou;Tom Seijkens;Barbara Zarzycka;David Engel

  • Polycyclic aromatic hydrocarbons induce an inflammatory atherosclerotic plaque phenotype irrespective of their DNA binding properties.

    Daniëlle M.J. Curfs;Ad M. Knaapen;Daniëlle M.F.A. Pachen;Marion J.J. Gijbels

  • Internalization of Modified Lipids by CD36 and SR-A Leads to Hepatic Inflammation and Lysosomal Cholesterol Storage in Kupffer Cells

    Veerle Bieghs;Fons Verheyen;Patrick J. van Gorp;Tim Hendrikx

  • Post-natal myogenic and adipogenic developmental: defects and metabolic impairment upon loss of A-type lamins.

    Nard Kubben;Jan Willem Voncken;Gonda Konings;Michel van Weeghel

  • Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition.

    Stijn A.I. Ghesquiere;Marion J.J. Gijbels;Marit Anthonsen;Patrick J.J. van Gorp

  • High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

    Emiel P.C. van der Vorst;Emiel P.C. van der Vorst;Kosta Theodorou;Yongzheng Wu;Marten A. Hoeksema

  • Macrophage-specific inhibition of NF-κB activation reduces foam-cell formation

    Valérie Ferreira;Ko Willems van Dijk;Albert K. Groen;Rogier M. Vos

  • Chronic Exposure to the Carcinogenic Compound Benzo[a]Pyrene Induces Larger and Phenotypically Different Atherosclerotic Plaques in ApoE-Knockout Mice

    Daniëlle M.J. Curfs;Esther Lutgens;Marion J.J. Gijbels;Mark M. Kockx

  • Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology.

    Danielle M. J. Curfs;Stijn A. I. Ghesquiere;Monique N. Vergouwe;Ingeborg van der Made

  • Celecoxib-loaded PEA microspheres as an auto regulatory drug-delivery system after intra-articular injection

    Unknown

Frequent Co-Authors

Menno P.J. de Winther
Menno P.J. de Winther University of Amsterdam
Erik A.L. Biessen
Erik A.L. Biessen Maastricht University
Marten H. Hofker
Marten H. Hofker University Medical Center Groningen
Esther Lutgens
Esther Lutgens Ludwig-Maximilians-Universität München
Christian Weber
Christian Weber Ludwig-Maximilians-Universität München
Mat J.A.P. Daemen
Mat J.A.P. Daemen University of Amsterdam
Christoph J. Binder
Christoph J. Binder Medical University of Vienna
Dieter Lütjohann
Dieter Lütjohann University Hospital Bonn
Louis M. Havekes
Louis M. Havekes Leiden University Medical Center

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