The scientist’s investigation covers issues in Cholesterol, Internal medicine, Endocrinology, Alzheimer's disease and Apolipoprotein E. His work is dedicated to discovering how Cholesterol, Vascular dementia are connected with Neurodegeneration and other disciplines. Dementia, Central nervous system, Campesterol, Simvastatin and Amyloid precursor protein are the core of his Internal medicine study.
His Endocrinology research includes elements of ABCG5, Cerebrospinal fluid and ABCG8. The Alzheimer's disease study combines topics in areas such as Central nervous system disease, Degenerative disease, Hydroxymethylglutaryl-CoA reductase, Blood plasma and Single-nucleotide polymorphism. The various areas that he examines in his Apolipoprotein E study include Genetic variation, Lipoprotein, Low-density lipoprotein and Lovastatin.
His primary areas of investigation include Internal medicine, Endocrinology, Cholesterol, Lathosterol and Sterol. His research brings together the fields of Gastroenterology and Internal medicine. Dieter Lütjohann has included themes like Alzheimer's disease, Inflammation and Cerebrospinal fluid in his Endocrinology study.
Cholesterol is a primary field of his research addressed under Biochemistry. His Lathosterol study integrates concerns from other disciplines, such as Placebo and Lanosterol. His Sterol research focuses on ABCG5 and how it connects with ABCG8.
Dieter Lütjohann mainly focuses on Internal medicine, Cholesterol, Endocrinology, Campesterol and Lathosterol. Dieter Lütjohann combines subjects such as Gastroenterology and Cardiology with his study of Internal medicine. His Cholesterol research is multidisciplinary, incorporating elements of Steatohepatitis and In vivo.
In his study, Low-density lipoprotein is inextricably linked to Inflammation, which falls within the broad field of Endocrinology. His study looks at the intersection of Lathosterol and topics like Placebo with Chitosan and Plant sterols. His Ezetimibe research is multidisciplinary, relying on both Simvastatin and Pharmacology.
His primary scientific interests are in Internal medicine, Cholesterol, Endocrinology, Cell biology and Campesterol. Internal medicine is closely attributed to Brain Structure and Function in his study. His Cholesterol study focuses on Reverse cholesterol transport in particular.
His Cell biology research incorporates elements of Transcription factor, Sterol regulatory element-binding protein, Sterol and Niemann–Pick disease, type C. His Sterol study incorporates themes from Sphingosine, LDL receptor, Sphingolipid, Lyase and Downregulation and upregulation. Many of his research projects under Biochemistry are closely connected to Edible seaweed with Edible seaweed, tying the diverse disciplines of science together.
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Beneficial Effects of High Dietary Fiber Intake in Patients with Type 2 Diabetes Mellitus
Manisha Chandalia;Abhimanyu Garg;D. Lutjohann;K. von Bergmann.
The New England Journal of Medicine (2000)
Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo
K. Fassbender;M. Simons;C. Bergmann;M. Stroick.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
Liqing Yu;Robert E. Hammer;Jia Li-Hawkins;Klaus von Bergmann.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation
Dieter Lutjohann;Olof Breuer;Gunvor Ahlborg;Inger Nennesmo.
Proceedings of the National Academy of Sciences of the United States of America (1996)
Inhibition of Intestinal Cholesterol Absorption by Ezetimibe in Humans
Thomas Sudhop;Dieter Lütjohann;Annette Kodal;Michael Igel.
Circulation (2002)
Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation
Ingemar Björkhem;Dieter Lütjohann;Ulf Diczfalusy;Lars Ståhle.
Journal of Lipid Research (1998)
Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial.
Mikael Simons;Frank Schwärzler;Dieter Lütjohann;Klaus Von Bergmann.
Annals of Neurology (2002)
Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
Kristiaan Wouters;Patrick J. van Gorp;Veerle Bieghs;Marion J. Gijbels.
Hepatology (2008)
Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease
Helena Gylling;Jogchum Plat;Stephen Turley;Henry N. Ginsberg.
Atherosclerosis (2014)
Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients.
Dieter Lütjohann;Dieter Lütjohann;Andreas Papassotiropoulos;Ingemar Björkhem;Sandra Locatelli.
Journal of Lipid Research (2000)
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