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Molecular Biology

D-Index
70
Citations
32261
World Ranking
1394
National Ranking
707

Overview

Sheila A. Shurtleff is affiliated with St. Jude Children's Research Hospital in the United States. Their research primarily lies within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. The scientist's work spans several subfields including Molecular Biology, Neurology, Cancer Research, Genetics, and Pulmonary and Respiratory Medicine.

Their main research topics include Cancer Genomics and Diagnostics, Sarcoma Diagnosis and Treatment, Bone Tumor Diagnosis and Treatments, Neurofibromatosis and Schwannoma Cases, Glioma Diagnosis and Treatment, Epigenetics and DNA Methylation, as well as Biomedical and Engineering Education.

Recent publications by Sheila A. Shurtleff have appeared in various scientific venues such as Archives of Pathology & Laboratory Medicine, npj Precision Oncology, UNC Libraries, Journal of Molecular Diagnostics, and Cancer Research. Notable papers include:

  • Diagnostic Utility of a Custom 34-Gene Anchored Multiplex PCR-Based Next-Generation Sequencing Fusion Panel for the Diagnosis of Bone and Soft Tissue Neoplasms With Identification of Novel USP6 Fusion Partners in Aneurysmal Bone Cysts, 2020, Archives of Pathology & Laboratory Medicine
  • Deregulation of DUX4 and ERG in acute lymphoblastic leukemia, 2020, UNC Libraries
  • Comparison of DNA methylation based classification models for precision diagnostics of central nervous system tumors, 2024, npj Precision Oncology
  • A Model for Design and Implementation of a Laboratory Information-Management System Specific for Molecular Pathology Laboratory Operations, 2022, Journal of Molecular Diagnostics
  • Abstract 642: Genomes for Kids: Comprehensive DNA and RNA sequencing defining the scope of actionable mutations in pediatric cancer, 2021, Cancer Research

Frequent collaborators include Elizabeth M. Azzato, Josephine K. Dermawan, Zheng Jin Tu, Steven D. Billings, and Daniel H. Farkas, indicating a consistent engagement with research teams specializing in related biomedical and oncological fields.

Best Publications

  • Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling.

    Eng Juh Yeoh;Mary E. Ross;Sheila A. Shurtleff;W. Kent Williams

  • Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

    Charles G. Mullighan;Salil Goorha;Ina Radtke;Christopher B. Miller

  • The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

    Jinghui Zhang;Li Ding;Linda Holmfeldt;Gang Wu

  • Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.

    Charles G Mullighan;Xiaoping Su;Jinghui Zhang;Ina Radtke

  • D-type cyclin-dependent kinase activity in mammalian cells.

    H Matsushime;D E Quelle;S A Shurtleff;M Shibuya

  • Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts.

    D. E. Quelle;R. A. Ashmun;S. A. Shurtleff;Jun-Ya Kato

  • Germline Mutations in Predisposition Genes in Pediatric Cancer

    Jinghui Zhang;Michael F. Walsh;Gang Wu;Michael N. Edmonson

  • BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

    Charles G. Mullighan;Christopher B. Miller;Ina Radtke;Letha A. Phillips

  • Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia

    Charles G. Mullighan;Letha A. Phillips;Xiaoping Su;Jing Ma

  • Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report From the International Microarray Innovations in Leukemia Study Group

    Torsten Haferlach;Alexander Kohlmann;Lothar Wieczorek;Giuseppe Basso

  • Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

    Jinghui Zhang;Gang Wu;Claudia P. Miller;Ruth G. Tatevossian

  • The genomic landscape of hypodiploid acute lymphoblastic leukemia

    Linda Holmfeldt;Lei Wei;Ernesto Diaz-Flores;Michael Walsh

  • TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis.

    Shurtleff Sa;Buijs A;Behm Fg;Rubnitz Je

  • Classification of pediatric acute lymphoblastic leukemia by gene expression profiling

    Mary E. Ross;Xiaodong Zhou;Guangchun Song;Sheila A. Shurtleff

  • Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma

    Xiang Chen;Armita Bahrami;Alberto Pappo;John Easton

  • C11orf95 – RELA fusions drive oncogenic NF-κB signalling in ependymoma

    Matthew Parker;Kumarasamypet M. Mohankumar;Chandanamali Punchihewa;Ricardo Weinlich

  • A novel retinoblastoma therapy from genomic and epigenetic analyses

    Jinghui Zhang;Claudia A. Benavente;Justina McEvoy;Jacqueline Flores-Otero

  • Gene expression profiling of pediatric acute myelogenous leukemia.

    Mary E. Ross;Rami Mahfouz;Mihaela Onciu;Hsi Che Liu

  • Genomic Landscape of Ewing Sarcoma Defines an Aggressive Subtype with Co-Association of STAG2 and TP53 Mutations

    Franck Tirode;Didier Surdez;Xiaotu Ma;Matthew Parker

  • The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias.

    Anna K. Andersson;Anna K. Andersson;Jing Ma;Jianmin Wang;Xiang Chen

Frequent Co-Authors

James R. Downing
James R. Downing St. Jude Children's Research Hospital
Ching-Hon Pui
Ching-Hon Pui St. Jude Children's Research Hospital
Jinghui Zhang
Jinghui Zhang St. Jude Children's Research Hospital
Susana C. Raimondi
Susana C. Raimondi St. Jude Children's Research Hospital
John Easton
John Easton St. Jude Children's Research Hospital
Charles G. Mullighan
Charles G. Mullighan St. Jude Children's Research Hospital
Jeffrey E. Rubnitz
Jeffrey E. Rubnitz St. Jude Children's Research Hospital
Michael Rusch
Michael Rusch St. Jude Children's Research Hospital
Stanley Pounds
Stanley Pounds St. Jude Children's Research Hospital
Raul C. Ribeiro
Raul C. Ribeiro St. Jude Children's Research Hospital

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