D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 64 Citations 20,041 210 World Ranking 6143 National Ranking 2897

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Mutation

John Easton spends much of his time researching Cancer research, Mutation, Genetics, Cancer and ATRX. John Easton has included themes like Somatic cell, Leukemia, Immunology, Neuroblastoma RAS viral oncogene homolog and PI3K/AKT/mTOR pathway in his Cancer research study. The Mutation study combines topics in areas such as Gene rearrangement, Epigenetics and Transplantation.

His study in Genomics, Gene, Genome, Transcription factor and Exome sequencing is carried out as part of his Genetics studies. His research integrates issues of Retinoblastoma, Exome and Syk in his study of Cancer. His ATRX research integrates issues from Fusion gene and Glioma.

His most cited work include:

  • The genetic basis of early T-cell precursor acute lymphoblastic leukaemia (1109 citations)
  • Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia (737 citations)
  • The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma (592 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Cancer research, Genetics, Cancer, Gene and Mutation. His Cancer research research includes elements of Leukemia, PI3K/AKT/mTOR pathway, Somatic evolution in cancer and ATRX. His Leukemia study combines topics in areas such as Myeloid and Myeloid leukemia.

His work investigates the relationship between Cancer and topics such as Oncology that intersect with problems in Cohort and Germline mutation. His biological study deals with issues like Molecular biology, which deal with fields such as Gene isoform and Alternative splicing. His research is interdisciplinary, bridging the disciplines of Somatic cell and Mutation.

He most often published in these fields:

  • Cancer research (33.50%)
  • Genetics (24.50%)
  • Cancer (17.50%)

What were the highlights of his more recent work (between 2019-2021)?

  • Cancer research (33.50%)
  • Cancer (17.50%)
  • Computational biology (10.50%)

In recent papers he was focusing on the following fields of study:

John Easton mainly investigates Cancer research, Cancer, Computational biology, Internal medicine and Cohort. His study in Cancer research is interdisciplinary in nature, drawing from both Mutation, Gene, Leukemia and Immunotherapy. His Mutation research is multidisciplinary, incorporating elements of Gene duplication, Transcriptome and Clone.

John Easton works in the field of Cancer, focusing on Pediatric cancer in particular. John Easton interconnects RNA-Seq, Genome, DNA sequencing and Indel in the investigation of issues within Computational biology. His research investigates the connection with Internal medicine and areas like Oncology which intersect with concerns in Cancer treatment.

Between 2019 and 2021, his most popular works were:

  • Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia (49 citations)
  • Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs (28 citations)
  • MYCN amplification and ATRX mutations are incompatible in neuroblastoma. (22 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Mutation

John Easton mostly deals with Mutation, Cancer research, Internal medicine, Childhood cancer and Oncology. His research in Mutation intersects with topics in Clone and Genomics. In his works, John Easton undertakes multidisciplinary study on Cancer research and Increased drug tolerance.

His Internal medicine research is multidisciplinary, relying on both Neoplasm, Germline mutation and DNA repair. His studies in Childhood cancer integrate themes in fields like Biomarker, Cohort study, Thyroid cancer and Telomere. John Easton combines subjects such as Single-nucleotide polymorphism and Cohort with his study of Oncology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Jinghui Zhang;Li Ding;Linda Holmfeldt;Gang Wu.
Nature (2012)

1608 Citations

Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia

K. G. Roberts;Y. Li;D. Payne-Turner;R. C. Harvey.
The New England Journal of Medicine (2014)

1222 Citations

Germline Mutations in Predisposition Genes in Pediatric Cancer

Jinghui Zhang;Michael F. Walsh;Gang Wu;Michael N. Edmonson.
The New England Journal of Medicine (2015)

929 Citations

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

Gang Wu;Alexander K Diaz;Alexander K Diaz;Barbara S Paugh;Sherri L Rankin.
Nature Genetics (2014)

866 Citations

Novel mutations target distinct subgroups of medulloblastoma

Giles Robinson;Matthew Parker;Tanya A. Kranenburg;Charles Lu;Charles Lu.
Nature (2012)

794 Citations

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

Jinghui Zhang;Gang Wu;Claudia P. Miller;Ruth G. Tatevossian.
Nature Genetics (2013)

677 Citations

The genomic landscape of hypodiploid acute lymphoblastic leukemia

Linda Holmfeldt;Lei Wei;Ernesto Diaz-Flores;Michael Walsh.
Nature Genetics (2013)

670 Citations

mTOR and cancer therapy.

J B Easton;P J Houghton.
Oncogene (2006)

592 Citations

The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia

Yu Liu;John Easton;Ying Shao;Jamie Maciaszek.
Nature Genetics (2017)

587 Citations

C11orf95 – RELA fusions drive oncogenic NF-κB signalling in ependymoma

Matthew Parker;Kumarasamypet M. Mohankumar;Chandanamali Punchihewa;Ricardo Weinlich.
Nature (2014)

561 Citations

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