2019 - Distinguished Fellows of the American Association of Immunologists (AAI)
His primary scientific interests are in Cell biology, Signal transduction, Receptor, Molecular biology and B cell. His work carried out in the field of Cell biology brings together such families of science as T cell and Apoptosis. His Signal transduction research includes themes of breakpoint cluster region, B-cell receptor and Fc receptor.
His Receptor research is multidisciplinary, incorporating perspectives in Major histocompatibility complex, Antigen and Phosphorylation. His biological study spans a wide range of topics, including Cyclin-dependent kinase 2, Tyrosine phosphorylation, MHC class I, Receptor complex and Antigen presentation. His studies in B cell integrate themes in fields like CD5 and Cellular differentiation.
His primary areas of investigation include Cell biology, Signal transduction, Receptor, Immunology and B cell. His research in Cell biology intersects with topics in T cell and B-cell receptor. His study focuses on the intersection of Signal transduction and fields such as T-cell receptor with connections in the field of CD8.
He usually deals with Receptor and limits it to topics linked to Phosphorylation and Syk and Tyrosine. His study explores the link between B cell and topics such as Molecular biology that cross with problems in MHC class II and Cell. John C. Cambier has included themes like Antibody and Depolarization in his Antigen study.
Immunology, B cell, Cell biology, Signal transduction and Autoimmunity are his primary areas of study. As a part of the same scientific family, John C. Cambier mostly works in the field of B cell, focusing on Molecular biology and, on occasion, CD40, Cytotoxic T cell and T cell. The concepts of his Cell biology study are interwoven with issues in B-cell activation, Interferon, Apoptosis, Transmembrane protein and breakpoint cluster region.
His research in Signal transduction intersects with topics in Phosphatase and Cancer research. B-cell receptor is frequently linked to Receptor in his study. His Receptor research is multidisciplinary, incorporating elements of Tyrosine, Phosphorylation and T-cell receptor.
John C. Cambier mostly deals with Immunology, Signal transduction, Cell biology, B cell and Autoimmunity. His study connects Interferon and Signal transduction. The study incorporates disciplines such as microRNA, Cellular Reprogramming Techniques, Induced pluripotent stem cell, breakpoint cluster region and RNA transfection in addition to Cell biology.
Particularly relevant to B-cell receptor is his body of work in B cell. Protein tyrosine phosphatase is a subfield of Receptor that John C. Cambier studies. In the field of Receptor, his study on Tyrosine kinase overlaps with subjects such as Immunoglobulin Fc.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
B cell antigen receptor signaling 101.
Joseph M Dal Porto;Stephen B Gauld;Kevin T Merrell;David Mills.
Molecular Immunology (2004)
Antigen and Fc receptor signaling. The awesome power of the immunoreceptor tyrosine-based activation motif (ITAM).
J C Cambier.
Journal of Immunology (1995)
Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1.
Daniele D'Ambrosio;Keli L. Hippen;Keli L. Hippen;Stacey A. Minskoff;Ira Mellman.
Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit
CM Pleiman;WM Hertz;JC Cambier.
Signal Transduction by the B Cell Antigen Receptor and its Coreceptors
J C Cambier;C M Pleiman;M R Clark.
Annual Review of Immunology (1994)
Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production
Michael J. White;Michael J. White;Kate McArthur;Kate McArthur;Donald Metcalf;Donald Metcalf;Rachael M. Lane.
Ia binding ligands and cAMP stimulate nuclear translocation of PKC in B lymphocytes
Cambier Jc;Newell Mk;Justement Lb;McGuire Jc.
Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
Eric T. Clambey;Eóin N. McNamee;Joseph A. Westrich;Louise E. Glover.
Proceedings of the National Academy of Sciences of the United States of America (2012)
B-cell anergy: from transgenic models to naturally occurring anergic B cells?
John C. Cambier;Stephen B. Gauld;Kevin T. Merrell;Barbara J. Vilen.
Nature Reviews Immunology (2007)
Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases.
Lucia Olcese;Paul Lang;Frédéric Vély;Anna Cambiaggi;Anna Cambiaggi.
Journal of Immunology (1996)
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