H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 100 Citations 29,706 293 World Ranking 696 National Ranking 442

Research.com Recognitions

Awards & Achievements

2019 - Distinguished Fellows of the American Association of Immunologists (AAI)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Enzyme

His primary scientific interests are in Cell biology, Signal transduction, Receptor, Molecular biology and B cell. His work carried out in the field of Cell biology brings together such families of science as T cell and Apoptosis. His Signal transduction research includes themes of breakpoint cluster region, B-cell receptor and Fc receptor.

His Receptor research is multidisciplinary, incorporating perspectives in Major histocompatibility complex, Antigen and Phosphorylation. His biological study spans a wide range of topics, including Cyclin-dependent kinase 2, Tyrosine phosphorylation, MHC class I, Receptor complex and Antigen presentation. His studies in B cell integrate themes in fields like CD5 and Cellular differentiation.

His most cited work include:

  • Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1. (492 citations)
  • Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1. (492 citations)
  • B cell antigen receptor signaling 101. (424 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Cell biology, Signal transduction, Receptor, Immunology and B cell. His research in Cell biology intersects with topics in T cell and B-cell receptor. His study focuses on the intersection of Signal transduction and fields such as T-cell receptor with connections in the field of CD8.

He usually deals with Receptor and limits it to topics linked to Phosphorylation and Syk and Tyrosine. His study explores the link between B cell and topics such as Molecular biology that cross with problems in MHC class II and Cell. John C. Cambier has included themes like Antibody and Depolarization in his Antigen study.

He most often published in these fields:

  • Cell biology (42.57%)
  • Signal transduction (32.29%)
  • Receptor (30.00%)

What were the highlights of his more recent work (between 2011-2021)?

  • Immunology (29.14%)
  • B cell (28.57%)
  • Cell biology (42.57%)

In recent papers he was focusing on the following fields of study:

Immunology, B cell, Cell biology, Signal transduction and Autoimmunity are his primary areas of study. As a part of the same scientific family, John C. Cambier mostly works in the field of B cell, focusing on Molecular biology and, on occasion, CD40, Cytotoxic T cell and T cell. The concepts of his Cell biology study are interwoven with issues in B-cell activation, Interferon, Apoptosis, Transmembrane protein and breakpoint cluster region.

His research in Signal transduction intersects with topics in Phosphatase and Cancer research. B-cell receptor is frequently linked to Receptor in his study. His Receptor research is multidisciplinary, incorporating elements of Tyrosine, Phosphorylation and T-cell receptor.

Between 2011 and 2021, his most popular works were:

  • Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production (384 citations)
  • Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa (322 citations)
  • B Cell Receptor Signal Transduction in the GC Is Short-Circuited by High Phosphatase Activity (182 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Enzyme

John C. Cambier mostly deals with Immunology, Signal transduction, Cell biology, B cell and Autoimmunity. His study connects Interferon and Signal transduction. The study incorporates disciplines such as microRNA, Cellular Reprogramming Techniques, Induced pluripotent stem cell, breakpoint cluster region and RNA transfection in addition to Cell biology.

Particularly relevant to B-cell receptor is his body of work in B cell. Protein tyrosine phosphatase is a subfield of Receptor that John C. Cambier studies. In the field of Receptor, his study on Tyrosine kinase overlaps with subjects such as Immunoglobulin Fc.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

B cell antigen receptor signaling 101.

Joseph M Dal Porto;Stephen B Gauld;Kevin T Merrell;David Mills.
Molecular Immunology (2004)

668 Citations

Antigen and Fc receptor signaling. The awesome power of the immunoreceptor tyrosine-based activation motif (ITAM).

J C Cambier.
Journal of Immunology (1995)

656 Citations

Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1.

Daniele D'Ambrosio;Keli L. Hippen;Keli L. Hippen;Stacey A. Minskoff;Ira Mellman.
Science (1995)

624 Citations

Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit

CM Pleiman;WM Hertz;JC Cambier.
Science (1994)

612 Citations

Signal Transduction by the B Cell Antigen Receptor and its Coreceptors

J C Cambier;C M Pleiman;M R Clark.
Annual Review of Immunology (1994)

574 Citations

Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production

Michael J. White;Michael J. White;Kate McArthur;Kate McArthur;Donald Metcalf;Donald Metcalf;Rachael M. Lane.
Cell (2014)

453 Citations

Ia binding ligands and cAMP stimulate nuclear translocation of PKC in B lymphocytes

Cambier Jc;Newell Mk;Justement Lb;McGuire Jc.
Nature (1987)

434 Citations

Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

Eric T. Clambey;Eóin N. McNamee;Joseph A. Westrich;Louise E. Glover.
Proceedings of the National Academy of Sciences of the United States of America (2012)

414 Citations

B-cell anergy: from transgenic models to naturally occurring anergic B cells?

John C. Cambier;Stephen B. Gauld;Kevin T. Merrell;Barbara J. Vilen.
Nature Reviews Immunology (2007)

394 Citations

Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases.

Lucia Olcese;Paul Lang;Frédéric Vély;Anna Cambiaggi;Anna Cambiaggi.
Journal of Immunology (1996)

388 Citations

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