World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
80
Citations
27882
World Ranking
4025
National Ranking
1988

Overview

Kennan C. Marsh is affiliated with AbbVie in the United States and has contributed extensively to medical research, particularly in the fields of hematology, physiology, public health, environmental and occupational health, parasitology, and genetics.

The scientist's recent publications encompass a range of topics related to parasitic diseases, cancer therapeutics, and pharmacology. Key papers include:

  • Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned, 2020, International Journal for Parasitology
  • Pyrrolopyrimidine Bumped Kinase Inhibitors for the Treatment of Cryptosporidiosis, 2021, ACS Infectious Diseases
  • Expanding the Repertoire for "Large Small Molecules": Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers, 2021, Molecular Cancer Therapeutics
  • Navitoclax safety, tolerability, and effect on biomarkers of senescence and neurodegeneration in aged nonhuman primates, 2024, Heliyon
  • Metabolite profiling of foslevodopa/foscarbidopa in plasma of healthy human participants by LC-HRMS indicates no major differences compared to administration of levodopa/carbidopa intestinal gel, 2024, Pharmacology Research & Perspectives

The scientific output covers a majority focus on medicine, with 26 publications within this primary field. More specifically, research concentration lies in several subfields:

  • Hematology
  • Physiology
  • Public Health, Environmental and Occupational Health
  • Parasitology
  • Genetics

Marsh's work also addresses multiple topics across chronic and acute leukemias as well as parasitic infections and cellular biology, including:

  • Chronic Myeloid Leukemia Treatments
  • Telomeres, Telomerase, and Senescence
  • Parasitic Infections and Diagnostics
  • Chronic Lymphocytic Leukemia Research
  • Retinoids in leukemia and cellular processes
  • Acute Lymphoblastic Leukemia research
  • Acute Myeloid Leukemia Research

The scientist frequently collaborates with several researchers, as indicated by repeated coauthorships with:

  • Dale J. Kempf
  • Ryan Choi
  • Matthew A. Hulverson
  • Grant R. Whitman
  • Lynn K. Barrett

Marsh has published multiple times in venues notably including:

  • PLoS neglected tropical diseases
  • SSRN Electronic Journal
  • Heliyon
  • International Journal for Parasitology
  • ACS Infectious Diseases

Best Publications

  • ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

    Andrew J Souers;Joel D Leverson;Erwin R Boghaert;Scott L Ackler

  • ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor

    Christin Tse;Alexander R. Shoemaker;Jessica Adickes;Mark G. Anderson

  • Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome.

    Barbara Cool;Bradley Zinker;William Chiou;Lemma Kifle

  • ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models

    Cherrie K. Donawho;Yan Luo;Yanping Luo;Thomas D. Penning

  • ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.

    D J Kempf;K C Marsh;J F Denissen;E McDonald

  • ABT-378, a Highly Potent Inhibitor of the Human Immunodeficiency Virus Protease

    Hing L. Sham;Dale J. Kempf;Akhteruzammen Molla;Kennan C. Marsh

  • A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat

    Michael F. Jarvis;Prisca Honore;Char Chang Shieh;Mark Chapman

  • Potent, Orally Active Heterocycle-Based Combretastatin A-4 Analogues: Synthesis, Structure−Activity Relationship, Pharmacokinetics, and In Vivo Antitumor Activity Evaluation

    Le Wang;Keith W. Woods;Qun Li;Kenneth J. Barr

  • Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir.

    D J Kempf;K C Marsh;G Kumar;A D Rodrigues

  • A-740003 [N-(1-{[(Cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a Novel and Selective P2X7 Receptor Antagonist, Dose-Dependently Reduces Neuropathic Pain in the Rat

    Prisca Honore;Diana Donnelly-Roberts;Marian T. Namovic;Gin Hsieh

  • TRPV1 Receptors in the CNS Play a Key Role in Broad-Spectrum Analgesia of TRPV1 Antagonists

    M. Cui;P. Honore;C. Zhong;D. Gauvin

  • Pharmacological Properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological Characterization and Broad Preclinical Efficacy in Cognition and Schizophrenia of a Potent and Selective Histamine H3 Receptor Antagonist

    Gerard B. Fox;Timothy A. Esbenshade;Jia Bao Pan;Richard J. Radek

  • A-425619 [1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a Novel Transient Receptor Potential Type V1 Receptor Antagonist, Relieves Pathophysiological Pain Associated with Inflammation and Tissue Injury in Rats

    Prisca Honore;Carol T Wismer;Joseph P Mikusa;Chang Z Zhu

  • A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

    Margaret A. Phillips;Julie Lotharius;Kennan Marsh;John White

  • Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

    Thomas D Penning;Gui-Dong Zhu;Viraj B Gandhi;Jianchun Gong

  • Discovery of an orally bioavailable small molecule inhibitor of prosurvival B-cell lymphoma 2 proteins.

    Cheol-Min Park;Milan Bruncko;Jessica Adickes;Joy Bauch

  • Pharmacological characterization of A-127722: an orally active and highly potent ETA-selective receptor antagonist.

    T J Opgenorth;A L Adler;S V Calzadilla;W J Chiou

  • Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy.

    Dale J. Kempf;Hing L. Sham;Kennan C. Marsh;Charles A. Flentge

  • Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo.

    Clark A Briggs;David J Anderson;Jorge D Brioni;Jerry J Buccafusco;Jerry J Buccafusco

  • A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

    M. A. Phillips;J. Lotharius;K. Marsh;J. White

Frequent Co-Authors

Hing L. Sham
Hing L. Sham Global Blood Therapeutics (United States)
Saul H. Rosenberg
Saul H. Rosenberg AbbVie (United States)
Prisca Honore
Prisca Honore University of Minnesota
Michael W. Decker
Michael W. Decker Abbott (United Kingdom)
Jacob J. Plattner
Jacob J. Plattner Pfizer (United States)
Gerard B. Fox
Gerard B. Fox Georgetown University Medical Center
Sergio Wittlin
Sergio Wittlin Swiss Tropical and Public Health Institute
Eric F. Johnson
Eric F. Johnson AbbVie (United States)
David J. Anderson
David J. Anderson California Institute of Technology
David A. Fidock
David A. Fidock Columbia University

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