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Hing L. Sham

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Chemistry 59 10202 9224 2836 2333 278 11645
Biology and Biochemistry 60 12003 11055 5151 4617 273 12227

Hing L. Sham publications per year

The chart shows the history of publications by Hing L. Sham between 1979 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Hing L. Sham published across 47 years, from 1979 to 2025, averaging 7.3 papers a year. Output peaked at 29 publications in 1993. 4 of the 343 publications appeared in the last two years.

No. of publications
5 10 15 20 25
Bar chart. Horizontal axis: year, 1979 to 2025. Vertical axis: number of publications, 0 to 29. Peak 29 publications in 1993. 1979: 1 publication 1980: 0 publications 1981: 1 publication 1982: 0 publications 1983: 0 publications 1984: 4 publications 1985: 3 publications 1986: 2 publications 1987: 9 publications 1988: 4 publications 1989: 3 publications 1990: 13 publications 1991: 17 publications 1992: 5 publications 1993: 29 publications 1994: 6 publications 1995: 9 publications 1996: 13 publications 1997: 1 publication 1998: 6 publications 1999: 13 publications 2000: 10 publications 2001: 7 publications 2002: 9 publications 2003: 18 publications 2004: 27 publications 2005: 18 publications 2006: 25 publications 2007: 25 publications 2008: 7 publications 2009: 7 publications 2010: 11 publications 2011: 10 publications 2012: 2 publications 2013: 11 publications 2014: 0 publications 2015: 3 publications 2016: 2 publications 2017: 3 publications 2018: 1 publication 2019: 1 publication 2020: 2 publications 2021: 1 publication 2022: 0 publications 2023: 0 publications 2024: 1 publication 2025: 3 publications
1979 2025

343 publications in total across all disciplines

View publications per year as a table
Hing L. Sham: publications per year, 1979 to 2025
Year Publications
1979 1
1980 0
1981 1
1982 0
1983 0
1984 4
1985 3
1986 2
1987 9
1988 4
1989 3
1990 13
1991 17
1992 5
1993 29
1994 6
1995 9
1996 13
1997 1
1998 6
1999 13
2000 10
2001 7
2002 9
2003 18
2004 27
2005 18
2006 25
2007 25
2008 7
2009 7
2010 11
2011 10
2012 2
2013 11
2014 0
2015 3
2016 2
2017 3
2018 1
2019 1
2020 2
2021 1
2022 0
2023 0
2024 1
2025 3
Total 343
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Hing L. Sham publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Hing L. Sham sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 63 bars. Horizontal axis: publications, 61–80 to 1,295+. Vertical axis: number of scientists, 0 to 1,350. Most scientists, 1,350, have 161–180 publications. The last bar groups every scientist with 1,295 publications or more. The highlighted bar, 261–280 publications, is where this scientist sits. 61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61–80 publications 1,295+

This scientist: 278 publications — 58th percentile

58% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

View publications distribution as a table
Number of Chemistry scientists by publication count, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
Publications Scientists This scientist
61–80 66
81–100 302
101–120 623
121–140 918
141–160 1,218
161–180 1,350
181–200 1,344
201–220 1,281
221–240 1,216
241–260 1,100
261–280 979 278
281–300 939
301–320 764
321–340 643
341–360 628
361–380 522
381–400 459
401–420 397
421–440 327
441–460 270
461–480 265
481–500 252
501–520 201
521–540 185
541–560 148
561–580 148
581–600 132
601–620 114
621–640 104
641–660 91
661–680 92
681–700 73
701–720 57
721–740 54
741–760 67
761–780 45
781–800 46
801–820 39
821–840 32
841–860 36
861–880 29
881–900 26
901–920 24
921–940 14
941–960 23
961–980 28
981–1,000 15
1,001–1,020 29
1,021–1,040 12
1,041–1,060 19
1,061–1,080 12
1,081–1,100 6
1,101–1,120 8
1,121–1,140 12
1,141–1,160 5
1,161–1,180 6
1,181–1,200 14
1,201–1,220 7
1,221–1,240 2
1,241–1,260 6
1,261–1,280 4
1,281–1,294 6
1,295+ 100
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Hing L. Sham D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hing L. Sham sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 61 bars. Horizontal axis: D-Index, 40–41 to 159+. Vertical axis: number of scientists, 0 to 1,051. Most scientists, 1,051, have 56–57 D-Index. The last bar groups every scientist with 159 D-Index or more. The highlighted bar, 58–59 D-Index, is where this scientist sits. 40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40–41 D-Index 159+

This scientist: 59 D-Index — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

View D-Index distribution as a table
Number of Chemistry scientists by D-index, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
D-Index Scientists This scientist
40–41 289
42–43 612
44–45 808
46–47 776
48–49 835
50–51 861
52–53 872
54–55 933
56–57 1,051
58–59 930 59
60–61 882
62–63 834
64–65 731
66–67 775
68–69 683
70–71 646
72–73 561
74–75 501
76–77 437
78–79 388
80–81 354
82–83 292
84–85 275
86–87 254
88–89 235
90–91 185
92–93 192
94–95 155
96–97 163
98–99 125
100–101 105
102–103 105
104–105 112
106–107 88
108–109 68
110–111 69
112–113 65
114–115 79
116–117 61
118–119 44
120–121 37
122–123 40
124–125 33
126–127 26
128–129 34
130–131 35
132–133 25
134–135 27
136–137 17
138–139 16
140–141 20
142–143 20
144–145 15
146–147 9
148–149 9
150–151 16
152–153 11
154–155 9
156–157 3
158 3
159+ 98
Download as CSV

Overview

Hing L. Sham is affiliated with Global Blood Therapeutics in the United States, contributing to research in biomedical and clinical fields. They have published several papers primarily in the Journal of the Canadian Association of Gastroenterology, focusing on topics related to skin exposure, intestinal homeostasis, metabolism, and mucosal-microbe interactions.

Recent papers by Hing L. Sham include:

  • A2 UVB ON SKIN EXPOSURE MODULATES INTESTINAL HOMEOSTASIS IN MICE (2024) - Journal of the Canadian Association of Gastroenterology
  • A69 UVB SKIN EXPOSURE MODULATES INTESTINAL METABOLISM AND HOST DEFENSE (2025) - Journal of the Canadian Association of Gastroenterology
  • A2 USING BIOPSY-DERIVED ORGANOIDS AND GUT-ON-A-CHIP PLATFORM TO DEVELOP A PHYSIOLOGICALLY RELEVANT BACTERIAL INFECTION MODEL (2025) - Journal of the Canadian Association of Gastroenterology
  • A5 USING AIR-LIQUID INTERFACE ORGANOID MONOLAYERS TO DEFINE MUCOSAL-MICROBE DYSFUNCTION IN PATIENTS WITH ULCERATIVE COLITIS (2025) - Journal of the Canadian Association of Gastroenterology

Their research collaborations frequently include coauthors such as:

  • Bruce A. Vallance (4 collaborations)
  • M C Jimenez Sanchez (2 collaborations)
  • Jan Dutz (2 collaborations)
  • Brian Bressler (2 collaborations)
  • Hyungjun Yang (1 collaboration)

Hing L. Sham's work demonstrated interest in using innovative models such as biopsy-derived organoids and gut-on-a-chip platforms to investigate bacterial infections and mucosal-microbe dysfunction. Other studies focus on the biological effects of UVB skin exposure on intestinal health and host defense systems.

The primary venue for their published work is the Journal of the Canadian Association of Gastroenterology, where their recent contributions address gastrointestinal biology with an emphasis on novel methodological approaches and interactions between skin exposure and intestinal responses.

Best Publications

  • ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.

    D J Kempf;K C Marsh;J F Denissen;E McDonald

  • Retroviral protease inhibiting compounds.

    Dale J. Kempf;Daniel W. Norbeck;Hing Leung Sham;Chen Zhao

  • ABT-378, a Highly Potent Inhibitor of the Human Immunodeficiency Virus Protease

    Hing L. Sham;Dale J. Kempf;Akhteruzammen Molla;Kennan C. Marsh

  • Potent, Orally Active Heterocycle-Based Combretastatin A-4 Analogues: Synthesis, Structure−Activity Relationship, Pharmacokinetics, and In Vivo Antitumor Activity Evaluation

    Le Wang;Keith W. Woods;Qun Li;Kenneth J. Barr

  • Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy.

    Dale J. Kempf;Hing L. Sham;Kennan C. Marsh;Charles A. Flentge

  • Polo-like Kinase 2 (PLK2) Phosphorylates α-Synuclein at Serine 129 in Central Nervous System*S⃞

    Unknown

  • Human Serum Attenuates the Activity of Protease Inhibitors toward Wild-Type and Mutant Human Immunodeficiency Virus☆

    Akhteruzzaman Molla;Sudthida Vasavanonda;Gondi Kumar;Hing L. Sham

  • In Vitro Selection and Characterization of Human Immunodeficiency Virus Type 1 Variants with Increased Resistance to ABT-378, a Novel Protease Inhibitor

    Alejandro Carrillo;Kent D. Stewart;Hing L. Sham;Daniel W. Norbeck

  • Aminopyridine-Based c-Jun N-Terminal Kinase Inhibitors with Cellular Activity and Minimal Cross-Kinase Activity†

    Bruce G Szczepankiewicz;Christi Kosogof;Lissa T J Nelson;Gang Liu

  • Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor.

    Gang Zhao;Andrew J Souers;Martin Voorbach;H Doug Falls

  • Design, synthesis, and structural analysis of influenza neuraminidase inhibitors containing pyrrolidine cores.

    Wang Gt;Chen Y;Wang S;Gentles R

  • Discovery of Potent, Selective, Orally Bioavailable Stearoyl-CoA Desaturase 1 Inhibitors

    Gang Liu;John K Lynch;Jennifer Freeman;Bo Liu

  • Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics.

    Zehan Chen;Zhan Xiao;Wen-zhen Gu;John Xue

  • Influenza Neuraminidase Inhibitors: Structure-Based Design of a Novel Inhibitor Series

    Vincent Stoll;Kent D. Stewart;Clarence J. Maring;Steven Muchmore

  • Cyclobut-A and cyclobut-G: broad-spectrum antiviral agents with potential utility for the therapy of AIDS.

    D W Norbeck;E Kern;S Hayashi;W Rosenbrook

  • Synthesis and biological evaluation of 2-indolyloxazolines as a new class of tubulin polymerization inhibitors. Discovery of A-289099 as an orally active antitumor agent.

    Qun Li;Keith W. Woods;Akiyo Claiborne;Stephen L. Gwaltney

  • Inhibition and catalytic mechanism of HIV-1 aspartic protease.

    Unknown

  • Human Chk1 Expression Is Dispensable for Somatic Cell Death and Critical for Sustaining G2 DNA Damage Checkpoint

    Zehan Chen;Zhan Xiao;Jun Chen;Shi-Chung Ng

  • Identification of 2-(4-benzyloxyphenyl)-N- [1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-yl]acetamide, an orally efficacious melanin-concentrating hormone receptor 1 antagonist for the treatment of obesity.

    Andrew J. Souers;Ju Gao;Michael Brune;Eugene Bush

  • Metabolism and disposition of the HIV-1 protease inhibitor lopinavir (ABT-378) given in combination with ritonavir in rats, dogs, and humans.

    Gondi N. Kumar;Venkata K. Jayanti;Marianne K. Johnson;John Uchic

  • X-ray Crystallographic Structure of ABT-378 (Lopinavir) Bound to HIV-1 Protease

    Vincent Stoll;Wenying Qin;Kent D. Stewart;Clarissa Jakob

  • Discovery and structure-activity relationships of piperidinone-and piperidine-constrained phenethylamines as novel, potent, and selective dipeptidyl peptidase IV inhibitors

    Zhonghua Pei;Xiaofeng Li;Thomas W von Geldern;Kenton Longenecker

Frequent Co-Authors

Jacob J. Plattner
Jacob J. Plattner Pfizer (United States)
Saul H. Rosenberg
Saul H. Rosenberg AbbVie (United States)
Kennan C. Marsh
Kennan C. Marsh AbbVie (United States)

External Links

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Scripps Research Institute

Publications: 24

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Publications: 21

Celia A. Schiffer

Celia A. Schiffer

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Publications: 17

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MSD (United States)

Publications: 17

Arun K. Ghosh

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Ahmed Kamal

Ahmed Kamal

Jamia Hamdard

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Nicholas A. Meanwell

Nicholas A. Meanwell

Bristol-Myers Squibb (Germany)

Publications: 14

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Bristol-Myers Squibb (Germany)

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Hong Liu

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Publications: 13

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Chung-Yi Wu

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Publications: 12

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Stephen G. Young

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Jang Yang Chang

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Publications: 11

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Jan Konvalinka

Czech Academy of Sciences

Publications: 11

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