Gerard B. Fox

Overview

Best Publications

• Activation of CPP32-Like Caspases Contributes to Neuronal Apoptosis and Neurological Dysfunction after Traumatic Brain Injury

  Alexander G. Yakovlev;Susan M. Knoblach;Lei Fan;Gerard B. Fox

  763
  Citations

• Pharmacological Properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological Characterization and Broad Preclinical Efficacy in Cognition and Schizophrenia of a Potent and Selective Histamine H3 Receptor Antagonist

  Gerard B. Fox;Timothy A. Esbenshade;Jia Bao Pan;Richard J. Radek

  391
  Citations

• Sustained Sensory/Motor and Cognitive Deficits With Neuronal Apoptosis Following Controlled Cortical Impact Brain Injury in the Mouse

  Gerard B. Fox;Lei Fan;Ryan A. Levasseur;Alan I. Faden

  373
  Citations

• Histamine H3 receptor antagonists: preclinical promise for treating obesity and cognitive disorders.

  Timothy A Esbenshade;Gerard B Fox;Marlon D Cowart

  238
  Citations

• Effects of histamine H3 receptor ligands GT-2331 and ciproxifan in a repeated acquisition avoidance response in the spontaneously hypertensive rat pup

  Gerard B Fox;Jia Bao Pan;Timothy A Esbenshade;Youssef L Bennani

  185
  Citations

• Pharmacological Properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and Selective Histamine H3 Receptor Antagonist with Drug-Like Properties

  Timothy A. Esbenshade;Gerard B. Fox;Kathleen M. Krueger;Thomas R. Miller

  164
  Citations

• 4-(2-[2-(2(R)-Methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and Related 2-Aminoethylbenzofuran H3 Receptor Antagonists Potently Enhance Cognition and Attention

  Marlon Cowart;Ramin Faghih;Michael P. Curtis;Gregory A. Gfesser

  157
  Citations

• Two novel and selective nonimidazole H3 receptor antagonists A-304121 and A-317920: II. In vivo behavioral and neurophysiological characterization.

  Gerard B. Fox;Jia Bao Pan;Richard J. Radek;Angela M. Lewis

  153
  Citations

• Effect of traumatic brain injury on mouse spatial and nonspatial learning in the Barnes circular maze.

  Gerard B. Fox;Lei Fan;Ryan A. LeVASSEUR;Alan I. Faden

  146
  Citations

• Memory consolidation induces a transient and time-dependent increase in the frequency of neural cell adhesion molecule polysialylated cells in the adult rat hippocampus.

  Gerard B. Fox;Alan W. O'Connell;Keith J. Murphy;Ciaran M. Regan

  138
  Citations

• Two Novel and Selective Nonimidazole Histamine H3 Receptor Antagonists A-304121 and A-317920: I. In Vitro Pharmacological Effects

  Timothy A. Esbenshade;Kathleen M. Krueger;Thomas R. Miller;Chae Hee Kang

  125
  Citations

• Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonist.

  Timothy A Esbenshade;Gerard B Fox;Kathleen M Krueger;John L Baranowski

  123
  Citations

• Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist.

  Arthur A. Hancock;Youssef L. Bennani;Eugene N. Bush;Timothy A. Esbenshade

  123
  Citations

• Characterization of a Cannabinoid CB2 Receptor-Selective Agonist, A-836339 [2,2,3,3-Tetramethyl-cyclopropanecarboxylic Acid [3-(2-Methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], Using in Vitro Pharmacological Assays, in Vivo Pain Models, and Pharmacological Magnetic Resonance Imaging

  Betty B. Yao;Gin Hsieh;Anthony V. Daza;Yihong Fan

  123
  Citations

• Enhancement of prepulse inhibition of startle in mice by the H3 receptor antagonists thioperamide and ciproxifan.

  Kaitlin E Browman;Victoria A Komater;Peter Curzon;Lynne E Rueter

  116
  Citations

• The Behavioral Assessment of Sensorimotor Processes in the Mouse: Acoustic Startle, Sensory Gating, Locomotor Activity, Rotarod, and Beam Walking

  Peter Curzon;Min Zhang;Richard J. Radek;Gerard B. Fox

  113
  Citations

• Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test.

  Ana M Basso;Kelly B Gallagher;Natalie A Bratcher;Jorge D Brioni

  111
  Citations

• Default-mode-like network activation in awake rodents.

  Jaymin Upadhyay;Scott J. Baker;Prasant Chandran;Loan Miller

  108
  Citations

• Awake rat pharmacological magnetic resonance imaging as a translational pharmacodynamic biomarker: metabotropic glutamate 2/3 agonist modulation of ketamine-induced blood oxygenation level dependence signals.

  Chih-Liang Chin;Jaymin Upadhyay;Gerard J Marek;Scott J Baker

  108
  Citations

• H3 receptor blockade by thioperamide enhances cognition in rats without inducing locomotor sensitization

  Victoria A. Komater;Kaitlin E. Browman;Peter Curzon;Arthur A. Hancock

  108
  Citations

• Preclinical Characterization of A‐582941: A Novel α7 Neuronal Nicotinic Receptor Agonist with Broad Spectrum Cognition‐Enhancing Properties

  Karin R. Tietje;David J. Anderson;R. Scott Bitner;Eric A. Blomme

  105
  Citations

• Perspectives on cognitive domains, H3 receptor ligands and neurological disease

  Arthur A Hancock;Gerard B Fox

  103
  Citations