World's Best Scientists 2026 revealed!
Adam J. Schwarz

Adam J. Schwarz

D-Index & Metrics

Neuroscience

D-Index
54
Citations
10608
World Ranking
4923
National Ranking
203

Overview

Adam J. Schwarz is affiliated with Qynapse in France and has contributed extensively to research in medicine and neuroscience, with a particular focus on dementia and cognitive impairment. Their work spans interdisciplinary fields, including psychiatry and mental health, physiology, molecular biology, radiology, nuclear medicine, imaging, and cognitive neuroscience.

The scientist's research covers several core topics such as:

  • Dementia and Cognitive Impairment Research
  • Alzheimer's disease research and treatments
  • Functional Brain Connectivity Studies
  • Advanced Neuroimaging Techniques and Applications
  • Mitochondrial Function and Pathology
  • Genetic Neurodegenerative Diseases
  • Neurological Disease Mechanisms and Treatments

Key recent publications authored or co-authored by Schwarz include:

  • Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer's disease (TOMMORROW): a prognostic biomarker study and a phase 3, randomised, double-blind, placebo-controlled trial (2021, The Lancet Neurology)
  • Application of the ATN classification scheme in a population without dementia: Findings from the EPAD cohort (2021, Alzheimer's & Dementia)
  • First-in-Human Assessment of 11C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer (2020, Journal of Nuclear Medicine)
  • Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease (2022, Science Translational Medicine)
  • Biological brain age prediction using machine learning on structural neuroimaging data: Multi-cohort validation against biomarkers of Alzheimer's disease and neurodegeneration stratified by sex (2023, eLife)

Frequent co-authors who have collaborated extensively with Schwarz include:

  • Frederik Barkhof
  • Luigi Lorenzini
  • Juan Domingo Gispert
  • Alle Meije Wink
  • Henk Mutsaerts

Schwarz has published regularly in venues specializing in neuroscience and neurodegenerative diseases, with frequent contributions to:

  • Alzheimer's & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE
  • Neuropsychopharmacology
  • Frontiers in Neurology

The scope of their work incorporates molecular biology aspects along with advanced neuroimaging and nuclear medicine techniques. These methods are applied to understanding the mechanics of Alzheimer's disease and related dementia through longitudinal and cross-sectional studies. Their publications reflect ongoing efforts to identify biomarkers and therapeutic targets to address cognitive decline and neurodegeneration using machine learning and radiotracer imaging.

Best Publications

  • CNVs conferring risk of autism or schizophrenia affect cognition in controls

    Hreinn Stefansson;Andreas Meyer-Lindenberg;Stacy Steinberg;Brynja Magnusdottir

  • Regional profiles of the candidate tau PET ligand 18F-AV-1451 recapitulate key features of Braak histopathological stages.

    Adam J. Schwarz;Peng Yu;Bradley B. Miller;Sergey Shcherbinin

  • Quantitative imaging biomarkers: a review of statistical methods for technical performance assessment.

    David L Raunig;Lisa M McShane;Gene Pennello;Constantine Gatsonis

  • 2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

    Michael W. Weiner;Dallas P. Veitch;Paul S. Aisen;Laurel A. Beckett

  • A stereotaxic MRI template set for the rat brain with tissue class distribution maps and co-registered anatomical atlas: application to pharmacological MRI.

    Adam J. Schwarz;Anne Danckaert;Torsten Reese;Alessandro Gozzi

  • Test–retest reliability of evoked BOLD signals from a cognitive–emotive fMRI test battery

    Michael M. Plichta;Adam J. Schwarz;Oliver Grimm;Katrin Morgen

  • Standardization of analysis sets for reporting results from ADNI MRI data

    Bradley T. Wyman;Danielle J. Harvey;Karen Crawford;Matt A. Bernstein

  • Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease

    Clifford R. Jack;Frederik Barkhof;Matt A. Bernstein;Marc Cantillon

  • Negative edges and soft thresholding in complex network analysis of resting state functional connectivity data

    Adam J. Schwarz;John McGonigle

  • Distributed BOLD and CBV-weighted resting-state networks in the mouse brain

    Francesco Sforazzini;Adam James Schwarz;Alberto Galbusera;Angelo Bifone

  • Large-scale functional connectivity networks in the rodent brain.

    Alessandro Gozzi;Adam J. Schwarz

  • A Neural Switch for Active and Passive Fear

    Alessandro Gozzi;Apar Jain;Aldo Giovanelli;Aldo Giovanelli;Cristina Bertollini

  • Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease

    Niall Colgan;Niall Colgan;Bernard Siow;James M. O'Callaghan;Ian F. Harrison

  • Functional connectivity hubs of the mouse brain.

    Adam Liska;Alberto Galbusera;Adam James Schwarz;Alessandro Gozzi

  • Alzheimer disease brain atrophy subtypes are associated with cognition and rate of decline.

    Shannon L. Risacher;Wesley H. Anderson;Arnaud Charil;Peter F. Castelluccio

  • Frontolimbic atrophy is associated with agitation and aggression in mild cognitive impairment and Alzheimer's disease

    Paula T. Trzepacz;Peng Yu;Phani K. Bhamidipati;Brian Willis

  • Amygdala habituation: a reliable fMRI phenotype.

    Michael M. Plichta;Oliver Grimm;Katrin Morgen;Daniela Mier

  • The classification of volumetric display systems: characteristics and predictability of the image space

    B.G. Blundell;A.J. Schwarz

  • Test–retest reliability of the BOLD pharmacological MRI response to ketamine in healthy volunteers

    S. De Simoni;A. J. Schwarz;A. J. Schwarz;O. G. O'Daly;Andre Marquand

  • Differential effects of antipsychotic and glutamatergic agents on the phMRI response to phencyclidine.

    Alessandro Gozzi;Charles H Large;Adam Schwarz;Simone Bertani

  • 2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

    Michael W. Weiner;Dallas P. Veitch;Paul S. Aisen;Laurel A. Beckett

Frequent Co-Authors

Alessandro Gozzi
Alessandro Gozzi Italian Institute of Technology
Angelo Bifone
Angelo Bifone University of Turin
Andreas Meyer-Lindenberg
Andreas Meyer-Lindenberg Heidelberg University
Alexander Sartorius
Alexander Sartorius Heidelberg University
Michael D. Devous
Michael D. Devous Avid Radiopharmaceuticals
Lino Becerra
Lino Becerra Harvard Medical School
Shannon L. Risacher
Shannon L. Risacher Indiana University
David Borsook
David Borsook Boston Children's Hospital
Clifford R. Jack
Clifford R. Jack Mayo Clinic
Michael W. Weiner
Michael W. Weiner University of California, San Francisco

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