Thomas L. Rothstein

Research.com Recognitions

• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians

Overview

Best Publications

• The role of clonal selection and somatic mutation in autoimmunity.

  Mark J. Shlomchik;Ann Marshak-Rothstein;Claudia B. Wolfowicz;Thomas L. Rothstein

  835
  Citations

• Mouse lymphocytes with and without surface immunoglobulin: preparative scale separation in polystyrene tissue culture dishes coated with specifically purified anti-immunoglobulin.

  Michael G. Mage;Louise L. McHugh;Thomas L. Rothstein

  778
  Citations

• Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells.

  M Wu;H Lee;R E Bellas;S L Schauer

  710
  Citations

• Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70−

  Daniel O. Griffin;Nichol E. Holodick;Thomas L. Rothstein;Thomas L. Rothstein

  694
  Citations

• Disruption of the Cr2 Locus Results in a Reduction in B-1a Cells and in an Impaired B Cell Response to T-Dependent Antigen

  Joseph M Ahearn;Michael B Fischer;Denise Croix;Siegfried Goerg

  590
  Citations

• Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells.

  Thomas L. Rothstein;Julia K. M. Wang;David J. Panka;Linda C. Foote

  530
  Citations

• Regulation of the B cell response to T-dependent antigens by classical pathway complement.

  M B Fischer;M Ma;S Goerg;X Zhou

  433
  Citations

• Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1

  Frank Rosenbauer;Frank Rosenbauer;Bronwyn M. Owens;Li Yu;Joseph R. Tumang

  283
  Citations

• Induction of the transcription factors NF-κB, AP-1 and NF-AT during B cell stimulation through the CD40 receptor

  Delicia A. Francis;James G. Karras;Xiao yan Ke;Ranjan Sen

  278
  Citations

• PD-L2 expression extends beyond dendritic cells/macrophages to B1 cells enriched for VH11/VH12 and phosphatidylcholine binding

  Xuemei Zhong;Joseph R. Tumang;Wenda Gao;Chunyan Bai

  240
  Citations

• Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig.

  Huijuan Xie;T. L. Rothstein

  223
  Citations

• Interleukin-4-mediated Protection of Primary B Cells from Apoptosis through Stat6-dependent Up-regulation of Bcl-xL

  Andrea L. Wurster;Vikki L. Rodgers;Morris F. White;Thomas L. Rothstein

  210
  Citations

• Human B-1 cells take the stage.

  Thomas L. Rothstein;Thomas L. Rothstein;Daniel O. Griffin;Nichol E. Holodick;Tam D. Quach

  209
  Citations

• Signal Transducer and Activator of Transcription-3 (STAT3) Is Constitutively Activated in Normal, Self-renewing B-1 Cells but Only Inducibly Expressed in Conventional B Lymphocytes

  James G. Karras;Zihua Wang;Li Huo;Robert G. Howard

  208
  Citations

• A small CD11b+ human B1 cell subpopulation stimulates T cells and is expanded in lupus

  Daniel O. Griffin;Thomas L. Rothstein;Thomas L. Rothstein

  198
  Citations

• Eμ-BRD2 transgenic mice develop B-cell lymphoma and leukemia

  Rebecca J. Greenwald;Joseph R. Tumang;Anupama Sinha;Nicolas Currier

  196
  Citations

• Reciprocal generation of Th1/Th17 and Treg cells by B1 and B2 B cells

  Xuemei Zhong;Wenda Gao;Nicolas Degauque;Chunyan Bai

  196
  Citations

• Induction of bcl-x by CD40 engagement rescues sIg-induced apoptosis in murine B cells.

  Zihua Wang;J. G. Karras;R. G. Howard;T. L. Rothstein

  184
  Citations

• Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis

  Georg F. Weber;Georg F. Weber;Benjamin G. Chousterman;Ingo Hilgendorf;Clinton S. Robbins

  173
  Citations

• A novel gene coding for a Fas apoptosis inhibitory molecule (FAIM) isolated from inducibly Fas-resistant B lymphocytes.

  Thomas J. Schneider;Gavin M. Fischer;Terrence J. Donohoe;Thomas P. Colarusso

  167
  Citations