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Thomas R. Kleyman

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
14011
World Ranking
8316
National Ranking
3755

Thomas R. Kleyman publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Thomas R. Kleyman sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 313 publications — 80th percentile

80% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Thomas R. Kleyman D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Thomas R. Kleyman sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 67 D-Index — 59th percentile

59% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Thomas R. Kleyman is affiliated with the University of Pittsburgh in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans numerous subfields, including molecular biology, endocrinology, diabetes and metabolism, nutrition and dietetics, physiology, and pulmonary and respiratory medicine.

The scientist's research topics focus primarily on ion transport and channel regulation, hormonal regulation and hypertension, ion channel regulation and function, and sodium intake and health. Additional areas of investigation include electrolyte and hormonal disorders, renal and related cancers, and erythrocyte function and pathophysiology.

Thomas R. Kleyman has a selection of recent papers published in distinguished venues. Notable publications include:

  • Hypertension (2021), published in Circulation Research
  • Epithelial Sodium Channel and Salt-Sensitive Hypertension (2021), published in Hypertension
  • DC ENaC-Dependent Inflammasome Activation Contributes to Salt-Sensitive Hypertension (2022), published in Circulation Research
  • ENaC in Salt-Sensitive Hypertension: Kidney and Beyond (2020), published in Current Hypertension Reports
  • Intercalated cell BKα subunit is required for flow-induced K+ secretion (2020), published in JCI Insight

Some of the frequent coauthors collaborating with Thomas R. Kleyman include Annet Kirabo, Stephanie M. Mutchler, Evan C. Ray, Allison L. Marciszyn, and Shaohu Sheng. These collaborations highlight a consistent research network centered on topics related to ion channels and hypertension.

The researcher often publishes in venues such as The FASEB Journal, Journal of the American Society of Nephrology, Physiology, American Journal of Physiology-Renal Physiology, and Physiological Reports. These journals reflect the interdisciplinary nature of their studies, bridging molecular biology, physiology, and clinical medicine.

Best Publications

  • Amiloride and its analogs as tools in the study of ion transport.

    Thomas R. Kleyman;Edward J. Cragoe;Edward J. Cragoe

  • Epithelial Sodium Channels Are Activated by Furin-dependent Proteolysis

    Rebecca P. Hughey;James B. Bruns;Carol L. Kinlough;Keri L. Harkleroad

  • Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit.

    James B. Bruns;Marcelo D. Carattino;Shaohu Sheng;Ahmad B. Maarouf

  • ENaC at the Cutting Edge: Regulation of Epithelial Sodium Channels by Proteases

    Thomas R. Kleyman;Marcelo D. Carattino;Rebecca P. Hughey

  • Maturation of the Epithelial Na+ Channel Involves Proteolytic Processing of the α- and γ-Subunits

    Rebecca P. Hughey;Gunhild M. Mueller;James B. Bruns;Carol L. Kinlough

  • Flow-dependent K+ secretion in the cortical collecting duct is mediated by a maxi-K channel.

    Craig B. Woda;Alvina Bragin;Thomas R. Kleyman;Lisa M. Satlin

  • Subunit Stoichiometry of the Epithelial Sodium Channel

    Farhad Kosari;Shaohu Sheng;Jinqing Li;Don On D. Mak

  • Epithelial Na(+) channels are regulated by flow.

    Lisa M. Satlin;Shaohu Sheng;Craig B. Woda;Thomas R. Kleyman

  • Aldosterone alters the open probability of amiloride-blockable sodium channels in A6 epithelia.

    A. E. Kemendy;T. R. Kleyman;D. C. Eaton

  • Plasmin Activates Epithelial Na+ Channels by Cleaving the γ Subunit

    Christopher J. Passero;Gunhild M. Mueller;Helbert Rondon-Berrios;Stevan P. Tofovic

  • Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition

    Shaohu Sheng;Marcelo D. Carattino;James B. Bruns;Rebecca P. Hughey

  • Differential effects of Hsc70 and Hsp70 on the intracellular trafficking and functional expression of epithelial sodium channels

    Samuel B. Goldfarb;Ossama B. Kashlan;Jeffrey N. Watkins;Laurence Suaud

  • Distinct Pools of Epithelial Sodium Channels Are Expressed at the Plasma Membrane

    Rebecca P. Hughey;James B. Bruns;Carol L. Kinlough;Thomas R. Kleyman

  • Epithelial Na+ Channels Are Activated by Laminar Shear Stress

    Marcelo D. Carattino;Shaohu Sheng;Thomas R. Kleyman

  • Brief report: trimethoprim-induced hyperkalemia in a patient with AIDS.

    Michael J. Choi;Pedro C. Fernandez;Pedro C. Fernandez;Pedro C. Fernandez;Asit Patnaik;Brigitte Coupaye-Gerard

  • Epithelial Sodium Channel Inhibition by AMP-activated Protein Kinase in Oocytes and Polarized Renal Epithelial Cells

    Marcelo D. Carattino;Robert S. Edinger;Heather J. Grieser;Rosalee Wise

  • ENaC structure and function in the wake of a resolved structure of a family member.

    Ossama B. Kashlan;Thomas R. Kleyman

  • Role of epithelial sodium channels and their regulators in hypertension

    Rama Soundararajan;David Pearce;Rebecca P. Hughey;Thomas R. Kleyman

  • Airway Surface Liquid Volume Regulates ENaC by Altering the Serine Protease-Protease Inhibitor Balance A MECHANISM FOR SODIUM HYPERABSORPTION IN CYSTIC FIBROSIS

    Mike M. Myerburg;Michael B. Butterworth;Erin E. McKenna;Kathryn W. Peters

  • Proteolytic Processing of the Epithelial Sodium Channel γ Subunit Has a Dominant Role in Channel Activation

    Marcelo D. Carattino;Rebecca P. Hughey;Thomas R. Kleyman

Frequent Co-Authors

Thomas Kieber-Emmons
Thomas Kieber-Emmons University of Arkansas for Medical Sciences
Joseph M. Pilewski
Joseph M. Pilewski University of Pittsburgh
Douglas C. Eaton
Douglas C. Eaton Emory University
J. Kevin Foskett
J. Kevin Foskett University of Pennsylvania
Bruce A. Molitoris
Bruce A. Molitoris Indiana University
Uwe Schlattner
Uwe Schlattner Grenoble Alpes University
Gerard Apodaca
Gerard Apodaca University of Pittsburgh
Horacio F. Cantiello
Horacio F. Cantiello Harvard University
James D. Stockand
James D. Stockand The University of Texas Health Science Center at San Antonio
David Pearce
David Pearce Northumbria University

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Best Scientists Citing Thomas R. Kleyman

Douglas C. Eaton

Douglas C. Eaton

Emory University

Publications: 56

Dale J. Benos

Dale J. Benos

University of Alabama at Birmingham

Publications: 45

Bernard C. Rossier

Bernard C. Rossier

University of Lausanne

Publications: 41

Lawrence G. Palmer

Lawrence G. Palmer

Cornell University

Publications: 39

Wen-Hui Wang

Wen-Hui Wang

New York Medical College

Publications: 36

James D. Stockand

James D. Stockand

The University of Texas Health Science Center at San Antonio

Publications: 36

Sadis Matalon

Sadis Matalon

University of Alabama at Birmingham

Publications: 26

Catherine M. Fuller

Catherine M. Fuller

University of Alabama at Birmingham

Publications: 24

Robert Tarran

Robert Tarran

University of North Carolina at Chapel Hill

Publications: 23

M. Jackson Stutts

M. Jackson Stutts

University of North Carolina at Chapel Hill

Publications: 23

Richard C. Boucher

Richard C. Boucher

University of North Carolina at Chapel Hill

Publications: 23

Florian Lang

Florian Lang

University of Tübingen

Publications: 22

Ole Petter Rekvig

Ole Petter Rekvig

University of Tromsø - The Arctic University of Norway

Publications: 20

Frans H. H. Leenen

Frans H. H. Leenen

University of Ottawa

Publications: 20

Alain Vandewalle

Alain Vandewalle

Inserm

Publications: 18

Chris M. Wood

Chris M. Wood

University of British Columbia

Publications: 18

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