2013 - Fellow of the American Association for the Advancement of Science (AAAS)
His scientific interests lie mostly in Cell biology, Endoplasmic reticulum, Gating, Biochemistry and Voltage-dependent calcium channel. His Cell biology study incorporates themes from Inositol trisphosphate receptor and Cystic fibrosis transmembrane conductance regulator. His Inositol trisphosphate receptor research is multidisciplinary, incorporating perspectives in Bcl-xL and Calcium signaling.
His Endoplasmic reticulum research incorporates elements of Cell culture, Signal transduction and Inositol. Biochemistry is frequently linked to Biophysics in his study. His work in Biophysics addresses subjects such as Patch clamp, which are connected to disciplines such as Ion channel.
His primary areas of study are Cell biology, Biophysics, Gating, Endoplasmic reticulum and Biochemistry. The study incorporates disciplines such as Inositol trisphosphate receptor, Ion channel, Cystic fibrosis transmembrane conductance regulator and Voltage-dependent calcium channel in addition to Cell biology. His studies in Biophysics integrate themes in fields like Cytoplasm, Calcium, Extracellular, Membrane and Patch clamp.
His research integrates issues of Xenopus, Adenosine triphosphate, ATP synthase alpha/beta subunits, Ligand-gated ion channel and Allosteric regulation in his study of Gating. The concepts of his Endoplasmic reticulum study are interwoven with issues in Programmed cell death, Ionomycin, Intracellular and Inositol. His study in the field of Protein subunit and Cell also crosses realms of Ammonia transporter, Ammonium and Chloride.
His primary areas of investigation include Cell biology, Biophysics, Ion channel, Mitochondrion and Receptor. His Cell biology study combines topics in areas such as Flux and Biochemistry. His work deals with themes such as Calcium, Cytoplasm, Crosstalk and Channel gating, which intersect with Biophysics.
J. Kevin Foskett combines subjects such as Patch clamp and Voltage-dependent calcium channel with his study of Ion channel. Ca2 binding protein and Peripheral is closely connected to Gating in his research, which is encompassed under the umbrella topic of Receptor. His Calcium signaling study integrates concerns from other disciplines, such as STIM1, Inositol trisphosphate receptor and Presenilin.
J. Kevin Foskett mainly focuses on Cell biology, Ion channel, Voltage-dependent calcium channel, Mitochondrion and Calcium signaling. He works in the field of Cell biology, namely Endoplasmic reticulum. His Ion channel research is multidisciplinary, relying on both Gating and Patch clamp.
His Voltage-dependent calcium channel study also includes
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Inositol Trisphosphate Receptor Ca2+ Release Channels
J. Kevin Foskett;Carl White;King-Ho Cheung;Don-On Daniel Mak.
Physiological Reviews (2007)
Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria
César Cárdenas;Russell A. Miller;Ian Smith;Thi Bui.
MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.
Karthik Mallilankaraman;Patrick Doonan;César Cárdenas;César Cárdenas;Harish C. Chandramoorthy.
MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
Karthik Mallilankaraman;César Cárdenas;Patrick J. Doonan;Harish C. Chandramoorthy.
Nature Cell Biology (2013)
Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating.
King-Ho Cheung;Diana Shineman;Marioly Müller;César Cárdenas.
The endoplasmic reticulum gateway to apoptosis by Bcl-XL modulation of the InsP3R
Carl White;Chi Li;Jun Yang;Nataliya B. Petrenko.
Nature Cell Biology (2005)
CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes
Akiyuki Taruno;Valérie Vingtdeux;Makoto Ohmoto;Zhongming Ma.
Inositol 1,4,5-tris-phosphate activation of inositol tris-phosphate receptor Ca2+ channel by ligand tuning of Ca2+ inhibition
Don On Daniel Mak;Sean Mcbride;J. Kevin Foskett.
Proceedings of the National Academy of Sciences of the United States of America (1998)
A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk
Ute Dreses-Werringloer;Jean Charles Lambert;Valérie Vingtdeux;Haitian Zhao.
Regulation of cystic fibrosis transmembrane conductance regulator single-channel gating by bivalent PDZ-domain-mediated interaction.
Viswanathan Raghuram;Don-On Daniel Mak;J. Kevin Foskett.
Proceedings of the National Academy of Sciences of the United States of America (2001)
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