World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
29236
World Ranking
17384
National Ranking
7143

Overview

Philippe Marambaud is affiliated with the Feinstein Institute for Medical Research in the United States. Their research primarily focuses on medicine, with significant contributions across genetics, physiology, molecular biology, neurology, and cellular and molecular neuroscience. The areas of study reflect a multidisciplinary approach to complex biological and medical problems.

The scientist's work engages deeply with several main topics, including:

  • Vascular Anomalies and Treatments
  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Vascular Malformations and Hemangiomas
  • Protease and Inhibitor Mechanisms
  • Cerebrovascular and genetic disorders
  • Cell Adhesion Molecules Research

Marambaud has published numerous papers, some recent ones being:

  • "Extracellular CIRP Activates the IL-6Rα/STAT3/Cdk5 Pathway in Neurons" (2021, Molecular Neurobiology)
  • "ANG2 Blockade Diminishes Proangiogenic Cerebrovascular Defects Associated With Models of Hereditary Hemorrhagic Telangiectasia" (2023, Arteriosclerosis Thrombosis and Vascular Biology)
  • "Randomized, double-blind, placebo-controlled, crossover trial of oral doxycycline for epistaxis in hereditary hemorrhagic telangiectasia" (2022, Orphanet Journal of Rare Diseases)
  • "Oxidative stress-induced MMP- and γ-secretase-dependent VE-cadherin processing is modulated by the proteasome and BMP9/10" (2023, Scientific Reports)
  • "Molecular and Pharmacological Modulation of CALHM1 Promote Neuroprotection against Oxygen and Glucose Deprivation in a Model of Hippocampal Slices" (2020, Cells)

The most frequent publication venues for Marambaud include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Neurobiology
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Orphanet Journal of Rare Diseases
  • Scientific Reports

Frequent collaborators in their research efforts are:

  • Santiago Ruiz
  • Archna Sharma
  • Max Brenner
  • Ping Wang
  • Aya Nomura-Kitabayashi

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Resveratrol Promotes Clearance of Alzheimer's Disease Amyloid-β Peptides

    Philippe Marambaud;Haitian Zhao;Peter Davies

  • A presenilin‐1/γ‐secretase cleavage releases the E‐cadherin intracellular domain and regulates disassembly of adherens junctions

    Philippe Marambaud;Junichi Shioi;Geo Serban;Anastasios Georgakopoulos

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism

    Valérie Vingtdeux;Luca Giliberto;Haitian Zhao;Pallavi Chandakkar

  • A CBP Binding Transcriptional Repressor Produced by the PS1/ϵ-Cleavage of N-Cadherin Is Inhibited by PS1 FAD Mutations

    Philippe Marambaud;Paul H Wen;Anindita Dutt;Junichi Shioi

  • CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes

    Akiyuki Taruno;Valérie Vingtdeux;Makoto Ohmoto;Zhongming Ma

  • TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity.

    Fusheng Chen;Hiroshi Hasegawa;Hiroshi Hasegawa;Gerold Schmitt-Ulms;Toshitaka Kawarai

  • Resveratrol mitigates lipopolysaccharide- and Aβ-mediated microglial inflammation by inhibiting the TLR4/NF-κB/STAT signaling cascade.

    Hemachander Capiralla;Valérie Vingtdeux;Haitian Zhao;Roman Sankowski

  • A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk

    Ute Dreses-Werringloer;Jean Charles Lambert;Valérie Vingtdeux;Haitian Zhao

  • Calcium signaling in neurodegeneration

    Philippe Marambaud;Philippe Marambaud;Ute Dreses-Werringloer;Valérie Vingtdeux

  • AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies.

    Valérie Vingtdeux;Peter Davies;Peter Davies;Dennis W. Dickson;Philippe Marambaud;Philippe Marambaud

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Therapeutic potential of resveratrol in Alzheimer's disease

    Valérie Vingtdeux;Ute Dreses-Werringloer;Haitian Zhao;Peter J. Davies;Peter J. Davies

  • Presenilin-1 Forms Complexes with the Cadherin/Catenin Cell–Cell Adhesion System and Is Recruited to Intercellular and Synaptic Contacts

    Anastasios Georgakopoulos;Philippe Marambaud;Spiros Efthimiopoulos;Junichi Shioi

  • Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation.

    Valérie Vingtdeux;Pallavi Chandakkar;Haitian Zhao;Cristina d'Abramo

  • Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex.

    Lia Baki;Philippe Marambaud;Spiros Efthimiopoulos;Anastasios Georgakopoulos

  • Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β.

    Tao Ma;Yiran Chen;Valerie Vingtdeux;Haitian Zhao

  • Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid beta peptides: their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiopathy cases.

    Hélène Barelli;Anthony Lebeau;Jean Vizzavona;Pia Delaere

Frequent Co-Authors

Peter Davies
Peter Davies University of Queensland
Frédéric Checler
Frédéric Checler Grenoble Alpes University
Nikolaos K. Robakis
Nikolaos K. Robakis Icahn School of Medicine at Mount Sinai
J. Kevin Foskett
J. Kevin Foskett University of Pennsylvania
Ping Wang
Ping Wang Feinstein Institute for Medical Research
Christine N. Metz
Christine N. Metz Feinstein Institute for Medical Research
Evelina Gatti
Evelina Gatti Aix-Marseille University
Jean Martinez
Jean Martinez University of Montpellier
Sergio Lavandero
Sergio Lavandero University of Chile
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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