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Biology and Biochemistry

D-Index
76
Citations
17592
World Ranking
5126
National Ranking
387

Overview

Colin W. Taylor is affiliated with the University of Cambridge in the United Kingdom. Their research primarily focuses on the biochemical and molecular biological aspects of cellular processes, with notable contributions in neuroscience.

The scientist has published extensively within several subfields of study, including Molecular Biology, Physiology, Cell Biology, Sensory Systems, and Cellular and Molecular Neuroscience. Their work addresses complex topics such as ion channel regulation and function, ion channels and receptors, cellular transport and secretion, calcium signaling and nucleotide metabolism, protein kinase regulation and GTPase signaling, carbohydrate chemistry and synthesis, and lipid membrane structure and behavior.

Frequent co-authors collaborating with Colin W. Taylor include Peace Atakpa-Adaji, Ana M. Rossi, Barry V. L. Potter, Nagendra Babu Thillaiappan, and Adelina Ivanova.

The scientist's recent papers cover various important aspects of calcium signaling and ion channel function. These include:

  • KRAP tethers IP3 receptors to actin and licenses them to evoke cytosolic Ca2+ signals (2021), published in Nature Communications
  • Reliable measurement of free Ca2+ concentrations in the ER lumen using Mag-Fluo-4 (2020), published in Cell Calcium
  • The store-operated Ca2+ entry complex comprises a small cluster of STIM1 associated with one Orai1 channel (2021), published in Proceedings of the National Academy of Sciences
  • Regulation of store-operated Ca2+ entry by IP3 receptors independent of their ability to release Ca2+ (2023), published in eLife
  • iRhom pseudoproteases regulate ER stress-induced cell death through IP3 receptors and BCL-2 (2022), published in Nature Communications

Publications frequently appear in venues such as Nature Communications, Cell Reports, the Journal of Medicinal Chemistry, Cell Calcium, and Molecular Cell.

Colin W. Taylor's main fields of study reflect a strong emphasis on Biochemistry, Genetics, and Molecular Biology, complemented by work in Neuroscience. The detailed exploration of calcium signaling and ion channel behavior integrates their expertise across these scientific domains.

Best Publications

  • Spontaneous calcium release from inositol trisphosphate-sensitive calcium stores

    Ludwig Missiaen;Colin W. Taylor;Michael J. Berridge

  • T-Level Downstaging and Complete Pathologic Response After Preoperative Chemoradiation for Advanced Rectal Cancer Result in Decreased Recurrence and Improved Disease-Free Survival

    George Theodoropoulos;W. E. Wise;A. Padmanabhan;B. A. Kerner

  • Analysis of protein-ligand interactions by fluorescence polarization

    Ana M Rossi;Colin W Taylor

  • Expression of inositol trisphosphate receptors.

    C.W. Taylor;A.A. Genazzani;S.A. Morris

  • The role of G proteins in transmembrane signalling.

    C W Taylor

  • The thiol reagent, thimerosal, evokes Ca2+ spikes in HeLa cells by sensitizing the inositol 1,4,5-trisphosphate receptor.

    Martin D. Bootman;Colin W. Taylor;Michael J. Berridge

  • IP3 receptors and their regulation by calmodulin and cytosolic Ca2

    C.W Taylor;A.J Laude

  • IP3 Receptors: Toward Understanding Their Activation

    Colin W. Taylor;Stephen C. Tovey

  • A non-capacitative pathway activated by arachidonic acid is the major Ca2+ entry mechanism in rat A7r5 smooth muscle cells stimulated with low concentrations of vasopressin

    Lisa M. Broad;Toby R. Cannon;Colin W. Taylor

  • Ca2+ entry through plasma membrane IP3 receptors.

    Olivier Dellis;Skarlatos G. Dedos;Stephen C. Tovey;Taufiq-Ur-Rahman

  • Paclitaxel affects cytosolic calcium signals by opening the mitochondrial permeability transition pore.

    Jackie F. Kidd;Mary F. Pilkington;Michael J. Schell;Kevin E. Fogarty

  • Clustering of InsP3 receptors by InsP3 retunes their regulation by InsP3 and Ca2

    Taufiq-Ur-Rahman;Alexander Skupin;Martin Falcke;Colin W. Taylor

  • Inositol trisphosphate receptors: Ca2+-modulated intracellular Ca2+ channels

    Colin W Taylor

  • Evidence suggesting that a novel guanine nucleotide regulatory protein couples receptors to phospholipase C in exocrine pancreas.

    JE Merritt;CW Taylor;RP Rubin;Jr Jw Putney

  • How Does Intracellular Ca2+ Oscillate: By Chance or by the Clock?

    Alexander Skupin;Helmut Kettenmann;Ulrike Winkler;Maria Wartenberg

  • Structure and function of inositol triphosphate receptors

    Colin W. Taylor;Alan Richardson

  • Pharmacological analysis of intracellular Ca2+ signalling: problems and pitfalls

    Colin W. Taylor;Lisa M. Broad

  • IP3 receptors: the search for structure

    Colin W. Taylor;Paula C.A. da Fonseca;Edward P. Morris

  • Cooperative activation of IP3 receptors by sequential binding of IP3 and Ca2+ safeguards against spontaneous activity

    Jonathan S. Marchant;Colin W. Taylor

  • Inositol Trisphosphate and Calcium Signaling

    M.J. Berridge;C.W. Taylor

Frequent Co-Authors

Barry V. L. Potter
Barry V. L. Potter University of Oxford
James W. Putney
James W. Putney National Institutes of Health
Geoffrey L. Smith
Geoffrey L. Smith University of Oxford
Sandip Patel
Sandip Patel University College London
Michael J. Berridge
Michael J. Berridge Babraham Institute
Martin D. Bootman
Martin D. Bootman The Open University
Alan Richardson
Alan Richardson Commonwealth Scientific and Industrial Research Organisation
Sarah C. R. Lummis
Sarah C. R. Lummis University of Cambridge
Antony Galione
Antony Galione University of Oxford
Satoshi Shuto
Satoshi Shuto Hokkaido University

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