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Satoshi Shuto

Satoshi Shuto

D-Index & Metrics

Chemistry

D-Index
55
Citations
9223
World Ranking
12308
National Ranking
923

Overview

Satoshi Shuto is affiliated with Hokkaido University in Japan. Their research spans several fields, primarily focusing on biochemistry, genetics, and molecular biology as well as medicine.

The main fields of study for Shuto include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their subfields of expertise cover:

  • Molecular Biology
  • Organic Chemistry
  • Immunology
  • Physiology
  • Cellular and Molecular Neuroscience

Shuto's research topics include:

  • Chemical Synthesis and Analysis
  • Neuroscience and Neuropharmacology Research
  • Fatty Acid Research and Health
  • Stress Responses and Cortisol
  • Eicosanoids and Hypertension Pharmacology
  • Peroxisome Proliferator-Activated Receptors
  • RNA and protein synthesis mechanisms

Among the recent papers authored or co-authored by Satoshi Shuto are:

  • Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine-Loaded Lipid Nanoparticles (2022), published in Advanced Healthcare Materials
  • Discovery of [1,2,4]Triazolo[1,5-a]pyridine Derivatives as Potent and Orally Bioavailable RORγt Inverse Agonists (2020), published in ACS Medicinal Chemistry Letters
  • Design and Synthesis of Benzene Congeners of Resolvin E2, a Proresolving Lipid Mediator, as Its Stable Equivalents (2020), published in ACS Medicinal Chemistry Letters
  • Synthesis of Resolvin E3, a Proresolving Lipid Mediator, and Its Deoxy Derivatives: Identification of 18-Deoxy-resolvin E3 as a Potent Anti-Inflammatory Agent (2020), published in The Journal of Organic Chemistry
  • Resolvin E1 Attenuates Chronic Pain-Induced Depression-Like Behavior in Mice: Possible Involvement of Chemerin Receptor ChemR23 (2021), published in Biological and Pharmaceutical Bulletin

Frequent co-authors working with Shuto include:

  • Mizuki Watanabe
  • Hayato Fukuda
  • Koichi Fujiwara
  • Kohei Ishimura
  • Satoshi Deyama

Prominent venues where Shuto's work has appeared encompass:

  • ACS Medicinal Chemistry Letters
  • The Journal of Organic Chemistry
  • Bioorganic & Medicinal Chemistry Letters
  • Organic Letters
  • Proceedings for Annual Meeting of The Japanese Pharmacological Society

Best Publications

  • Rolling Circle Translation of Circular RNA in Living Human Cells

    Naoko Abe;Ken Matsumoto;Mizuki Nishihara;Yukiko Nakano

  • Highly α- and β-Selective Radical C-Glycosylation Reactions Using a Controlling Anomeric Effect Based on the Conformational Restriction Strategy. A Study on the Conformation−Anomeric Effect− Stereoselectivity Relationship in Anomeric Radical Reactions

    Hiroshi Abe;Satoshi Shuto;Akira Matsuda

  • Nucleosides and nucleotides. 185. Synthesis and biological activities of 4'alpha-C-branched-chain sugar pyrimidine nucleosides.

    Makoto Nomura;Satoshi Shuto;Motohiro Tanaka;Takuma Sasaki

  • A facile one-step synthesis of 5'-phosphatidylnucleosides by an enzymatic two-phase reaction

    Satoshi Shuto;Shigeru Ueda;Shigeyuki Imamura;Kiyofumi Fukukawa

  • Conformational Restriction by Repulsion between Adjacent Substituents on a Cyclopropane Ring: Design and Enantioselective Synthesis of 1-Phenyl-2-(1-aminoalkyl)-N,N-diethylcyclopropanecarboxamides as Potent NMDA Receptor Antagonists

    Satoshi Shuto;Shizuka Ono;Yukako Hase;Noriko Kamiyama

  • Synthesis and characterization of a series of highly fluorogenic substrates for glutathione transferases, a general strategy.

    Jie Zhang;Aya Shibata;Mika Ito;Satoshi Shuto

  • Nucleosides and nucleotides. 183. Synthesis of 4′ α-branched thymidines as a new type of antiviral agent

    Isamu Sugimoto;Satoshi Shuto;Shuichi Mori;Shiro Shigeta

  • Development of versatile cis- and trans-dicarbon-substituted chiral cyclopropane units: synthesis of (1S,2R)- and (1R,2R)-2-aminomethyl-1-(1H-imidazol-4-yl)cyclopropanes and their enantiomers as conformationally restricted analogues of histamine.

    Yuji Kazuta;and Akira Matsuda;Satoshi Shuto

  • The First Synthesis of Herbicidin B. Stereoselective Construction of the Tricyclic Undecose Moiety by a Conformational Restriction Strategy Using Steric Repulsion between Adjacent Bulky Silyl Protecting Groups on a Pyranose Ring

    Satoshi Ichikawa;and Satoshi Shuto;Akira Matsuda

  • A facile enzymatic synthesis of 5'-(3-sn-phosphatidyl)nucleosides and their antileukemic activities.

    Satoshi Shuto;Hiromichi Itoh;Shigeru Ueda;Shigeyuki Imamura

  • Sulfur Modification of Au via Treatment with Piranha Solution Provides Low-Pd Releasing and Recyclable Pd Material, SAPd

    Naoyuki Hoshiya;Masahiko Shimoda;Hideki Yoshikawa;Yoshiyuki Yamashita

  • Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure.

    Yuji Kazuta;Kazufumi Hirano;Kentaro Natsume;Shizuo Yamada

  • Palladium-Catalyzed Arylation of Cyclopropanes via Directing Group-Mediated C(sp3)–H Bond Activation To Construct Quaternary Carbon Centers: Synthesis of cis- and trans-1,1,2-Trisubstituted Chiral Cyclopropanes

    Naoyuki Hoshiya;Takaaki Kobayashi;Mitsuhiro Arisawa;Satoshi Shuto

  • New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents.

    Satoshi Shuto;Takumi Obara;Minoru Toriya;Mitsuaki Hosoya

  • Nucleosides and nucleotides. 175. Structural requirements of the sugar moiety for the antitumor activities of new nucleoside antimetabolites, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and -uracil1

    Hideshi Hattori;Eisuke Nozawa;Tomoharu Iino;Yuichi Yoshimura

  • (.+-.)-(Z)-2-(Aminomethyl)-1-phenylcyclopropanecarboxamide Derivatives as a New Prototype of NMDA Receptor Antagonists

    Satoshi Shuto;Hironao Takada;Daisuke Mochizuki;Ryuichi Tsujita

  • Total Synthesis of Cyclic ADP-carbocyclic-ribose, a Stable Mimic of Ca2+-Mobilizing Second Messenger Cyclic ADP-Ribose1

    Satoshi Shuto;Masayoshi Fukuoka;Andrzej Manikowsky;Yoshihito Ueno

  • Construction of a cis-Cyclopropane via Reductive Radical Decarboxylation. Enantioselective Synthesis of cis- and trans-1-Arylpiperazyl-2-phenylcyclopropanes Designed as Antidopaminergic Agents

    Kazuya Yamaguchi;Yuji Kazuta;Hiroshi Abe;and Akira Matsuda

  • Anti-neovascular therapy by liposomal DPP-CNDAC targeted to angiogenic vessels.

    Tomohiro Asai;Kosuke Shimizu;Masami Kondo;Koichi Kuromi

  • Nucleosides and nucleotides. 132. Synthesis and biological evaluations of ring-expanded oxetanocin analogues: Purine and pyrimidine analogues of 1,4-anhydro-2-deoxy-d-arabitol and 1,4-anhydro-2-deoxy-3-hydroxymethyl-d-arabitol

    Akio Kakefuda;Satoshi Shuto;Takemitsu Nagahata;Jun-ichi Seki

  • 1,2,3-Triazole-containing uracil derivatives with excellent pharmacokinetics as a novel class of potent human deoxyuridine triphosphatase inhibitors.

    Hitoshi Miyakoshi;Seiji Miyahara;Tatsushi Yokogawa;Kanji Endoh

Frequent Co-Authors

Akira Matsuda
Akira Matsuda Juntendo University
Hiroshi Abe
Hiroshi Abe Nagoya University
Barry V. L. Potter
Barry V. L. Potter University of Oxford
Haruhiro Higashida
Haruhiro Higashida Kanazawa University
Shizuo Yamada
Shizuo Yamada University of Shizuoka
Shiro Shigeta
Shiro Shigeta Fukushima Medical University
Masanori Baba
Masanori Baba Kagoshima University
Tadashi Matsuda
Tadashi Matsuda Hokkaido University
Bengt Mannervik
Bengt Mannervik Stockholm University

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