2015 - Fellow, National Academy of Inventors
Chung K. Chu focuses on Stereochemistry, Virus, Nucleoside, Virology and Biochemistry. His study in Stereochemistry is interdisciplinary in nature, drawing from both Uridine, Cytosine, Cytotoxicity, Structure–activity relationship and Chemical synthesis. The Cytosine study combines topics in areas such as Uracil and Pyrimidine.
The concepts of his Virus study are interwoven with issues in Biological activity and Enantiomer. His study in the fields of Nucleoside analogue under the domain of Nucleoside overlaps with other disciplines such as Monkeypox virus, Monkeypox and Cowpox virus. His Virology research integrates issues from Molecular biology and Reverse transcriptase.
His scientific interests lie mostly in Stereochemistry, Nucleoside, Virology, Virus and Pyrimidine. The various areas that he examines in his Stereochemistry study include Cytosine, Nucleic acid, Chemical synthesis and Purine. His research in Nucleoside intersects with topics in Prodrug, Pharmacology and Biological activity.
His primary area of study in Virology is in the field of Hepatitis B virus. Chung K. Chu has included themes like Molecular biology, In vitro and Uracil in his Virus study. Chung K. Chu works mostly in the field of Biochemistry, limiting it down to concerns involving Reverse transcriptase and, occasionally, Nucleotidyltransferase and Active site.
Chung K. Chu mainly investigates Stereochemistry, Nucleoside, Virology, Virus and Biochemistry. His Stereochemistry research includes themes of Enzyme, Purine, Active site and Chemical synthesis. His Nucleoside study integrates concerns from other disciplines, such as Guanosine, Biological activity, In vitro and Pharmacology.
His Virology study deals with Resistance mutation intersecting with Thymine. His Virus study incorporates themes from Cell culture and Molecular biology. His work in the fields of Biochemistry, such as Adenosine, Ribose and Binding site, overlaps with other areas such as Toxoplasma gondii.
Chung K. Chu spends much of his time researching Stereochemistry, Nucleoside, Chemical synthesis, Biological activity and Virus. His studies in Stereochemistry integrate themes in fields like Enzyme, Active site and In vitro, Structure–activity relationship. His study in Nucleoside is interdisciplinary in nature, drawing from both Mechanism of action and Nucleotidyltransferase.
The Biological activity study combines topics in areas such as Combinatorial chemistry, Resistance mutation, Molecule and Thymidine. The research on Virology and Immunology is part of his Virus project. His work deals with themes such as Thymine and Drug resistance, which intersect with Virology.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides.
R F Schinazi;R M Lloyd;M H Nguyen;D L Cannon.
Antimicrobial Agents and Chemotherapy (1993)
Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes.
R F Schinazi;C K Chu;A Peck;A McMillan.
Antimicrobial Agents and Chemotherapy (1992)
Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication.
C.N. Chang;S.L. Doong;J.H. Zhou;J.W. Beach.
Journal of Biological Chemistry (1992)
Chemistry and antiviral activities of acyclonucleosides
Chung K. Chu;Stephen J. Cutler.
Journal of Heterocyclic Chemistry (1986)
Use of 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil as a novel antiviral agent for hepatitis B virus and Epstein-Barr virus.
C K Chu;T Ma;K Shanmuganathan;C Wang.
Antimicrobial Agents and Chemotherapy (1995)
Synthesis of enantiomerically pure (2'R,5'S)-(-)-1-(2-hydroxymethyloxathiolan-5-yl)cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV)
J. Warren Beach;Lak S. Jeong;Antonio J. Alves;Douglas Pohl.
Journal of Organic Chemistry (1992)
Epigenetic Silencing of HIV-1 by the Histone H3 Lysine 27 Methyltransferase Enhancer of Zeste 2
Julia Friedman;Won Kyung Cho;Chung K. Chu;Kara S. Keedy.
Journal of Virology (2011)
Nucleosides and nucleotides as antitumor and antiviral agents
Chung K. Chu;David C. Baker;Antiviral Agents.
Ribonucleoside Analogue That Blocks Replication of Bovine Viral Diarrhea and Hepatitis C Viruses in Culture
Lieven J. Stuyver;Tony Whitaker;Tamara R. McBrayer;Brenda I. Hernandez-Santiago.
Antimicrobial Agents and Chemotherapy (2003)
Asymmetric synthesis and biological evaluation of beta-L-(2R,5S)- and alpha-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential anti-HIV agents.
L. S. Jeong;R. F. Schinazi;J. W. Beach;H. O. Kim.
Journal of Medicinal Chemistry (1993)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: