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Karen S. Anderson

Karen S. Anderson

D-Index & Metrics

Biology and Biochemistry

D-Index
86
Citations
28209
World Ranking
2947
National Ranking
1509

Overview

Karen S. Anderson is affiliated with Yale University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with 47 publications, and Medicine, with 44 publications. Within these broader fields, their work focuses particularly on the subfields of Molecular Biology, Infectious Diseases, Epidemiology, Computational Theory and Mathematics, and Virology.

The main topics addressed in Anderson's research include HIV/AIDS drug development and treatment, SARS-CoV-2 and COVID-19 research, computational drug discovery methods, HIV research and treatment, RNA modifications and cancer, Pneumocystis jirovecii pneumonia detection and treatment, and epigenetics and DNA methylation.

Their frequent co-authors consist of:

  • William L. Jorgensen
  • Krasimir A. Spasov
  • Joseph A. Ippolito
  • Chunhui Zhang
  • Shalley N. Kudalkar

Anderson has published extensively in several key scientific venues, including:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • ACS Medicinal Chemistry Letters
  • Bioorganic & Medicinal Chemistry Letters
  • Proceedings of the National Academy of Sciences
  • npj Precision Oncology

Selected recent publications include:

  • Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations, 2021, ACS Central Science
  • Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2, 2020, ACS Medicinal Chemistry Letters
  • Structure-guided design of a perampanel-derived pharmacophore targeting the SARS-CoV-2 main protease, 2021, Structure
  • Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency, 2021, ACS Medicinal Chemistry Letters
  • Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Molecular Definition of Breast Tumor Heterogeneity

    Michail Shipitsin;Lauren L. Campbell;Pedram Argani;Stanislawa Weremowicz

  • The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors

    Lauren L.C. Marotta;Vanessa Almendro;Vanessa Almendro;Andriy Marusyk;Michail Shipitsin

  • Mechanism and fidelity of HIV reverse transcriptase.

    W. M. Kati;Kenneth Johnson;L. F. Jerva;K. S. Anderson

  • CCL18 from Tumor-Associated Macrophages Promotes Breast Cancer Metastasis via PITPNM3

    Jingqi Chen;Jingqi Chen;Yandan Yao;Chang Gong;Fengyan Yu

  • Direct-drive inertial confinement fusion: A review

    R. S. Craxton;K. S. Anderson;T. R. Boehly;V. N. Goncharov

  • Presentation of viral antigen controlled by a gene in the major histocompatibility complex.

    V Cerundolo;J Alexander;K Anderson;C Lamb

  • Toxicity of Antiviral Nucleoside Analogs and the Human Mitochondrial DNA Polymerase

    Allison A. Johnson;Adrian S. Ray;Jeremiah W. Hanes;Zucai Suo

  • Classifying the evolutionary and ecological features of neoplasms

    Carlo C. Maley;Athena Aktipis;Trevor A. Graham;Andrea Sottoriva

  • The Sentinel Within: Exploiting the Immune System for Cancer Biomarkers†

    Karen S. Anderson;Joshua LaBaer

  • Dose-response Curve Slope Sets Class-Specific Limits on Inhibitory Potential of Anti-HIV Drugs

    Lin Shen;Susan Peterson;Ahmad R Sedaghat;Moira A McMahon

  • Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner

    Matthew J. Androlewicz;Karen S. Anderson;Peter Cresswell

  • Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes.

    Robert H. Vonderheide;Susan M. Domchek;Joachim L. Schultze;Daniel J. George

  • Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer's pathology.

    Taylor W. Schmitz;R. Nathan Spreng;Michael W. Weiner;Paul Aisen

  • Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction.

    Cristina M. Furdui;Erin D. Lew;Joseph Schlessinger;Karen S. Anderson

  • NeoPalAna: Neoadjuvant Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, and Anastrozole for Clinical Stage 2 or 3 Estrogen Receptor-Positive Breast Cancer.

    Cynthia X Ma;Feng Gao;Jingqin Luo;Donald W. Northfelt

  • Protein microarray signature of autoantibody biomarkers for the early detection of breast cancer.

    Karen S. Anderson;Sahar Sibani;Garrick Wallstrom;Ji Qiu

  • Oncologists' reluctance to accrue patients onto clinical trials: an Illinois Cancer Center study.

    Al B. Benson;Janet Prokop Pregler;Judy A. Bean;Alfred W. Rademaker

  • Endogenously synthesized peptide with an endoplasmic reticulum signal sequence sensitizes antigen processing mutant cells to class I-restricted cell-mediated lysis.

    K. Anderson;Peter Cresswell;M. Gammon;J. Hermes

  • Epidermal Growth Factor Receptor Mutants from Human Lung Cancers Exhibit Enhanced Catalytic Activity and Increased Sensitivity to Gefitinib

    Roseann Mulloy;Audrey Ferrand;Youngjoo Kim;Raffaella Sordella

  • Subregional neuroanatomical change as a biomarker for Alzheimer's disease

    Dominic Holland;James B. Brewer;Donald J. Hagler;Christine Fennema-Notestine

Frequent Co-Authors

Joshua LaBaer
Joshua LaBaer Arizona State University
William L. Jorgensen
William L. Jorgensen Yale University
Joachim L. Schultze
Joachim L. Schultze University of Bonn
Marshall R. Posner
Marshall R. Posner Icahn School of Medicine at Mount Sinai
Robert H. Vonderheide
Robert H. Vonderheide University of Pennsylvania
Daniel W. Cramer
Daniel W. Cramer Brigham and Women's Hospital
Richard Gray
Richard Gray University of Oxford
Lee M. Nadler
Lee M. Nadler Harvard University
Reisa A. Sperling
Reisa A. Sperling Brigham and Women's Hospital
Marilyn S. Albert
Marilyn S. Albert Johns Hopkins University School of Medicine

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