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Thierry Fontaine

Thierry Fontaine

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
9235
World Ranking
17182
National Ranking
733

Overview

Thierry Fontaine is affiliated with the Institut Pasteur in France and has contributed extensively to the fields of Medicine and Agricultural and Biological Sciences. Their research primarily intersects infectious diseases, plant science, epidemiology, molecular biology, and immunology, reflecting a multidisciplinary approach.

The scientist's work focuses notably on antifungal resistance and susceptibility, fungal infections and studies, polysaccharides and plant cell walls, as well as mechanisms related to neutrophils, myeloperoxidase, and oxidative processes. Additional research topics include glycosylation and glycoproteins, microbial natural products and biosynthesis, and mycotoxins in agriculture and food.

Thierry Fontaine has published in several scientific venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Fungi
  • The Cell Surface
  • Nature

Major recent papers by Thierry Fontaine include:

  • "A molecular vision of fungal cell wall organization by functional genomics and solid-state NMR," published in 2021 in Nature Communications
  • "Galactosaminogalactan activates the inflammasome to provide host protection," 2020, Nature
  • "Biotinylated Oligo-α-(1 → 4)-d-galactosamines and Their N-Acetylated Derivatives: α-Stereoselective Synthesis and Immunology Application," 2020, Journal of the American Chemical Society
  • "Galactomannan Produced by Aspergillus fumigatus: An Update on the Structure, Biosynthesis and Biological Functions of an Emblematic Fungal Biomarker," 2020, Journal of Fungi
  • "Functional Genomic and Biochemical Analysis Reveals Pleiotropic Effect of Congo Red on Aspergillus fumigatus," 2021, mBio

In collaboration, Thierry Fontaine has frequently worked with several researchers, including:

  • Jean-Paul Latgé
  • Vishukumar Aimanianda
  • Isabel Valsecchi
  • Sarah Sze Wah Wong
  • Neil A. R. Gow

The scientist's expertise spans diverse subfields and frequently published topics, reflecting a comprehensive understanding of fungal biology and host-pathogen interactions. Research outputs cover aspects ranging from molecular mechanisms in infectious diseases to the biosynthesis and immunological features of fungal polysaccharides.

Best Publications

  • Molecular organization of the alkali-insoluble fraction of Aspergillus fumigatus cell wall.

    Thierry Fontaine;Catherine Simenel;Guy Dubreucq;Olivier Adam

  • Glycosylphosphatidylinositol-anchored Glucanosyltransferases Play an Active Role in the Biosynthesis of the Fungal Cell Wall

    Isabelle Mouyna;Thierry Fontaine;Marina Vai;Michel Monod

  • Bacterial SLH domain proteins are non‐covalently anchored to the cell surface via a conserved mechanism involving wall polysaccharide pyruvylation

    Stéphane Mesnage;Thierry Fontaine;Tâm Mignot;Muriel Delepierre

  • Broad-spectrum biofilm inhibition by a secreted bacterial polysaccharide

    Jaione Valle;Sandra Da Re;Nelly Henry;Thierry Fontaine

  • Aspergillus galactosaminogalactan mediates adherence to host constituents and conceals hyphal β-glucan from the immune system.

    Fabrice N. Gravelat;Anne Beauvais;Hong Liu;Mark J. Lee

  • Waxy Chlamydomonas reinhardtii: monocellular algal mutants defective in amylose biosynthesis and granule-bound starch synthase activity accumulate a structurally modified amylopectin.

    B Delrue;T Fontaine;F Routier;A Decq

  • Galactosaminogalactan, a New Immunosuppressive Polysaccharide of Aspergillus fumigatus

    Thierry Fontaine;Aurélie Delangle;Catherine Simenel;Bernadette Coddeville

  • Immune Sensing of Aspergillus fumigatus Proteins, Glycolipids, and Polysaccharides and the Impact on Th Immunity and Vaccination

    Silvia Bozza;Cecile Clavaud;Gloria Giovannini;Thierry Fontaine

  • Deletion of GEL2 encoding for a beta(1-3)glucanosyltransferase affects morphogenesis and virulence in Aspergillus fumigatus.

    Isabelle Mouyna;Willy Morelle;Marina Vai;Michel Monod

  • Toward an understanding of the biogenesis of the starch granule. Evidence that Chlamydomonas soluble starch synthase II controls the synthesis of intermediate size glucans of amylopectin.

    T. Fontaine;C. D'Hulst;M.L. Maddelein;F. Routier

  • Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes

    Wade Abbott;Orly Alber;Ed Bayer;Jean-Guy Berrin

  • Cell Wall β-(1,6)-Glucan of Saccharomyces cerevisiae STRUCTURAL CHARACTERIZATION AND IN SITU SYNTHESIS

    Vishukumar Aimanianda;Cécile Clavaud;Catherine Simenel;Thierry Fontaine

  • The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps.

    Mark J. Lee;Hong Liu;Bridget M. Barker;Brendan D. Snarr

  • Molecular characterization of the Aspergillus nidulans treA gene encoding an acid trehalase required for growth on trehalose

    Christophe D'Enfert;Thierry Fontaine

  • A novel beta-(1-3)-glucanosyltransferase from the cell wall of Aspergillus fumigatus.

    Robbert P. Hartland;Thierry Fontaine;Jean-Paul Debeaupuis;Catherine Simenel

  • Systematic capsule gene disruption reveals the central role of galactose metabolism on Cryptococcus neoformans virulence.

    Frédérique Moyrand;Thierry Fontaine;Guilhem Janbon

  • Toward an understanding of the biogenesis of the starch granule. Determination of granule-bound and soluble starch synthase functions in amylopectin synthesis.

    M L Maddelein;N Libessart;F Bellanger;B Delrue

  • Aspergillus cell wall and biofilm.

    Anne Beauvais;Thierry Fontaine;Vishukumar Aimanianda;Jean-Paul Latgé

  • Modulation of intestinal inflammation by yeasts and cell wall extracts: strain dependence and unexpected anti-inflammatory role of glucan fractions.

    Samir Jawhara;Samir Jawhara;Khalid Habib;Khalid Habib;François Maggiotto;François Maggiotto;Georges Pignede

  • Glycosylphosphatidylinositol-anchored Fungal Polysaccharide in Aspergillus fumigatus

    Corina Costachel;Bernadette Coddeville;Jean-Paul Latgé;Thierry Fontaine

Frequent Co-Authors

Jean-Paul Latgé
Jean-Paul Latgé University of Crete
Muriel Delepierre
Muriel Delepierre Institut Pasteur
Bernard Henrissat
Bernard Henrissat Technical University of Denmark
Carole Elbim
Carole Elbim Sorbonne University
Luigina Romani
Luigina Romani University of Perugia
Scott G. Filler
Scott G. Filler University of California, Los Angeles
Silvia Bozza
Silvia Bozza University of Perugia
Emilia Mellado
Emilia Mellado Instituto de Salud Carlos III
Capucine Picard
Capucine Picard Université Paris Cité

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