D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 67 Citations 12,955 134 World Ranking 1768 National Ranking 905

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Mutation

His primary scientific interests are in Molecular biology, DNA polymerase, Mitochondrial DNA, Polymerase and DNA polymerase II. The various areas that William C. Copeland examines in his Molecular biology study include Mitochondrial DNA replication, Genome, Biochemistry, DNAJA3 and DNA repair. His research investigates the connection between DNA polymerase and topics such as DNA replication that intersect with problems in Deoxyribonucleoside triphosphate and Heart metabolism.

His work deals with themes such as Mutation, Point mutation and DNA, which intersect with Mitochondrial DNA. William C. Copeland has researched DNA polymerase II in several fields, including DNA polymerase delta and DNA clamp. As part of one scientific family, William C. Copeland deals mainly with the area of DNA clamp, narrowing it down to issues related to the DNA polymerase I, and often Primase.

His most cited work include:

  • Mitochondrial DNA in human malignancy. (399 citations)
  • Mitochondrial toxicity of NRTI antiviral drugs: an integrated cellular perspective. (393 citations)
  • Eukaryotic DNA polymerases: proposal for a revised nomenclature. (310 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Molecular biology, Mitochondrial DNA, DNA polymerase, Polymerase and Genetics. His Molecular biology study which covers Protein subunit that intersects with Specificity factor. His studies deal with areas such as Mutation, Mitochondrion and DNA as well as Mitochondrial DNA.

His DNA polymerase study incorporates themes from DNA polymerase delta, DNA polymerase II, DNA polymerase I and Primer. His DNA polymerase II study combines topics from a wide range of disciplines, such as DNA polymerase mu, DNA clamp and Primase. In his research, Nucleic acid is intimately related to Recombinant baculovirus, which falls under the overarching field of Polymerase.

He most often published in these fields:

  • Molecular biology (59.65%)
  • Mitochondrial DNA (43.86%)
  • DNA polymerase (43.27%)

What were the highlights of his more recent work (between 2012-2020)?

  • Mitochondrial DNA (43.86%)
  • Genetics (35.67%)
  • Mitochondrial disease (18.13%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Mitochondrial DNA, Genetics, Mitochondrial disease, Molecular biology and Mitochondrion. His Mitochondrial DNA research incorporates themes from Mutation, Polymerase and DNA polymerase. His DNA polymerase study combines topics in areas such as DNA polymerase delta, DNA clamp, DNA polymerase I and DNA polymerase II.

His work on Exonuclease and Exome sequencing as part of general Genetics research is frequently linked to Table, bridging the gap between disciplines. William C. Copeland interconnects Nucleotide excision repair, DNA repair and DNA replication in the investigation of issues within Molecular biology. His Mitochondrion research integrates issues from Protein subunit, Cerebellar ataxia and Mutagenesis.

Between 2012 and 2020, his most popular works were:

  • Mitochondria, energetics, epigenetics, and cellular responses to stress. (139 citations)
  • Human mitochondrial DNA replication machinery and disease. (103 citations)
  • Mitochondrial genome maintenance in health and disease (84 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Mutation

William C. Copeland mainly investigates Mitochondrial DNA, Genetics, Mitochondrial disease, Mitochondrion and Mitochondrial DNA replication. His biological study spans a wide range of topics, including Mutation, Molecular biology, Polymerase and DNA polymerase. His DNA polymerase research incorporates elements of Computational biology and DNA damage.

His work in the fields of Genetics, such as Human mitochondrial genetics, Human Phenotype Ontology and Annotation, intersects with other areas such as Data sharing. He combines subjects such as Reactive oxygen species and Epigenetics with his study of Mitochondrion. His work in Mitochondrial DNA replication addresses subjects such as Mitochondrial DNA depletion syndrome, which are connected to disciplines such as Point mutation and Homoplasmy.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mitochondrial toxicity of NRTI antiviral drugs: an integrated cellular perspective.

William Lewis;Brian J. Day;William C. Copeland.
Nature Reviews Drug Discovery (2003)

594 Citations

Mitochondrial DNA in human malignancy.

John S. Penta;F.M. Johnson;Joseph T. Wachsman;William C. Copeland.
Mutation Research-reviews in Mutation Research (2001)

590 Citations

Eukaryotic DNA polymerases: proposal for a revised nomenclature.

Peter M J Burgers;Eugene V. Koonin;Elspeth Bruford;Luis Blanco.
Journal of Biological Chemistry (2001)

399 Citations

Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase γ

Philip A. Ropp;William C. Copeland.
Genomics (1996)

328 Citations

Inherited mitochondrial diseases of DNA replication.

William C. Copeland.
Annual Review of Medicine (2008)

306 Citations

DNA polymerase gamma in mitochondrial DNA replication and repair.

Maria A. Graziewicz;Matthew J. Longley;William C. Copeland.
Chemical Reviews (2006)

295 Citations

Molecular and clinical genetics of mitochondrial diseases due to POLG mutations

Lee Jun C Wong;Robert K. Naviaux;Nicola Brunetti-Pierri;Qing Zhang.
Human Mutation (2008)

278 Citations

The Fidelity of Human DNA Polymerase γ with and without Exonucleolytic Proofreading and the p55 Accessory Subunit

Matthew J. Longley;Dinh Nguyen;Thomas A. Kunkel;William C. Copeland.
Journal of Biological Chemistry (2001)

264 Citations

Mitochondrial DNA alterations in cancer.

William C. Copeland;Joseph T. Wachsman;F. M. Johnson;John S. Penta.
Cancer Investigation (2002)

256 Citations

The Mitochondrial p55 Accessory Subunit of Human DNA Polymerase γ Enhances DNA Binding, Promotes Processive DNA Synthesis, and Confers N-Ethylmaleimide Resistance

Susan E. Lim;Matthew J. Longley;William C. Copeland.
Journal of Biological Chemistry (1999)

252 Citations

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