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Medicine

D-Index
76
Citations
16263
World Ranking
18937
National Ranking
9440

Overview

Brian J. Day is affiliated with National Jewish Health in the United States and has contributed extensively to medical research. Their work primarily spans the field of medicine, with a strong focus on immunology, health, toxicology and mutagenesis, epidemiology, biochemistry, and pharmacology.

Their research emphasizes several core topics including:

  • Air Quality and Health Impacts
  • Respiratory viral infections research
  • Asthma and respiratory diseases
  • Climate Change and Health Impacts
  • Sulfur Compounds in Biology
  • IL-33, ST2, and ILC Pathways
  • Influenza Virus Research Studies

Brian J. Day's work has been published in a variety of scientific journals. Frequent publication venues include:

  • Free Radical Biology and Medicine
  • Journal of Pharmacology and Experimental Therapeutics
  • Disaster Medicine and Public Health Preparedness
  • International Journal of Molecular Sciences
  • Journal of Inflammation Research

Representative recent papers authored or co-authored by Brian J. Day are:

  • Nicotine-Free e-Cigarette Vapor Exposure Stimulates IL6 and Mucin Production in Human Primary Small Airway Epithelial Cells (2020, Journal of Inflammation Research)
  • Myeloperoxidase inhibition decreases morbidity and oxidative stress in mice with cystic fibrosis-like lung inflammation (2020, Free Radical Biology and Medicine)
  • Electronic Cigarette Exposure Increases the Severity of Influenza a Virus Infection via TRAIL Dysregulation in Human Precision-Cut Lung Slices (2023, International Journal of Molecular Sciences)
  • Electronic cigarette vapor exposure exaggerates the pro-inflammatory response during influenza A viral infection in human distal airway epithelium (2022, Archives of Toxicology)
  • IL-33/ST2 signaling modulates Afghanistan particulate matter induced airway hyperresponsiveness in mice (2020, Toxicology and Applied Pharmacology)

The scientist frequently collaborates with other researchers. Notable co-authors include:

  • Hong Wei Chu
  • Niccolette Schaunaman
  • Mari Numata
  • Elysia Min
  • Gregory P. Downey

Best Publications

  • Mitochondrial toxicity of NRTI antiviral drugs: an integrated cellular perspective.

    William Lewis;Brian J. Day;William C. Copeland

  • A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

    Simon Melov;Julie A. Schneider;Brian J. Day;Douglas Hinerfeld

  • Reactive Oxygen Species Regulate Activation-Induced T Cell Apoptosis

    David A Hildeman;Tom Mitchell;T.Kent Teague;Peter Henson

  • Requirement for superoxide in excitotoxic cell death.

    Manisha Patel;Brian J. Day;James D. Crapo;Irwin Fridovich

  • Manganic porphyrins possess catalase activity and protect endothelial cells against hydrogen peroxide-mediated injury

    Brian J. Day;Irwin Fridovich;James D. Crapo

  • Basal and stimulated protein S-nitrosylation in multiple cell types and tissues.

    Andrew J. Gow;Qiping Chen;Douglas T. Hess;Brian J. Day

  • Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger

    Csaba Szabó;Brian J. Day;Andrew L. Salzman

  • Extracellular superoxide dismutase: a regulator of nitric oxide bioavailability.

    Oury Td;Day Bj;Crapo Jd

  • Catalase and glutathione peroxidase mimics

    Brian J. Day

  • Extracellular superoxide dismutase in vessels and airways of humans and baboons

    Tim D. Oury;Brian J. Day;James D. Crapo

  • A mechanism of paraquat toxicity involving nitric oxide synthase

    Brian J. Day;Manisha Patel;Lisa Calavetta;Ling Yi Chang

  • A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced endothelial cell injury, in vitro.

    B J Day;S Shawen;S I Liochev;J D Crapo

  • Immunocytochemical localization of extracellular superoxide dismutase in human lung.

    T. D. Oury;Ling-Yi Chang;S. L. Marklund;B. J. Day

  • Multiple and Additive Functions of ALDH3A1 and ALDH1A1: CATARACT PHENOTYPE AND OCULAR OXIDATIVE DAMAGE IN Aldh3a1(−/−)/Aldh1a1(−/−) KNOCK-OUT MICE

    Natalie Lassen;J. Bronwyn Bateman;Tia Estey;Jer R. Kuszak

  • A Metalloporphyrin-Based Superoxide Dismutase Mimic Inhibits Adoptive Transfer of Autoimmune Diabetes by a Diabetogenic T-Cell Clone

    Jon D. Piganelli;Sonia C. Flores;Coral Cruz;Jeffrey Koepp

  • The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock

    Basilia Zingarelli;Brian J Day;James D Crapo;Andrew L Salzman

  • Targeting the Achilles Heel of Multidrug-Resistant Cancer by Exploiting the Fitness Cost of Resistance

    Gergely Szakács;Matthew D. Hall;Michael M. Gottesman;Ahcène Boumendjel

  • Attenuation of bleomycin-induced pulmonary fibrosis by a catalytic antioxidant metalloporphyrin.

    Tim D. Oury;Kailas Thakker;Margaret Menache;Ling-Yi Chang

  • Neuroprotection from Delayed Postischemic Administration of a Metalloporphyrin Catalytic Antioxidant

    G. Burkhard Mackensen;Manisha Patel;Huaxin Sheng;Carla L. Calvi

  • Mitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors.

    William Lewis;William C Copeland;Brian J Day

Frequent Co-Authors

Carl W. White
Carl W. White University of Colorado Denver
James D. Crapo
James D. Crapo National Jewish Health
Hong Wei Chu
Hong Wei Chu National Jewish Health
Lee S. Newman
Lee S. Newman University of Colorado Anschutz Medical Campus
Richard J. Martin
Richard J. Martin Case Western Reserve University
Ines Batinic-Haberle
Ines Batinic-Haberle Duke University
Tim D. Oury
Tim D. Oury University of Pittsburgh
William C. Copeland
William C. Copeland National Institutes of Health
Russell P. Bowler
Russell P. Bowler Cleveland Clinic
Irwin Fridovich
Irwin Fridovich Duke University

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