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Ines Batinic-Haberle

Ines Batinic-Haberle

D-Index & Metrics

Chemistry

D-Index
73
Citations
16059
World Ranking
5084
National Ranking
1584

Overview

Ines Batinic-Haberle is affiliated with Duke University in the United States and has a research portfolio spanning medicine and biochemistry, genetics, and molecular biology. Their work primarily focuses on molecular biology with notable engagement in related subfields including pulmonary and respiratory medicine, materials chemistry, biomedical engineering, and genetics.

The scientist's research addresses several main topics, including:

  • Porphyrin and phthalocyanine chemistry
  • Nanoplatforms for cancer theranostics
  • Heme oxygenase-1 and carbon monoxide
  • Vitamin C and antioxidants research
  • Photodynamic therapy research studies
  • Glioma diagnosis and treatment
  • Metal-catalyzed oxygenation mechanisms

Notable recent papers include:

  • H2O2-Driven Anticancer Activity of Mn Porphyrins and the Underlying Molecular Pathways, 2021, Oxidative Medicine and Cellular Longevity
  • Evaluation of the compounds commonly known as superoxide dismutase and catalase mimics in cellular models, 2021, Journal of Inorganic Biochemistry
  • Mn porphyrins as a novel treatment targeting sickle cell NOXs to reverse and prevent acute vaso-occlusion in vivo, 2020, Blood Advances
  • Antibacterial Activity of Synthetic Cationic Iron Porphyrins, 2020, Antioxidants
  • MnTnHex-2-PyP5+, Coupled to Radiation, Suppresses Metastasis of 4T1 and MDA-MB-231 Breast Cancer via AKT/Snail/EMT Pathways, 2021, Antioxidants

The frequent coauthors collaborating with Ines Batinic-Haberle include:

  • Ivan Spasojević
  • Artak Tovmasyan
  • Huaxin Sheng
  • Angeles Alvarez Secord
  • Weina Duan

Publications are often found in journals such as:

  • Free Radical Biology and Medicine
  • Antioxidants
  • Oxidative Medicine and Cellular Longevity
  • International Journal of Molecular Sciences
  • Gynecologic Oncology

Within their fields of study, Ines Batinic-Haberle has contributed to numerous research articles focused on intersecting domains of medicine and biochemistry, genetics, and molecular biology. Their work exhibits a multidisciplinary approach, integrating chemistry with biomedical applications particularly in cancer and oxidative stress-related processes.

Best Publications

  • Oxidants, antioxidants and the ischemic brain

    David S. Warner;Huaxin Sheng;Ines Batinić-Haberle

  • Superoxide Dismutase Mimics: Chemistry, Pharmacology, and Therapeutic Potential

    Ines Batinić-Haberle;Júlio S. Rebouças;Ivan Spasojević

  • Manganese superoxide dismutase, MnSOD and its mimics

    Sumitra Miriyala;Ivan Spasojevic;Artak Tovmasyan;Daniela Salvemini

  • Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease

    Mutay Aslan;Thomas M. Ryan;Brian Adler;Tim M. Townes

  • Relationship among Redox Potentials, Proton Dissociation Constants of Pyrrolic Nitrogens, and in Vivo and in Vitro Superoxide Dismutating Activities of Manganese(III) and Iron(III) Water-Soluble Porphyrins

    † Ines Batinić-Haberle;Ivan Spasojević;Peter Hambright;Ludmil Benov

  • The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic.

    Ines Batinic-Haberle;Ludmil Benov;Ivan Spasojevic;Irwin Fridovich

  • p53 Translocation to Mitochondria Precedes Its Nuclear Translocation and Targets Mitochondrial Oxidative Defense Protein-Manganese Superoxide Dismutase

    Yunfeng Zhao;Luksana Chaiswing;Joyce M. Velez;Ines Batinic-Haberle

  • SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways

    Ines Batinic-Haberle;Artak Tovmasyan;Emily R. H. Roberts;Zeljko Vujaskovic

  • A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury.

    Zeljko Vujaskovic;Ines Batinic-Haberle;Zahid N. Rabbani;Qin fu Feng

  • Antioxidative, Antinitrative, and Vasculoprotective Effects of a Peroxisome Proliferator–Activated Receptor-γ Agonist in Hypercholesterolemia

    Ling Tao;Hui-Rong Liu;Erhe Gao;Zhi-Ping Teng

  • A Metalloporphyrin-Based Superoxide Dismutase Mimic Inhibits Adoptive Transfer of Autoimmune Diabetes by a Diabetogenic T-Cell Clone

    Jon D. Piganelli;Sonia C. Flores;Coral Cruz;Jeffrey Koepp

  • Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.

    Gerardo Ferrer-Sueta;Darío Vitturi;Ines Batinić-Haberle;Irwin Fridovich

  • Neuroprotection from Delayed Postischemic Administration of a Metalloporphyrin Catalytic Antioxidant

    G. Burkhard Mackensen;Manisha Patel;Huaxin Sheng;Carla L. Calvi

  • Metalloporphyrins are potent inhibitors of lipid peroxidation.

    Brian J Day;Ines Batinic-Haberle;James D Crapo

  • New class of potent catalysts of O2˙− dismutation. Mn(III)ortho-methoxyethylpyridyl- and di-ortho-methoxyethylimidazolylporphyrins

    Ines Batinić-Haberle;Ivan Spasojević;Robert D. Stevens;Peter Hambright

  • Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants.

    Gerardo Ferrer-Sueta;Ines Batinić-Haberle;Ivan Spasojević;Irwin Fridovich

  • A potent superoxide dismutase mimic: manganese beta-octabromo-meso-tetrakis-(N-methylpyridinium-4-yl) porphyrin.

    Ines Batinić-Haberle;Stefan I. Liochev;Ivan Spasojević;Irwin Fridovich

  • Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.

    Ines Batinić-Haberle;Salvatore Cuzzocrea;Júlio S. Rebouças;Gerardo Ferrer-Sueta

  • NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

    Eui Jung Moon;Pierre Sonveaux;Paolo E. Porporato;Pierre Danhier

  • Manganese(III) meso-tetrakis(ortho-N-alkylpyridyl)porphyrins. Synthesis, characterization, and catalysis of O2˙− dismutation

    Ines Batinić-Haberle;Ivan Spasojević;Robert. D. Stevens;Peter Hambright

  • A neuronal model of Alzheimer's disease: An insight into the mechanisms of oxidative stress–mediated mitochondrial injury

    P. Sompol;W. Ittarat;J. Tangpong;Y. Chen

Frequent Co-Authors

Ivan Spasojevic
Ivan Spasojevic Duke University
Mark W. Dewhirst
Mark W. Dewhirst Duke University
Irwin Fridovich
Irwin Fridovich Duke University
David S. Warner
David S. Warner Duke University
Daret K. St. Clair
Daret K. St. Clair University of Kentucky
James D. Crapo
James D. Crapo National Jewish Health
Brian J. Day
Brian J. Day National Jewish Health
Rafael Radi
Rafael Radi University of the Republic
Ting-Ting Huang
Ting-Ting Huang Stanford University
Alvin L. Crumbliss
Alvin L. Crumbliss Duke University

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