What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Mitochondrial DNA, Mitochondrion, Molecular biology, Genetics and DNA replication.
Howard T. Jacobs combines subjects such as Mutation, Point mutation and DNA with his study of Mitochondrial DNA.
His Mitochondrion research includes elements of Oxidative phosphorylation and Genome.
His Molecular biology research incorporates elements of TFAM and DNA polymerase II.
Howard T. Jacobs interconnects Hypoxia-inducible factors, Ciona intestinalis, Cytochrome c oxidase and Mitochondrial ROS in the investigation of issues within Alternative oxidase.
His work carried out in the field of Respiratory chain brings together such families of science as Oxidative stress, Reactive oxygen species and ATP synthase.
His most cited work include:
- Premature ageing in mice expressing defective mitochondrial DNA polymerase (1994 citations)
- Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria. (715 citations)
- Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages (678 citations)
What are the main themes of his work throughout his whole career to date?
Howard T. Jacobs mainly investigates Genetics, Mitochondrial DNA, Mitochondrion, Molecular biology and Cell biology.
His Gene, Mutant, Mutation, Mitochondrial disease and Phenotype investigations are all subjects of Genetics research.
Howard T. Jacobs has included themes like Point mutation, Genome and DNA, DNA replication in his Mitochondrial DNA study.
His Mitochondrion research is multidisciplinary, incorporating elements of Oxidative phosphorylation and Transfer RNA.
Howard T. Jacobs has researched Molecular biology in several fields, including Heteroplasmy, RNA, Promoter, DNA polymerase II and Transcription.
His work deals with themes such as Drosophila melanogaster and Gene knockdown, which intersect with Cell biology.
He most often published in these fields:
- Genetics (59.49%)
- Mitochondrial DNA (54.74%)
- Mitochondrion (59.85%)
What were the highlights of his more recent work (between 2016-2021)?
- Cell biology (39.42%)
- Alternative oxidase (41.24%)
- Mitochondrion (59.85%)
In recent papers he was focusing on the following fields of study:
Howard T. Jacobs mainly focuses on Cell biology, Alternative oxidase, Mitochondrion, Respiratory chain and Mitochondrial DNA.
His biological study spans a wide range of topics, including RNA, Mutant, Gene knockdown and Mitochondrial disease.
His Alternative oxidase research is classified as research in Biochemistry.
His Mitochondrion research includes themes of Golgi apparatus, Oxidative phosphorylation, Endocytosis and Metabolism.
The various areas that Howard T. Jacobs examines in his Respiratory chain study include Respiratory enzyme, Transgene, Drosophila melanogaster, Ciona intestinalis and ATP synthase.
His research in Mitochondrial DNA intersects with topics in DNA and Genotype.
Between 2016 and 2021, his most popular works were:
- Mitochondria are physiologically maintained at close to 50 °C. (124 citations)
- Perturbed Redox Signaling Exacerbates a Mitochondrial Myopathy (32 citations)
- Perturbed Redox Signaling Exacerbates a Mitochondrial Myopathy (32 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Cell biology, Mitochondrion, Alternative oxidase, Respiratory chain and Mitochondrial DNA.
His research integrates issues of Polyadenylation and Transfer RNA in his study of Cell biology.
The concepts of his Mitochondrion study are interwoven with issues in RNA, Translation, Messenger RNA and Protein biosynthesis.
His Alternative oxidase study combines topics in areas such as Autophagy, Mitochondrial myopathy, Mitochondrial disease and Myopathy.
His study in Respiratory chain is interdisciplinary in nature, drawing from both Reactive oxygen species, Cardiomyopathy and Transgene.
Mitochondrial DNA is a subfield of Gene that he investigates.
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