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D-Index & Metrics

Molecular Biology

D-Index
71
Citations
17758
World Ranking
1378
National Ranking
104

Ian J. Holt publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Ian J. Holt sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 158 publications — 41st percentile

41% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

Ian J. Holt D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Ian J. Holt sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 71 D-Index — 57th percentile

57% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Overview

Ian J. Holt is affiliated with the Medical Research Council in the United Kingdom. Their research primarily focuses on Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine. Within these fields, they have specialized in several subfields including Molecular Biology, Neurology, Clinical Biochemistry, Genetics, and Cardiology and Cardiovascular Medicine.

The scientist's work has covered a variety of topics including:

  • Mitochondrial Function and Pathology
  • RNA Research and Splicing
  • Metabolism and Genetic Disorders
  • ATP Synthase and ATPases Research
  • Nuclear Structure and Function
  • Amyotrophic Lateral Sclerosis Research
  • RNA modifications and cancer

Recent papers reflect the range of their research interests. Significant publications include:

  • "Recurrent De Novo NAHR Reciprocal Duplications in the ATAD3 Gene Cluster Cause a Neurogenetic Trait with Perturbed Cholesterol and Mitochondrial Metabolism," published in 2020 in The American Journal of Human Genetics
  • "2-Deoxy-D-glucose couples mitochondrial DNA replication with mitochondrial fitness and promotes the selection of wild-type over mutant mitochondrial DNA," published in 2021 in Nature Communications
  • "Defects of Nutrient Signaling and Autophagy in Neurodegeneration," published in 2022 in Frontiers in Cell and Developmental Biology
  • "Muscle cell differentiation and development pathway defects in Emery-Dreifuss muscular dystrophy," published in 2020 in Neuromuscular Disorders
  • "2 deoxy-D-glucose augments the mitochondrial respiratory chain in heart," published in 2022 in Scientific Reports

Their frequent co-authors include:

  • Antonella Spinazzola
  • Uxoa Fernández-Pelayo
  • Heidi R. Fuller
  • Mikel Muñoz-Oreja
  • Adolfo López de Munaín

The most common venues for publications by this scientist are:

  • Neuromuscular Disorders
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The American Journal of Human Genetics
  • Nature Communications
  • Frontiers in Cell and Developmental Biology

Best Publications

  • Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

    I. J. Holt;A. E. Harding;J. A. Morgan-Hughes

  • A new mitochondrial disease associated with mitochondrial DNA heteroplasmy

    I. J. Holt;A. E. Harding;R. K. H. Petty;J. A. Morgan-Hughes

  • Coupled Leading- and Lagging-Strand Synthesis of Mammalian Mitochondrial DNA

    Ian J Holt;Heather E Lorimer;Howard T Jacobs;Howard T Jacobs

  • Enzymatic removal of ribonucleotides from DNA is essential for Mammalian genome integrity and development

    Martin A.M. Reijns;Björn Rabe;Rachel E. Rigby;Pleasantine Mill

  • Minimizing the damage: repair pathways keep mitochondrial DNA intact

    Lawrence Kazak;Aurelio Reyes;Ian J. Holt

  • Blue Native electrophoresis to study mitochondrial and other protein complexes.

    Leo G J Nijtmans;Nadine S Henderson;Ian J Holt

  • PrimPol, an Archaic Primase/Polymerase Operating in Human Cells

    Sara García-Gómez;Aurelio Reyes;María I. Martínez-Jiménez;E. Sandra Chocrón

  • Mitochondrial myopathies: Clinical and biochemical features of 30 patients with major deletions of muscle mitochondrial DNA

    I. J. Holt;A. E. Harding;J. M. Cooper;J. M. Cooper;A. H. V. Schapira

  • Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication.

    Ming Yao Yang;Mark Bowmaker;Aurelio Reyes;Lodovica Vergani

  • Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand.

    Takehiro Yasukawa;Aurelio Reyes;Tricia J. Cluett;Ming Yao Yang

  • Pearson syndrome and mitochondrial encephalomyopathy in a patient with a deletion of mtDNA.

    M A McShane;S R Hammans;M Sweeney;I J Holt

  • Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number

    Henna Tyynismaa;Hiroshi Sembongi;Monika Bokori-Brown;Caroline Granycome

  • Mammalian Mitochondrial DNA Replicates Bidirectionally from an Initiation Zone

    Mark Bowmaker;Ming Yao Yang;Takehiro Yasukawa;Aurelio Reyes

  • The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization

    Jiuya He;Chih-Chieh Mao;Aurelio Reyes;Hiroshi Sembongi

  • Mitochondrial RNA Polymerase Is Needed for Activation of the Origin of Light-Strand DNA Replication

    Javier Miralles Fusté;Sjoerd Wanrooij;Elisabeth Jemt;Caroline E. Granycome

  • Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes

    D R Dunbar;P A Moonie;H T Jacobs;I J Holt

  • Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis

    J. He;H. M. Cooper;A. Reyes;M. Di Re

  • A Bidirectional Origin of Replication Maps to the Major Noncoding Region of Human Mitochondrial DNA

    Takehiro Yasukawa;Ming Yao Yang;Howard T. Jacobs;Howard T. Jacobs;Ian J. Holt

  • Human Mitochondrial DNA Replication

    Ian J. Holt;Aurelio Reyes

  • TEFM (c17orf42) is necessary for transcription of human mtDNA

    Michal Minczuk;Jiuya He;Anna M. Duch;Thijs J. Ettema

Frequent Co-Authors

Howard T. Jacobs
Howard T. Jacobs Tampere University
Johannes N. Spelbrink
Johannes N. Spelbrink Radboud University
Joanna Poulton
Joanna Poulton University of Oxford
Mingyao Yang
Mingyao Yang Sichuan Agricultural University
Kimitsuna Watanabe
Kimitsuna Watanabe National Institute of Advanced Industrial Science and Technology
Robert J. Crouch
Robert J. Crouch National Institutes of Health
Michal Minczuk
Michal Minczuk University of Cambridge
John E. Walker
John E. Walker University of Cambridge
Ian M. Fearnley
Ian M. Fearnley University of Cambridge
Tsutomu Suzuki
Tsutomu Suzuki University of Tokyo

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