What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Mitochondrial DNA, Genetics, Mitochondrion, Respiratory chain and Mutation.
His studies deal with areas such as Molecular biology and Regulation of gene expression as well as Mitochondrial DNA.
His Mitochondrion research is classified as research in Cell biology.
His Respiratory chain research includes themes of Electron transport chain, Electron Transport Chain Complex Proteins, Computational biology and Neurodegeneration.
His study in Mutation is interdisciplinary in nature, drawing from both Oxidative stress, Free-radical theory of aging, Ageing and Somatic cell.
Nils-Göran Larsson interconnects Knockout mouse, Mitochondrial myopathy and Skeletal muscle in the investigation of issues within TFAM.
His most cited work include:
- Premature ageing in mice expressing defective mitochondrial DNA polymerase (1994 citations)
- Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice (1199 citations)
- Mitochondrial transcription factor A regulates mtDNA copy number in mammals (612 citations)
What are the main themes of his work throughout his whole career to date?
Nils-Göran Larsson mostly deals with Mitochondrial DNA, Mitochondrion, Genetics, Cell biology and Molecular biology.
His Mitochondrial DNA research is multidisciplinary, incorporating elements of Mutation and Point mutation.
His work deals with themes such as Oxidative stress and Somatic cell, which intersect with Mutation.
His Mitochondrion research includes elements of Oxidative phosphorylation and Transcription.
His research in Cell biology intersects with topics in mitochondrial fusion, Knockout mouse, RNA and Gene knockout.
His TFAM research incorporates elements of Endocrinology, Internal medicine and DNA-binding protein.
He most often published in these fields:
- Mitochondrial DNA (75.50%)
- Mitochondrion (59.04%)
- Genetics (52.21%)
What were the highlights of his more recent work (between 2017-2021)?
- Mitochondrial DNA (75.50%)
- Cell biology (42.97%)
- Mitochondrion (59.04%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Mitochondrial DNA, Cell biology, Mitochondrion, Mitochondrial disease and Oxidative phosphorylation.
The Mitochondrial DNA portion of his research involves studies in Genetics and Gene.
His work on Mitochondrial nucleoid as part of general Cell biology research is often related to Snapshot, thus linking different fields of science.
The various areas that he examines in his Mitochondrion study include Nucleotide, Mitochondrial ribosome, Transcription and Mitochondrial translation.
In his research, Sequence alignment, Computational biology and DNA sequencing is intimately related to Genome, which falls under the overarching field of Mitochondrial disease.
His Oxidative phosphorylation study integrates concerns from other disciplines, such as Human disease, Respiratory chain and Pharmacology.
Between 2017 and 2021, his most popular works were:
- MitoTALEN reduces mutant mtDNA load and restores tRNA Ala levels in a mouse model of heteroplasmic mtDNA mutation (77 citations)
- Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA (52 citations)
- Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA (52 citations)
In his most recent research, the most cited papers focused on:
Nils-Göran Larsson mainly investigates Mitochondrial DNA, Mitochondrion, Mitochondrial disease, Genetics and Cell biology.
His Mitochondrial DNA study combines topics in areas such as Mutation, Point mutation and Heart metabolism.
He has researched Mutation in several fields, including Phenotype and Molecular biology.
His work in the fields of Mitochondrion, such as Inner mitochondrial membrane, intersects with other areas such as Lipid bilayer fusion.
His Mitochondrial disease research incorporates themes from Chronic progressive external ophthalmoplegia, Topoisomerase, TOP3A and DNA replication.
His Cell biology research is multidisciplinary, incorporating perspectives in Ribosome biogenesis, Biogenesis, Mitochondrial ribosome assembly and Pentatricopeptide repeat.
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