World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
94
Citations
33956
World Ranking
932
National Ranking
460

Research.com Recognitions

  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

David A. Clayton is affiliated with the Howard Hughes Medical Institute in the United States. Their research spans multiple disciplines including psychology, social sciences, and medicine, with a notable focus on the intersection of technology and aging populations.

The main fields of study for Clayton include:

  • Psychology
  • Social Sciences
  • Medicine

Subfields of Clayton's work delve into various aspects of human behavior and health:

  • Demography
  • Social Psychology
  • Health
  • Clinical Psychology
  • Neuropsychology and Physiological Psychology

Clayton's research topics cover:

  • Technology Use by Older Adults
  • Health disparities and outcomes
  • Aging and Gerontology Research
  • COVID-19 and Mental Health
  • Mental Health Treatment and Access
  • Innovative Human-Technology Interaction
  • Multiple Sclerosis Research Studies

They have contributed to several recent papers including:

  • "Like another human being in the room": a community case study of smart speakers to reduce loneliness in the oldest-old (2024), published in Frontiers in Psychology
  • A disease-specific convergence of host and Epstein-Barr virus genetics in multiple sclerosis (2025), published in Proceedings of the National Academy of Sciences
  • Social isolation and the role of AgeTech in a post-COVID world (2022), published in Healthcare Management Forum
  • "My Story": using a life story approach to build friendships between younger and older people to alleviate loneliness and social isolation (2022), published in Mental Health Review Journal

Clayton has collaborated frequently with the following co-authors:

  • Arlene Astell
  • Sandra D'Alfonso
  • Sergio E. Baranzini
  • Rosella Mechelli
  • Renato Umeton

Their publication venues include:

  • Frontiers in Psychology
  • Proceedings of the National Academy of Sciences
  • Healthcare Management Forum
  • Mental Health Review Journal

Clayton has also authored a book titled AgeTech for Staying Connected, published in 2025 under the series Synthesis Lectures on Technology and Health.

Among their recognitions, Clayton was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2005.

Best Publications

  • Sequence and gene organization of mouse mitochondrial DNA

    Maureen J. Bibb;Richard A. Van Etten;Catharine T. Wright;Mark W. Walberg

  • Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

    Nils-Göran Larsson;Jianming Wang;Hans Wilhelmsson;Anders Oldfors

  • Replication of animal mitochondrial DNA

    David A. Clayton

  • Mitochondrial DNA maintenance in vertebrates.

    Gerald S. Shadel;David A. Clayton

  • Replication and Transcription of Vertebrate Mitochondrial DNA

    David A. Clayton

  • Similarity of human mitochondrial transcription factor 1 to high mobility group proteins

    Melissa A. Parisi;David A. Clayton

  • The Number of Mitochondrial Deoxyribonucleic Acid Genomes in Mouse L and Human HeLa Cells: QUANTITATIVE ISOLATION OF MITOCHONDRIAL DEOXYRIBONUCLEIC ACID

    Daniel Bogenhagen;David A. Clayton

  • Molecular Genetic Aspects of Human Mitochondrial Disorders

    Nils-Göran Larsson;David A. Clayton

  • The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria

    David A. Clayton;Jackie N. Doda;Errol C. Friedberg

  • TRANSCRIPTION OF THE MAMMALIAN MITOCHONDRIAL GENOME

    David A. Clayton

  • Yeast mitochondrial RNA polymerase is homologous to those encoded by bacteriophages T3 and T7.

    Brian S. Masters;Lori L. Stohl;David A. Clayton

  • Purification and characterization of human mitochondrial transcription factor 1

    R P Fisher;D A Clayton

  • Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression

    Jianming Wang;H. Wilhelmsson;C. Graff;Hong Li

  • Sequence and properties of the human KB cell and mouse L cell D-loop regions of mitochondrial DNA

    Mark W. Walberg;David A. Clayton

  • Priming of human mitochondrial DNA replication occurs at the light-strand promoter.

    David D. Chang;David A. Clayton

  • Transcription and replication of animal mitochondrial DNAs.

    David A. Clayton

  • DNA wrapping and bending by a mitochondrial high mobility group-like transcriptional activator protein.

    R P Fisher;T Lisowsky;M A Parisi;D A Clayton

  • Mouse L cell mitochondrial DNA molecules are selected randomly for replication throughout the cell cycle

    Daniel Bogenhagen;David A. Clayton

  • Elongation of displacement-loop strands in human and mouse mitochondrial DNA is arrested near specific template sequences

    Jackie N. Doda;Catharine T. Wright;David A. Clayton

  • Initiation and beyond: multiple functions of the human mitochondrial transcription machinery.

    Nicholas D. Bonawitz;David A. Clayton;Gerald S. Shadel

Frequent Co-Authors

Gerald S. Shadel
Gerald S. Shadel Salk Institute for Biological Studies
Nils-Göran Larsson
Nils-Göran Larsson Karolinska Institute
Baoji Xu
Baoji Xu Scripps Research Institute
Anders Oldfors
Anders Oldfors University of Gothenburg
Gregory S. Barsh
Gregory S. Barsh Stanford University
John L.R. Rubenstein
John L.R. Rubenstein University of California, San Francisco
Errol C. Friedberg
Errol C. Friedberg The University of Texas Southwestern Medical Center
Uta Francke
Uta Francke Stanford University
Walter F. Bodmer
Walter F. Bodmer University of Oxford

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