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D-Index & Metrics

Molecular Biology

D-Index
84
Citations
27716
World Ranking
873
National Ranking
460

Gerald S. Shadel publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Gerald S. Shadel sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 158 publications — 41st percentile

41% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

Gerald S. Shadel D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Gerald S. Shadel sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 84 D-Index — 72nd percentile

72% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Overview

Gerald S. Shadel is affiliated with the Salk Institute for Biological Studies in the United States. Their research spans multiple fields with a strong focus on biochemistry, genetics, molecular biology, medicine, immunology, and microbiology.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Immunology and Microbiology

Subfields of particular focus are:

  • Molecular Biology
  • Immunology
  • Epidemiology
  • Cell Biology
  • Infectious Diseases

Shadel's research topics show a specialization in immune system functioning and mitochondrial biology. Key research themes include:

  • Interferon and immune responses
  • Mitochondrial Function and Pathology
  • Inflammasome and immune disorders
  • Ubiquitin and proteasome pathways
  • RNA modifications and cancer
  • Cytomegalovirus and herpesvirus research
  • Epigenetics and DNA Methylation

The scientist has published in several prominent venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Science
  • Immunity
  • Cell

Recent significant papers include:

  • "Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling" (2022, Immunity)
  • "SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2" (2021, Circulation Research)
  • "Apoptotic stress causes mtDNA release during senescence and drives the SASP" (2023, Nature)
  • "Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity" (2023, Cell)
  • "Mitochondrial DNA Release in Innate Immune Signaling" (2023, Annual Review of Biochemistry)

Frequent co-authors who have collaborated with Shadel include:

  • Uri Manor
  • Gladys R. Rojas
  • Cara R. Schiavon
  • Alva G. Sainz
  • Laura Newman

Best Publications

  • Mitochondrial DNA Stress Primes the Antiviral Innate Immune Response

    A. Phillip West;William Khoury-Hanold;Matthew Staron;Michal C. Tal

  • TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

    A. Phillip West;Igor E. Brodsky;Igor E. Brodsky;Christoph Rahner;Dong Kyun Woo

  • Mitochondria in innate immune responses

    A. Phillip West;Gerald S. Shadel;Sankar Ghosh

  • Mitochondrial DNA maintenance in vertebrates.

    Gerald S. Shadel;David A. Clayton

  • Mitochondrial ROS Signaling in Organismal Homeostasis

    Gerald S. Shadel;Tamas L. Horvath

  • Mitochondrial DNA in innate immune responses and inflammatory pathology

    A. Phillip West;Gerald S. Shadel

  • Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA

    Anthony Rongvaux;Ruaidhrí Jackson;Christian C D Harman;Tuo Li

  • Replicative and Chronological Aging in Saccharomyces cerevisiae

    Valter D. Longo;Gerald S. Shadel;Matt Kaeberlein;Matt Kaeberlein;Brian Kennedy;Brian Kennedy

  • Interventions to Slow Aging in Humans: Are We Ready?

    Valter D. Longo;Adam Antebi;Andrzej Bartke;Nir Barzilai

  • Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling

    Michal Caspi Tal;Miwa Sasai;Heung Kyu Lee;Brian Yordy

  • Reduced TOR Signaling Extends Chronological Life Span via Increased Respiration and Upregulation of Mitochondrial Gene Expression

    Nicholas D. Bonawitz;Marc Chatenay-Lapointe;Yong Pan;Gerald S. Shadel

  • SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2.

    Yuyang Lei;Jiao Zhang;Jiao Zhang;Cara R. Schiavon;Ming He

  • Initiation and beyond: multiple functions of the human mitochondrial transcription machinery.

    Nicholas D. Bonawitz;David A. Clayton;Gerald S. Shadel

  • Targeted Expression of Catalase to Mitochondria Prevents Age-Associated Reductions in Mitochondrial Function and Insulin Resistance

    Hui Young Lee;Cheol Soo Choi;Cheol Soo Choi;Andreas L. Birkenfeld;Tiago C. Alves

  • Regulation of Yeast Chronological Life Span by TORC1 via Adaptive Mitochondrial ROS Signaling

    Yong Pan;Elizabeth A. Schroeder;Alejandro Ocampo;Antoni Barrientos

  • Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence

    Michal Harel;Rona Ortenberg;Rona Ortenberg;Siva Karthik Varanasi;Kailash Chandra Mangalhara

  • Identification of the operator of the lux regulon from the Vibrio fischeri strain ATCC7744.

    Jerry H. Devine;Gerald S. Shadel;Thomas O. Baldwin

  • Revisiting the TCA cycle: signaling to tumor formation

    Nuno Raimundo;Bora E. Baysal;Gerald S. Shadel

  • A human mitochondrial transcription factor is related to RNA adenine methyltransferases and binds S-adenosylmethionine.

    Vicki McCulloch;Bonnie L. Seidel-Rogol;Gerald S. Shadel

  • Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis.

    Maria A. Lebedeva;Jana S. Eaton;Jana S. Eaton;Gerald S. Shadel

Frequent Co-Authors

David A. Clayton
David A. Clayton Howard Hughes Medical Institute
Susan M. Kaech
Susan M. Kaech Salk Institute for Biological Studies
Thomas O. Baldwin
Thomas O. Baldwin University of California, Riverside
Akiko Iwasaki
Akiko Iwasaki Yale University
Craig E. Cameron
Craig E. Cameron University of North Carolina at Chapel Hill
Paul W. Doetsch
Paul W. Doetsch National Institute of Environmental Health Sciences
Brian K. Kennedy
Brian K. Kennedy National University of Singapore
William C. Sessa
William C. Sessa Pfizer (United States)
Qin Yan
Qin Yan Yale University
David A. Sinclair
David A. Sinclair Harvard University

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