World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
9871
World Ranking
17965
National Ranking
7352

Overview

Qin Yan is affiliated with Yale University in the United States and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work extensively covers the subfields of Molecular Biology, Oncology, Immunology, Cancer Research, and Pulmonary and Respiratory Medicine.

Their research addresses a variety of main topics including:

  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Histone Deacetylase Inhibitors Research
  • Cancer-related gene regulation
  • Protein Degradation and Inhibitors
  • Interferon and immune responses
  • Cancer-related molecular mechanisms research

Qin Yan has contributed to several recent publications, including:

  • "Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection," 2020, Cell
  • "Cancer Epigenetics, Tumor Immunity, and Immunotherapy," 2020, Trends in Cancer
  • "KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements," 2021, Nature
  • "Potent BRD4 inhibitor suppresses cancer cell-macrophage interaction," 2020, Nature Communications
  • "Deep learning-enabled pelvic ultrasound images for accurate diagnosis of ovarian cancer in China: a retrospective, multicentre, diagnostic study," 2022, The Lancet Digital Health

Their frequent co-authors include Wesley L. Cai, Bin Liu, Jian Cao, Mingzhu Yin, and Jialong Fan, reflecting collaborations across a range of research projects.

Qin Yan has been published frequently in several scientific venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Communications
  • Biomaterials
  • Ore Geology Reviews

Best Publications

  • Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

    Emmanuelle Querido;Paola Blanchette;Qin Yan;Takumi Kamura

  • Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.

    Jin Wei;Mia Madel Alfajaro;Peter C. DeWeirdt;Ruth E. Hanna

  • The retinoblastoma binding protein RBP2 is an H3K4 demethylase.

    Robert J. Klose;Qin Yan;Qin Yan;Zuzana Tothova;Zuzana Tothova;Kenichi Yamane

  • Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA

    Min Wang;Chao Mao;Lianlian Ouyang;Yating Liu

  • Histone Ubiquitination and Deubiquitination in Transcription, DNA Damage Response, and Cancer

    Jian Cao;Qin Yan

  • The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

    Takumi Kamura;Michael N. Conrad;Qin Yan;Ronald C. Conaway

  • Immunological differences between primary and metastatic breast cancer.

    B. Szekely;V. Bossuyt;X. Li;V.B. Wali

  • EGLN1/c-Myc Induced Lymphoid-Specific Helicase Inhibits Ferroptosis through Lipid Metabolic Gene Expression Changes

    Yiqun Jiang;Chao Mao;Rui Yang;Bin Yan

  • An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting

    Jian Cao;Lizhen Wu;Shang-Min Zhang;Min Lu;Min Lu

  • Cancer Epigenetics, Tumor Immunity, and Immunotherapy

    Jian Cao;Qin Yan

  • The Hypoxia-Inducible Factor 2α N-Terminal and C-Terminal Transactivation Domains Cooperate To Promote Renal Tumorigenesis In Vivo

    Qin Yan;Steven Bartz;Mao Mao;Lianjie Li;Lianjie Li

  • pVHL Acts as an Adaptor to Promote the Inhibitory Phosphorylation of the NF-κB Agonist Card9 by CK2

    Haifeng Yang;Yoji Andrew Minamishima;Qin Yan;Susanne Schlisio

  • MUF1, A Novel Elongin BC-interacting Leucine-rich Repeat Protein That Can Assemble with Cul5 and Rbx1 to Reconstitute a Ubiquitin Ligase

    Takumi Kamura;Dennis Burian;Qin Yan;Qin Yan;Susan L. Schmidt

  • Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer

    Lauren P. Blair;Jian Cao;Mike Ran Zou;Joyce Sayegh

  • KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements.

    Shang-Min Zhang;Wesley L. Cai;Wesley L. Cai;Xiaoni Liu;Durga Thakral

  • The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C

    Xiaohua Niu;Ting Zhang;Lili Liao;Liang Zhou

  • Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer Metastasis

    Yu-Ching Teng;Cheng-Feng Lee;Ying-Shiuan Li;Yi-Ren Chen

  • Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

    Wenchu Lin;Jian Cao;Jiayun Liu;Michael L. Beshiri

  • Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.

    Paola Blanchette;Chi Ying Cheng;Qin Yan;Qin Yan;Gary Ketner

  • A role for mammalian Sin3 in permanent gene silencing

    Chris van Oevelen;Jinhua Wang;Patrik Asp;Qin Yan

Frequent Co-Authors

Joan Weliky Conaway
Joan Weliky Conaway The University of Texas Southwestern Medical Center
William G. Kaelin
William G. Kaelin Harvard University
Ya Cao
Ya Cao Central South University
Shuang Liu
Shuang Liu Purdue University West Lafayette
Ronald C. Conaway
Ronald C. Conaway The University of Texas Southwestern Medical Center
Xiaodong Cheng
Xiaodong Cheng The University of Texas MD Anderson Cancer Center
Lajos Pusztai
Lajos Pusztai Yale University
John R. Horton
John R. Horton The University of Texas MD Anderson Cancer Center
Marcus Bosenberg
Marcus Bosenberg Yale University
Akiko Iwasaki
Akiko Iwasaki Yale University

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