World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
20504
World Ranking
11708
National Ranking
5034

Overview

John R. Horton is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily spans the field of Medicine, with a notable focus on Infectious Diseases, Parasitology, Oncology, Ecology, and Small Animals.

The scientist's work addresses several main topics including parasitic diseases research and treatment, lymphatic system and diseases, parasites and host interactions, parasite biology and host interactions, helminth infection and control, mosquito-borne diseases and control, as well as diagnosis and treatment of venous diseases.

Frequent co-authors in their publications include Eric A. Ottesen, Charles Mackenzie, Achim Hoerauf, Ute Klarmann-Schulz, and Mariana Stephens.

The research has been presented in several publication venues, with the most frequent being the American Journal of Tropical Medicine and Hygiene, along with Antimicrobial Agents and Chemotherapy, Parasites & Vectors, PLoS Neglected Tropical Diseases, and International Health.

Recent papers featuring John R. Horton include:

  • The design and development of a multicentric protocol to investigate the impact of adjunctive doxycycline on the management of peripheral lymphoedema caused by lymphatic filariasis and podoconiosis (2020), Parasites & Vectors
  • A case for adoption of continuous albendazole treatment regimen for human echinococcal infections (2020), PLoS Neglected Tropical Diseases
  • Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Adults in an Open-Label Phase 1 Multiple Ascending Dose and Food Effect Study (2020), Antimicrobial Agents and Chemotherapy
  • Setting the stage for a Global Programme to Eliminate Lymphatic Filariasis: the first 125 years (1875-2000) (2020), International Health
  • Silybum marianum ethanolic extract: in vitro effects on protoscolices of Echinococcus granulosus G1 strain with emphasis on other Iranian medicinal plants (2021), Tropical Medicine and Health

Best Publications

  • Lymphatic mapping and sentinel node biopsy in the patient with breast cancer

    John J. Albertini;Gary H. Lyman;Charles Cox;Tim Yeatman

  • Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD) : a vehicle for direct determination of three-dimensional structure

    W A Hendrickson;J R Horton;D M LeMaster

  • Principles of Biomedical Ethics, fifth edition. T. L. Beauchamp & J. F. Childress. New York: Oxford University Press, 2001. xiv+454pp. Price £19.95. ISBN 0-19-514332-9

    John Horton

  • Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression

    Fei Lan;Robert E. Collins;Rossella De Cegli;Rossella De Cegli;Roman Alpatov

  • Clinical management of cystic echinococcosis: state of the art, problems, and perspectives.

    Thomas Junghanss;Antonio Menezes da Silva;John Horton;Peter L. Chiodini

  • The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix

    Hideharu Hashimoto;John R. Horton;Xing Zhang;Magnolia Bostick

  • A Four-Month Gatifloxacin-Containing Regimen for Treating Tuberculosis

    Corinne S. Merle;Katherine Fielding;Omou Bah Sow;Martin Gninafon

  • Structural basis for the product specificity of histone lysine methyltransferases.

    Xing Zhang;Zhe Yang;Seema I. Khan;John R. Horton

  • Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

    John R Horton;Anup K Upadhyay;Hank H Qi;Xing Zhang

  • Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294

    Yanqi Chang;Xing Zhang;John R. Horton;Anup K. Upadhyay

  • The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin.

    Francisca E. Reyes-Turcu;John R. Horton;James E. Mullally;Annie Heroux

  • Structure of the Neurospora SET Domain Protein DIM-5, a Histone H3 Lysine Methyltransferase

    Xing Zhang;Hisashi Tamaru;Seema I. Khan;John R. Horton

  • The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules

    Robert E Collins;Jeffrey P Northrop;John R Horton;David Y Lee

  • Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.

    Hideharu Hashimoto;Dongxue Wang;John R. Horton;John R. Horton;Xing Zhang;Xing Zhang

  • A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability

    Pierre Olivier Estéve;Yanqi Chang;Mala Samaranayake;Anup K. Upadhyay

  • A New Primaquine Analogue, Tafenoquine (WR 238605), for Prophylaxis against Plasmodium falciparum Malaria

    G. Dennis Shanks;Aggrey J. Oloo;Gladys M. Aleman;Colin Ohrt

  • Comparison between CT-based volumetric calculations and ICRU reference-point estimates of radiation doses delivered to bladder and rectum during intracavitary radiotherapy for cervical cancer

    Christopher E. Pelloski;Matthew Palmer;Gregory M. Chronowski;Anuja Jhingran

  • Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia.

    Melissa B. Pappalardi;Kathryn Keenan;Mark Cockerill;Wendy A. Kellner

  • A PHASE II DOSE-INCREASING STUDY OF SITAMAQUINE FOR THE TREATMENT OF VISCERAL LEISHMANIASIS IN KENYA

    Tara K Jha;Shyam Sundar;Chandreshwar P Thakur;J Mark Felton

  • MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.

    Yanqi Chang;Lidong Sun;Kenji Kokura;John R. Horton

Frequent Co-Authors

Xiaodong Cheng
Xiaodong Cheng The University of Texas MD Anderson Cancer Center
Xing Zhang
Xing Zhang The University of Texas MD Anderson Cancer Center
Robert Blumenthal
Robert Blumenthal University of Toledo
Mark T. Bedford
Mark T. Bedford The University of Texas MD Anderson Cancer Center
Richard J. Roberts
Richard J. Roberts New England Biolabs
Geoffrey G. Wilson
Geoffrey G. Wilson New England Biolabs
Armando E. Gonzalez
Armando E. Gonzalez National University of San Marcos
Robert H. Gilman
Robert H. Gilman Johns Hopkins University
Gerd A. Blobel
Gerd A. Blobel Children's Hospital of Philadelphia
Haian Fu
Haian Fu Emory University

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