Brenda A. Schulman

Research.com Recognitions

• 2019 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics
• 2014 - Member of the National Academy of Sciences
• 2012 - Fellow of the American Academy of Arts and Sciences
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)

Overview

Best Publications

• Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.

  Ning Zheng;Brenda A. Schulman;Brenda A. Schulman;Langzhou Song;Julie J. Miller

  1745
  Citations

• Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.

  Charles G Mullighan;Xiaoping Su;Jinghui Zhang;Ina Radtke

  1631
  Citations

• Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity.

  Donghyuk Shin;Donghyuk Shin;Rukmini Mukherjee;Diana Grewe;Denisa Bojkova

  1118
  Citations

• Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways

  Brenda A. Schulman;J. Wade Harper

  1105
  Citations

• Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation

  David M. Duda;Laura A. Borg;Daniel C. Scott;Harold W. Hunt

  867
  Citations

• Structure of a β-TrCP1-Skp1-β-Catenin Complex: Destruction Motif Binding and Lysine Specificity of the SCFβ-TrCP1 Ubiquitin Ligase

  Geng Wu;Guozhou Xu;Brenda A. Schulman;Philip D. Jeffrey

  742
  Citations

• Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.

  Brenda A. Schulman;Andrea C. Carrano;Philip D. Jeffrey;Zachary Bowen

  739
  Citations

• JAK mutations in high-risk childhood acute lymphoblastic leukemia.

  Charles G. Mullighan;Jinghui Zhang;Richard C. Harvey;J. Racquel Collins-Underwood

  729
  Citations

• Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis

  Alban Ordureau;Shireen A. Sarraf;David M. Duda;Jin-Mi Heo

  682
  Citations

• Protein neddylation: beyond cullin-RING ligases.

  Radoslav I. Enchev;Brenda A. Schulman;Matthias Peter

  613
  Citations

• A Calcium-Regulated MEF2 Sumoylation Switch Controls Postsynaptic Differentiation

  Aryaman Shalizi;Brice Gaudillière;Zengqiang Yuan;Judith Stegmüller

  560
  Citations

• The SOCS box: a tale of destruction and degradation

  Benjamin T Kile;Brenda A Schulman;Warren S Alexander;Nicos A Nicola

  556
  Citations

• Parkin Is a Component of an SCF-like Ubiquitin Ligase Complex and Protects Postmitotic Neurons from Kainate Excitotoxicity

  John F. Staropoli;Caroline McDermott;Cécile Martinat;Brenda Schulman

  513
  Citations

• Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A

  Brenda A. Schulman;Derek L. Lindstrom;Ed Harlow

  510
  Citations

• Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.

  Min Zhuang;Matthew F. Calabrese;Jiang Liu;M. Brett Waddell

  471
  Citations

• Role of the F-box protein Skp2 in lymphomagenesis.

  Esther Latres;Roberto Chiarle;Brenda A. Schulman;Nikola P. Pavletich

  403
  Citations

• Building and remodelling Cullin-RING E3 ubiquitin ligases.

  John R Lydeard;Brenda A Schulman;J Wade Harper

  393
  Citations

• The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-α/β-induced ubiquitin-like protein

  Chen Zhao;Sylvie L. Beaudenon;Melissa L. Kelley;M. Brett Waddell

  375
  Citations

• A residue-specific NMR view of the non-cooperative unfolding of a molten globule

  Brenda A. Schulman;Peter S. Kim;Christopher M. Dobson;Christina Redfield

  360
  Citations

• Structural Mechanisms Underlying Posttranslational Modification by Ubiquitin-Like Proteins

  Billy T. Dye;Brenda A. Schulman

  347
  Citations