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Biology and Biochemistry

D-Index
86
Citations
24264
World Ranking
3003
National Ranking
225

Overview

Holger Stark is affiliated with the Max Planck Society in Germany. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with a significant number of publications in these areas. Within these fields, their work often addresses molecular biology, materials chemistry, computational mechanics, immunology, and condensed matter physics.

The scientist's research topics include:

  • RNA and protein synthesis mechanisms
  • RNA research and splicing
  • RNA modifications and cancer
  • Micro and nano robotics
  • Advanced electron microscopy techniques and applications
  • Electron and X-ray spectroscopy techniques
  • Fluid dynamics and turbulent flows

Holger Stark has frequently published in a variety of scientific venues, with multiple papers appearing in:

  • arXiv (Cornell University)
  • Default Digital Object Group
  • Nature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell

Some of their recent papers include:

  • "Atomic-resolution protein structure determination by cryo-EM", 2020, Nature
  • "Molecular architecture of the human 17S U2 snRNP", 2020, Nature
  • "Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation", 2020, Science
  • "Fatty Acid Synthase: Structure, Function, and Regulation", 2022, Sub-cellular biochemistry/Subcellular biochemistry
  • "Structural insights into how Prp5 proofreads the pre-mRNA branch site", 2021, Nature

Frequent collaborators of Holger Stark include:

  • Henning Urlaub
  • Ashwin Chari
  • Reinier van Buel
  • Cindy L. Will
  • Olexandr Dybkov

Best Publications

  • Self-assembly of a nanoscale DNA box with a controllable lid.

    Ebbe S. Andersen;Mingdong Dong;Morten M. Nielsen;Kasper Jahn

  • Single-particle electron cryo-microscopy: towards atomic resolution.

    M. van Heel;B. Gowen;R. Matadeen;E. V. Orlova

  • Atomic-resolution protein structure determination by cryo-EM

    Ka Man Yip;Niels Fischer;Elham Paknia;Ashwin Chari

  • GraFix: sample preparation for single-particle electron cryomicroscopy

    Berthold Kastner;Niels Fischer;Monika Mariola Golas;Bjoern Sander

  • Systematic analysis of human protein complexes identifies chromosome segregation proteins.

    James R. A. Hutchins;Yusuke Toyoda;Björn Hegemann;Ina Poser

  • Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures.

    S. C. Semple;S. K. Klimuk;T. O. Harasym;N. Dos Santos

  • Structural insight into filament formation by mammalian septins

    Minhajuddin Sirajuddin;Marian Farkasovsky;Florian Hauer;Dorothee Kühlmann

  • Structural Basis for the Function of the Ribosomal L7/12 Stalk in Factor Binding and GTPase Activation

    Mihaela Diaconu;Ute Kothe;Frank Schlünzen;Niels Fischer

  • Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

    Niels Fischer;Andrey L. Konevega;Wolfgang Wintermeyer;Marina V. Rodnina

  • Visualization of elongation factor Tu on the Escherichia coli ribosome

    H. Stark;M. V. Rodnina;J. Rinke-Appel;R. Brimacombe

  • Cryo-EM in drug discovery: achievements, limitations and prospects

    Jean-Paul Renaud;Ashwin Chari;Claudio Ciferri;Wen-Ti Liu

  • Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM.

    Niels Fischer;Piotr Neumann;Andrey L. Konevega;Lars V. Bock

  • Protein Composition and Electron Microscopy Structure of Affinity-Purified Human Spliceosomal B Complexes Isolated under Physiological Conditions

    Jochen Deckert;Klaus Hartmuth;Daniel Boehringer;Nastaran Behzadnia

  • The Evolutionarily Conserved Core Design of the Catalytic Activation Step of the Yeast Spliceosome

    Patrizia Fabrizio;Julia Dannenberg;Prakash Dube;Berthold Kastner

  • Molecular Architecture of the Multiprotein Splicing Factor SF3b

    Monika M. Golas;Bjoern Sander;Cindy L. Will;Reinhard Lührmann

  • Large-Scale Movement of Elongation Factor G and Extensive Conformational Change of the Ribosome during Translocation

    Holger Stark;Marina V Rodnina;Hans-Joachim Wieden;Marin van Heel

  • Arrangement of RNA and proteins in the spliceosomal U1 small nuclear ribonucleoprotein particle

    Holger Stark;Prakash Dube;Reinhard Lührmann;Berthold Kastner

  • biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes

    Florian Weissmann;Georg Petzold;Ryan VanderLinden;Pim J. Huis in 't Veld

  • Spontaneous entrapment of polynucleotides upon electrostatic interaction with ethanol-destabilized cationic liposomes.

    Norbert Maurer;Kim F. Wong;Holger Stark;Lenore Louie

  • Cryo-EM structure of a human spliceosome activated for step 2 of splicing

    Karl Bertram;Dmitry E. Agafonov;Wen-Ti Liu;Olexandr Dybkov

Frequent Co-Authors

Walter Schunack
Walter Schunack Freie Universität Berlin
Reinhard Lührmann
Reinhard Lührmann Max Planck Society
Jean-Charles Schwartz
Jean-Charles Schwartz Bioprojet (France)
Henning Urlaub
Henning Urlaub University of Göttingen
Jan-Michael Peters
Jan-Michael Peters Research Institute of Molecular Pathology
Kai Tittmann
Kai Tittmann University of Göttingen
Brenda A. Schulman
Brenda A. Schulman Max Planck Society
Marina V. Rodnina
Marina V. Rodnina Max Planck Society
Cindy L. Will
Cindy L. Will Max Planck Society
Wolfgang Wintermeyer
Wolfgang Wintermeyer Max Planck Society

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