Christian M. T. Spahn

What is he best known for?

The fields of study he is best known for:

• Gene
• Enzyme
• DNA

His main research concerns Ribosome, Eukaryotic Ribosome, Biochemistry, Transfer RNA and Biophysics. Christian M.T. Spahn has included themes like Translation and Cell biology in his Ribosome study. His research in Eukaryotic Ribosome intersects with topics in Ribosomal RNA, Protein subunit, Molecular biology, A-site and Eukaryotic Small Ribosomal Subunit.

His Ribosomal RNA study combines topics in areas such as P-site and 50S. Christian M.T. Spahn works in the field of Transfer RNA, focusing on 30S in particular. His Biophysics course of study focuses on Large ribosomal subunit and Ribosomal protein.

His most cited work include:

• Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit. (444 citations)
• Structure of the 80S Ribosome from Saccharomyces cerevisiae—tRNA-Ribosome and Subunit-Subunit Interactions (433 citations)
• Solution Structure of the E. coli 70S Ribosome at 11.5 Å Resolution (364 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Ribosome, Biochemistry, Transfer RNA, Ribosomal RNA and Eukaryotic Ribosome. The various areas that he examines in his Ribosome study include Molecular biology, Protein biosynthesis, Translation and Cell biology. His research integrates issues of Crystallography and Biophysics in his study of Transfer RNA.

His work deals with themes such as Protein structure, Large ribosomal subunit, EF-G and Phosphodiesterase, which intersect with Biophysics. Protein subunit is closely connected to 50S in his research, which is encompassed under the umbrella topic of Ribosomal RNA. Within one scientific family, Christian M.T. Spahn focuses on topics pertaining to Internal ribosome entry site under Eukaryotic Ribosome, and may sometimes address concerns connected to Eukaryotic initiation factor and Initiation factor.

He most often published in these fields:

• Ribosome (69.23%)
• Biochemistry (46.15%)
• Transfer RNA (44.62%)

What were the highlights of his more recent work (between 2017-2021)?

• Cell biology (25.38%)
• Ribosome (69.23%)
• Biophysics (39.23%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cell biology, Ribosome, Biophysics, Phosphodiesterase and Computational biology. His studies deal with areas such as Termination factor, RNA polymerase, Transcription, Protein subunit and DNA as well as Cell biology. His Ribosome research is multidisciplinary, incorporating perspectives in Ribosomal RNA, Proteostasis, Gene expression and Protein biosynthesis.

His work on Eukaryotic Large Ribosomal Subunit as part of general Ribosomal RNA study is frequently linked to Last universal ancestor, bridging the gap between disciplines. His research investigates the connection between Biophysics and topics such as Transport protein that intersect with problems in Prenylation, Binding protein, Solubilization and Membrane. His research on Computational biology also deals with topics like

• Translational regulation which intersects with area such as Proteome, Operon, Metabolic pathway, Escherichia coli and Rational design,
• Proteomics, which have a strong connection to Protein degradation and Translation.

Between 2017 and 2021, his most popular works were:

• Insights into the assembly and activation of the microtubule nucleator γ-TuRC (40 citations)
• Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor (32 citations)
• Alanine Tails Signal Proteolysis in Bacterial Ribosome-Associated Quality Control. (24 citations)

In his most recent research, the most cited papers focused on:

• Gene
• Enzyme
• DNA

His scientific interests lie mostly in Cell biology, Ribosome, RNA, Ribosomal RNA and 50S. He has included themes like Phosphodiesterase and Cyclic nucleotide phosphodiesterases in his Cell biology study. Christian M.T. Spahn has researched Ribosome in several fields, including Computational biology and Protein biosynthesis.

His RNA research includes elements of Proteome, Translational regulation, Protein degradation, Rational design and Proteomics. His Ribosomal RNA study focuses on Eukaryotic Large Ribosomal Subunit in particular. The concepts of his 50S study are interwoven with issues in Translation, Large ribosomal subunit, Peptidyl transferase and Proteolysis.