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Cindy L. Will

Cindy L. Will

D-Index & Metrics

Molecular Biology

D-Index
58
Citations
18716
World Ranking
2058
National Ranking
140

Overview

Cindy L. Will is affiliated with the Max Planck Society in Germany. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a notable emphasis on molecular biology within these fields.

The main topics of Cindy L. Will's work include RNA research and splicing, RNA modifications and cancer, and RNA and protein synthesis mechanisms. Additional research interests cover viral infections and immunology, RNA interference and gene delivery, protein structure and dynamics, and cancer-related molecular mechanisms.

Frequent publication venues for their work are:

  • Nature
  • Science
  • Science Advances
  • Molecular Cell
  • Nature Communications

Recent published papers by Cindy L. Will include:

  • "Molecular architecture of the human 17S U2 snRNP" (2020, Nature)
  • "Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation" (2020, Science)
  • "Structural insights into how Prp5 proofreads the pre-mRNA branch site" (2021, Nature)
  • "Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome" (2020, Molecular Cell)
  • "Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins" (2023, Science Advances)

The list of frequent co-authors collaborating with Cindy L. Will includes:

  • Henning Urlaub
  • Reinhard Lührmann
  • Olexandr Dybkov
  • Holger Stark
  • Berthold Kastner

Best Publications

  • The Spliceosome: Design Principles of a Dynamic RNP Machine

    Markus C. Wahl;Cindy L. Will;Reinhard Lührmann

  • Spliceosome structure and function.

    Cindy L. Will;Reinhard Lührmann

  • Spliceosomal UsnRNP biogenesis, structure and function.

    Cindy L Will;Reinhard Lührmann

  • Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

    Jhumku D. Kohtz;Sharon F. Jamison;Cindy L. Will;Ping Zuo;Ping Zuo

  • Isolation of an active step I spliceosome and composition of its RNP core.

    Sergey Bessonov;Maria Anokhina;Cindy L. Will;Henning Urlaub

  • Small Nuclear Ribonucleoprotein Remodeling During Catalytic Activation of the Spliceosome

    Evgeny M. Makarov;Olga V. Makarova;Henning Urlaub;Marc Gentzel

  • Dynamic Protein-Protein Interaction Wiring of the Human Spliceosome

    Anna Hegele;Atanas Kamburov;Arndt Grossmann;Chrysovalantis Sourlis

  • Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method.

    Klaus Hartmuth;Henning Urlaub;Hans-Peter Vornlocher;Cindy L. Will

  • Protein Composition and Electron Microscopy Structure of Affinity-Purified Human Spliceosomal B Complexes Isolated under Physiological Conditions

    Jochen Deckert;Klaus Hartmuth;Daniel Boehringer;Nastaran Behzadnia

  • Protein functions in pre-mRNA splicing

    Cindy L Will;Reinhard Lührmann

  • Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein.

    Cindy L. Will;Henning Urlaub;Tilmann Achsel;Marc Gentzel

  • Molecular Architecture of the Multiprotein Splicing Factor SF3b

    Monika M. Golas;Bjoern Sander;Cindy L. Will;Reinhard Lührmann

  • Cryo-EM structure of a human spliceosome activated for step 2 of splicing

    Karl Bertram;Dmitry E. Agafonov;Wen-Ti Liu;Olexandr Dybkov

  • Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation

    Karl Bertram;Dmitry E. Agafonov;Olexandr Dybkov;David Haselbach

  • Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion.

    Cyrille Girard;Cindy L. Will;Jianhe Peng;Evgeny M. Makarov

  • Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes

    Nastaran Behzadnia;Monika M Golas;Klaus Hartmuth;Bjoern Sander

  • HSPC117 is the essential subunit of a human tRNA splicing ligase complex.

    Johannes Popow;Markus Englert;Stefan Weitzer;Alexander Schleiffer

  • Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment.

    Christian Merz;Henning Urlaub;Cindy L. Will;Reinhard Lührmann

  • Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing

    Ramesh S. Pillai;Matthias Grimmler;Gunter Meister;Cindy L. Will

  • Semiquantitative Proteomic Analysis of the Human Spliceosome via a Novel Two-Dimensional Gel Electrophoresis Method

    Dmitry E. Agafonov;Jochen Deckert;Elmar Wolf;Peter Odenwälder

Frequent Co-Authors

Reinhard Lührmann
Reinhard Lührmann Max Planck Society
Henning Urlaub
Henning Urlaub University of Göttingen
Holger Stark
Holger Stark Max Planck Society
Markus C. Wahl
Markus C. Wahl Freie Universität Berlin
Matthias Wilm
Matthias Wilm University College Dublin
James L. Manley
James L. Manley Columbia University
Michael Sattler
Michael Sattler Technical University of Munich
Mariano A. Garcia-Blanco
Mariano A. Garcia-Blanco The University of Texas Medical Branch at Galveston
Juan Valcárcel
Juan Valcárcel Institució Catalana de Recerca i Estudis Avançats
Daniel Schümperli
Daniel Schümperli University of Bern

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