World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
92
Citations
37572
World Ranking
11161
National Ranking
5741

Overview

Alastair M. Thompson is affiliated with Baylor College of Medicine in the United States and has contributed extensively to research in medicine, with a particular focus on oncology and cancer-related studies. Their academic work spans multiple fields including medicine, biochemistry, genetics, and molecular biology, reflecting a multidisciplinary approach to cancer research and treatment.

Their primary subfields of study include:

  • Oncology
  • Cancer Research
  • Radiology, Nuclear Medicine and Imaging
  • Molecular Biology
  • Pathology and Forensic Medicine

Key research topics covered by their publications include:

  • Breast Cancer Treatment Studies
  • Cancer Genomics and Diagnostics
  • Breast Lesions and Carcinomas
  • Global Cancer Incidence and Screening
  • Cancer Cells and Metastasis
  • Radiomics and Machine Learning in Medical Imaging
  • Advanced Breast Cancer Therapies

Thompson has published in a variety of scientific journals, with frequent appearances in:

  • Cancer Research
  • Journal of Clinical Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • British Journal of Cancer
  • European Journal of Surgical Oncology

Several recent papers illustrate the scope of their research. These include:

  • "70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age" (2021, The Lancet Oncology)
  • "Spatial charting of single-cell transcriptomes in tissues" (2022, Nature Biotechnology)
  • "A spatially resolved single-cell genomic atlas of the adult human breast" (2023, Nature)
  • "Effect of Metformin vs Placebo on Invasive Disease-Free Survival in Patients With Breast Cancer" (2022, JAMA)
  • "Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group" (2020, npj Breast Cancer)

Their collaborative network includes frequent co-authors such as:

  • Elinor J. Sawyer
  • Sarah E. Pinder
  • Deborah Collyar
  • Jelle Wesseling
  • Esther H. Lips

This profile indicates a focused career in oncology research with a substantial contribution to breast cancer studies, cancer genomics, and diagnostic methodologies. Their work also integrates advanced technologies like machine learning applied to medical imaging, highlighting a combination of clinical and computational research approaches.

Best Publications

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Telomere reduction in human colorectal carcinoma and with ageing

    Nicholas D. Hastie;Maureen Dempster;Malcolm G. Dunlop;Alastair M. Thompson

  • 70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer

    Fatima Cardoso;Laura J. van’t Veer;Jan Bogaerts;Leen Slaets

  • Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial

    Jayant S Vaidya;Jayant S Vaidya;Frederik Wenz;Max Bulsara;Jeffrey S Tobias

  • HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

    Helen Davies;Dominik D. Glodzik;Sandro S. Morganella;Lucy R. Yates

  • Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1.

    Jong-Ho Cha;Wen-Hao Yang;Weiya Xia;Yongkun Wei

  • Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator

    Sonia Lain;Jonathan J. Hollick;Johanna Campbell;Oliver D. Staples

  • Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial

    Charlotte E Coles;Clare L Griffin;Anna M Kirby;Jenny Titley

  • Accelerated Partial Breast Irradiation: Executive summary for the update of an ASTRO Evidence-Based Consensus Statement.

    Candace Correa;Eleanor E. Harris;Maria Cristina Leonardi;Benjamin D. Smith

  • Quantitative shear wave ultrasound elastography: initial experience in solid breast masses

    Andrew Evans;Patsy Whelehan;Kim Thomson;Denis McLean

  • Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

    Suzanne A. Eccles;Eric O. Aboagye;Simak Ali;Annie S. Anderson

  • Mathematical modelling of tumour invasion and metastasis

    A. R. A. Anderson;M. A. J. Chaplain;E. L. Newman;R. J. C. Steele

  • Neoadjuvant trastuzumab, pertuzumab, and chemotherapy versus trastuzumab emtansine plus pertuzumab in patients with HER2-positive breast cancer (KRISTINE): a randomised, open-label, multicentre, phase 3 trial

    Sara A. Hurvitz;Miguel Martin;W. Fraser Symmans;Kyung Hae Jung

  • Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

    Y S Ju;L B Alexandrov;M Gerstung;I Martincorena

  • Cohort study examining tamoxifen adherence and its relationship to mortality in women with breast cancer.

    C. McCowan;J. Shearer;P. T. Donnan;J. A. Dewar

  • Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study

    Ellen R Copson;Tom C Maishman;Will J Tapper;Ramsey I Cutress

  • Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial

    Sirwan Hadad;Takayuki Iwamoto;Lee Jordan;Colin Purdie

  • A Pin1/mutant p53 axis promotes aggressiveness in breast cancer.

    Javier E. Girardini;Javier E. Girardini;Marco Napoli;Marco Napoli;Silvano Piazza;Alessandra Rustighi;Alessandra Rustighi

  • Cohort study of adherence to adjuvant endocrine therapy, breast cancer recurrence and mortality

    B. Makubate;P. T. Donnan;J. A. Dewar;Alastair Thompson

  • Invasive Breast Cancer: Relationship between Shear-wave Elastographic Findings and Histologic Prognostic Factors

    Andrew Evans;Patsy Whelehan;Kim Thomson;Denis McLean

Frequent Co-Authors

Elizabeth A. Mittendorf
Elizabeth A. Mittendorf Brigham and Women's Hospital
Sarah E Pinder
Sarah E Pinder King's College London
Vicente Valero
Vicente Valero The University of Texas MD Anderson Cancer Center
Andrew Evans
Andrew Evans University of Dundee
Banu Arun
Banu Arun The University of Texas MD Anderson Cancer Center
Naoto T. Ueno
Naoto T. Ueno University of Hawaiʻi Cancer Center
Kenneth R. Hess
Kenneth R. Hess The University of Texas MD Anderson Cancer Center
Kelly K. Hunt
Kelly K. Hunt The University of Texas MD Anderson Cancer Center
Elinor J. Sawyer
Elinor J. Sawyer King's College London
Jean-Christophe Bourdon
Jean-Christophe Bourdon University of Dundee

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